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REVISTA DE CHIMIE
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https://doi.org/10.37358/Rev.Chim.1949

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Revista de Chimie (Rev. Chim.), Year 2019, Volume 70, Issue 7, 2660-2664

https://doi.org/10.37358/RC.19.7.7400

Adelina Raluca Marinescu, Voichita Lazureanu, Ruxandra Laza, Virgil Musta, Narcisa Nicolescu, Monica Licker

Clostridium difficile Infection in Western Romania: Correlations Between Ribotype and Clinical Form One year observational retrospective study

Abstract:

Clostridium difficile is a globally significant enteric pathogen with rapid emergence in the USA, Asia, Oceania and Europe. It is reported to be the leading cause of infectious diarrhea in healthcare facilities of developed nations, and the burden of disease caused by this pathogen is receiving increasing recognition. The objectives of the present study consisted in determining the incidence of the C. difficile infection during the last year, correlating the ribotype with the clinical form of disease, as well as the quantification of the importance of the ATLAS score in the evolution of enterocolitis with C. difficile. Also, the secondary objectives of the study were: observation of the pathogens circulation in cases transferred from other hospital units and correlation of the current treatment versus existing antimicrobial guidelines. We have performed an observational retrospective study of Clostridium difficile enterocolitis cases in the Hospital of Infectious Diseases and Pneumophtisiology Victor Babes Timisoara, during January 2018- December 2018. Between January and December 2018, 207 patients with C. difficile acute enterocolitis were hospitalized. The Atlas scores remain of great utility in determining the prevalence of the infection. Of the 207 hospitalized patients in 18 cases, ribotyping was positive. All the 18 ribotypes were with binary toxin (cdt) and genotype 027, a strain commonly found in the west of the country, but also in countries with neighboring borders. Compared to the previous years, there is an alarming increase in the number of cases with C. difficile infection, ribotype 027. These isolates had another characteristic that no doubt contributed to their ability to spread quickly in a healthcare environment, they produced very high levels of spores compared to other C. difficile strains.
Keywords:
Clostridium difficile; ribotype; clinical form

Issue: 2019, Volume 70, Issue 7
Pages: 2660-2664
Publication date: 2019/8/15
https://doi.org/10.37358/RC.19.7.7400
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Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
MARINESCU, A.R., LAZUREANU, V., LAZA, R., MUSTA, V., NICOLESCU, N., LICKER, M., Clostridium difficile Infection in Western Romania: Correlations Between Ribotype and Clinical Form One year observational retrospective study, Rev. Chim., 70(7), 2019, 2660-2664.

Vancouver
Marinescu AR, Lazureanu V, Laza R, Musta V, Nicolescu N, Licker M. Clostridium difficile Infection in Western Romania: Correlations Between Ribotype and Clinical Form One year observational retrospective study. Rev. Chim.[internet]. 2019 Jul;70(7):2660-2664. Available from: https://doi.org/10.37358/RC.19.7.7400


APA 6th edition
Marinescu, A.R., Lazureanu, V., Laza, R., Musta, V., Nicolescu, N. & Licker, M. (2019). Clostridium difficile Infection in Western Romania: Correlations Between Ribotype and Clinical Form One year observational retrospective study. Revista de Chimie, 70(7), 2660-2664. https://doi.org/10.37358/RC.19.7.7400


Harvard
Marinescu, A.R., Lazureanu, V., Laza, R., Musta, V., Nicolescu, N., Licker, M. (2019). 'Clostridium difficile Infection in Western Romania: Correlations Between Ribotype and Clinical Form One year observational retrospective study', Revista de Chimie, 70(7), pp. 2660-2664. https://doi.org/10.37358/RC.19.7.7400


IEEE
A.R. Marinescu, V. Lazureanu, R. Laza, V. Musta, N. Nicolescu, M. Licker, "Clostridium difficile Infection in Western Romania: Correlations Between Ribotype and Clinical Form One year observational retrospective study". Revista de Chimie, vol. 70, no. 7, pp. 2660-2664, 2019. [online]. https://doi.org/10.37358/RC.19.7.7400


Text
Adelina Raluca Marinescu, Voichita Lazureanu, Ruxandra Laza, Virgil Musta, Narcisa Nicolescu, Monica Licker,
Clostridium difficile Infection in Western Romania: Correlations Between Ribotype and Clinical Form One year observational retrospective study,
Revista de Chimie,
Volume 70, Issue 7,
2019,
Pages 2660-2664,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.7.7400.
(https://revistadechimie.ro/Articles.asp?ID=7400)
Keywords: Clostridium difficile; ribotype; clinical form


RIS
TY - JOUR
T1 - Clostridium difficile Infection in Western Romania: Correlations Between Ribotype and Clinical Form One year observational retrospective study
A1 - Marinescu, Adelina Raluca
A2 - Lazureanu, Voichita
A3 - Laza, Ruxandra
A4 - Musta, Virgil
A5 - Nicolescu, Narcisa
A6 - Licker, Monica
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 7
SP - 2660
EP - 2664
UR - https://doi.org/10.37358/RC.19.7.7400
KW - Clostridium difficile
KW - ribotype
KW - clinical form
ER -


BibTex
@article{RevCh2019P2660,
author = {Marinescu Adelina Raluca and Lazureanu Voichita and Laza Ruxandra and Musta Virgil and Nicolescu Narcisa and Licker Monica},
title = {Clostridium difficile Infection in Western Romania: Correlations Between Ribotype and Clinical Form One year observational retrospective study},
journal = {Revista de Chimie},
volume = {70},
number = {7},
pages = {2660-2664},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.7.7400},
url = {https://revistadechimie.ro/Articles.asp?ID=7400}
}
 
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