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https://doi.org/10.37358/Rev.Chim.1949

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Revista de Chimie (Rev. Chim.), Year 2017, Volume 68, Issue 4, 720-725

https://doi.org/10.37358/RC.17.4.5538

Ana Maria Pelin, Cristian Catalin Gavat, Gabriela Balan, Eugenia Popescu, Costinela Valerica Georgescu

Particularities of Statin Therapy in Diabetic Patients

Abstract:

The purpose of conducted study was to determine which of the different types of statins ensure a better control of biological markers in diabetic patients and which of the lipid molecules studied, could be a first choice of lipid-lowering therapy in people suffering from diabetes. The measurement of blood glucose levels depending on type of statin used, was another target of this research. Dyslipidaemia was a major risk factor for cardiovascular complications in people with diabetes. It was found that atorvastatin was the most effective statin in controlling dyslipidemia in diabetic, because has ensured optimum control of HDL, LDL - cholesterol, triglycerides and glycemic values, effect which was resulted from the particular chemical structure of atorvastatin. Atorvastatin was discovered to be the best predictor in diabetes mellitus type 2 treatment, with a sensitivity about 78% and specificity to 45%., the most highest values compared to Rosuvastatin and Simvastatin. Area Under the Curve (AUC = 0.610; AUC ]0.600).
Keywords:
diabetes mellitus; statins; dyslipidemia; biological markers; competitive inhibitors

Issue: 2017, Volume 68, Issue 4
Pages: 720-725
Publication date: 2017/5/15
https://doi.org/10.37358/RC.17.4.5538
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Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
PELIN, A.M., GAVAT, C.C., BALAN, G., POPESCU, E., GEORGESCU, C.V., Particularities of Statin Therapy in Diabetic Patients, Rev. Chim., 68(4), 2017, 720-725.

Vancouver
Pelin AM, Gavat CC, Balan G, Popescu E, Georgescu CV. Particularities of Statin Therapy in Diabetic Patients. Rev. Chim.[internet]. 2017 Apr;68(4):720-725. Available from: https://doi.org/10.37358/RC.17.4.5538


APA 6th edition
Pelin, A.M., Gavat, C.C., Balan, G., Popescu, E. & Georgescu, C.V. (2017). Particularities of Statin Therapy in Diabetic Patients. Revista de Chimie, 68(4), 720-725. https://doi.org/10.37358/RC.17.4.5538


Harvard
Pelin, A.M., Gavat, C.C., Balan, G., Popescu, E., Georgescu, C.V. (2017). 'Particularities of Statin Therapy in Diabetic Patients', Revista de Chimie, 68(4), pp. 720-725. https://doi.org/10.37358/RC.17.4.5538


IEEE
A.M. Pelin, C.C. Gavat, G. Balan, E. Popescu, C.V. Georgescu, "Particularities of Statin Therapy in Diabetic Patients". Revista de Chimie, vol. 68, no. 4, pp. 720-725, 2017. [online]. https://doi.org/10.37358/RC.17.4.5538


Text
Ana Maria Pelin, Cristian Catalin Gavat, Gabriela Balan, Eugenia Popescu, Costinela Valerica Georgescu,
Particularities of Statin Therapy in Diabetic Patients,
Revista de Chimie,
Volume 68, Issue 4,
2017,
Pages 720-725,
ISSN 2668-8212,
https://doi.org/10.37358/RC.17.4.5538.
(https://revistadechimie.ro/Articles.asp?ID=5538)
Keywords: diabetes mellitus; statins; dyslipidemia; biological markers; competitive inhibitors


RIS
TY - JOUR
T1 - Particularities of Statin Therapy in Diabetic Patients
A1 - Pelin, Ana Maria
A2 - Gavat, Cristian Catalin
A3 - Balan, Gabriela
A4 - Popescu, Eugenia
A5 - Georgescu, Costinela Valerica
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2017
VL - 68
IS - 4
SP - 720
EP - 725
UR - https://doi.org/10.37358/RC.17.4.5538
KW - diabetes mellitus
KW - statins
KW - dyslipidemia
KW - biological markers
KW - competitive inhibitors
ER -


BibTex
@article{RevCh2017P720,
author = {Pelin Ana Maria and Gavat Cristian Catalin and Balan Gabriela and Popescu Eugenia and Georgescu Costinela Valerica},
title = {Particularities of Statin Therapy in Diabetic Patients},
journal = {Revista de Chimie},
volume = {68},
number = {4},
pages = {720-725},
year = {2017},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.17.4.5538},
url = {https://revistadechimie.ro/Articles.asp?ID=5538}
}
 
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