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REVISTA DE CHIMIE
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https://doi.org/10.37358/Rev.Chim.1949

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Revista de Chimie (Rev. Chim.), Year 2017, Volume 68, Issue 7, 1485-1489

https://doi.org/10.37358/RC.17.7.5701

Razan Al Namat, Viviana Aursulesei, Maura Gabriela Felea, Irina Iuliana Costache, Antoniu Petris, Ovidiu Mitu, Nadia Al Namat, Mihai Constantin, Dina Al Namat, Cristina Ghiciuc, Catalina Elena Lupusoru, Grigore Tinica, Florin Mitu

Heart-Type Fatty Acid-Binding Protein (H-FABP) in Patients with Coronary Artery Bypass Graft Surgery Undergoing Cardiac Rehabilitation Program

Abstract:

Heart-type Fatty Acid-Binding Protein (H-FABP), compared with classical biomarkers, proved to have high sensitivity for myocardial damage size in patients undergoing cardiac surgery. High H-FABP levels are strongly associated in case of death, post-operatively acute kidney injury and atrial fibrillation. Cardiac rehabilitation is an instrument of medical management in cardiovascular diseases; beyond prevention, it can improve heart and muscle functioning in patients that were undergoing CABG, and cardiac and vascular adaptation. Over a 2-year period, 110 subjects were randomized and comprehensively evaluated. The mean age of the patients under study was 65.70 ± 9.91 years old. For the H-FABP, the mean value in the Phase I was 67.40 ± 9.81 ng/mL, while the mean value in Phase III was 4.80 ± 2.30 ng/mL. The difference registered between the plasma H-FABP value in the first 24 h after cardiac surgery and the value in 6 months after the onset of cardiac rehabilitation program was important and statistically significant, as p [ 0.05. Fibrinogen showed significant phase-to-phase reductions of plasmatic values. Lipid profile values showed a statistically significant decrease. The renal filtration function evaluated by plasma creatinine showed statistically significant improvement and, in terms of absolute values, creatinine level was reduced in a range between 0.2-0.4 mg/dL. Also, it was recorded a significantly lower level of blood urea. The reduction of plasma H-FABP values were registered between the first phase (the first 24 h) after cardiac surgery and the third phase of the cardiac rehabilitation program. H-FABP protein had a higher sensitivity and specificity when compared to other enzymes of myocardial cytolysis.
Keywords:
heart-type fatty acid binding protein; coronary-artery bypass graft; cardiac rehabilitation

Issue: 2017, Volume 68, Issue 7
Pages: 1485-1489
Publication date: 2017/8/15
https://doi.org/10.37358/RC.17.7.5701
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Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
NAMAT, R.A., AURSULESEI, V., FELEA, M.G., COSTACHE, I.I., PETRIS, A., MITU, O., NAMAT, N.A., CONSTANTIN, M., NAMAT, D.A., GHICIUC, C., LUPUSORU, C.E., TINICA, G., MITU, F., Heart-Type Fatty Acid-Binding Protein (H-FABP) in Patients with Coronary Artery Bypass Graft Surgery Undergoing Cardiac Rehabilitation Program, Rev. Chim., 68(7), 2017, 1485-1489.

Vancouver
Namat RA, Aursulesei V, Felea MG, Costache II, Petris A, Mitu O, Namat NA, Constantin M, Namat DA, Ghiciuc C, Lupusoru CE, Tinica G, Mitu F. Heart-Type Fatty Acid-Binding Protein (H-FABP) in Patients with Coronary Artery Bypass Graft Surgery Undergoing Cardiac Rehabilitation Program. Rev. Chim.[internet]. 2017 Jul;68(7):1485-1489. Available from: https://doi.org/10.37358/RC.17.7.5701


APA 6th edition
Namat, R.A., Aursulesei, V., Felea, M.G., Costache, I.I., Petris, A., Mitu, O.,... Mitu, F. (2017). Heart-Type Fatty Acid-Binding Protein (H-FABP) in Patients with Coronary Artery Bypass Graft Surgery Undergoing Cardiac Rehabilitation Program. Revista de Chimie, 68(7), 1485-1489. https://doi.org/10.37358/RC.17.7.5701


Harvard
Namat, R.A., Aursulesei, V., Felea, M.G., Costache, I.I., Petris, A., Mitu, O., Namat, N.A., Constantin, M., Namat, D.A., Ghiciuc, C., Lupusoru, C.E., Tinica, G., Mitu, F. (2017). 'Heart-Type Fatty Acid-Binding Protein (H-FABP) in Patients with Coronary Artery Bypass Graft Surgery Undergoing Cardiac Rehabilitation Program', Revista de Chimie, 68(7), pp. 1485-1489. https://doi.org/10.37358/RC.17.7.5701


IEEE
R.A. Namat, V. Aursulesei, M.G. Felea, I.I. Costache, A. Petris, O. Mitu, N.A. Namat, M. Constantin, D.A. Namat, C. Ghiciuc, C.E. Lupusoru, G. Tinica, F. Mitu, "Heart-Type Fatty Acid-Binding Protein (H-FABP) in Patients with Coronary Artery Bypass Graft Surgery Undergoing Cardiac Rehabilitation Program". Revista de Chimie, vol. 68, no. 7, pp. 1485-1489, 2017. [online]. https://doi.org/10.37358/RC.17.7.5701


Text
Razan Al Namat, Viviana Aursulesei, Maura Gabriela Felea, Irina Iuliana Costache, Antoniu Petris, Ovidiu Mitu, Nadia Al Namat, Mihai Constantin, Dina Al Namat, Cristina Ghiciuc, Catalina Elena Lupusoru, Grigore Tinica, Florin Mitu,
Heart-Type Fatty Acid-Binding Protein (H-FABP) in Patients with Coronary Artery Bypass Graft Surgery Undergoing Cardiac Rehabilitation Program,
Revista de Chimie,
Volume 68, Issue 7,
2017,
Pages 1485-1489,
ISSN 2668-8212,
https://doi.org/10.37358/RC.17.7.5701.
(https://revistadechimie.ro/Articles.asp?ID=5701)
Keywords: heart-type fatty acid binding protein; coronary-artery bypass graft; cardiac rehabilitation


RIS
TY - JOUR
T1 - Heart-Type Fatty Acid-Binding Protein (H-FABP) in Patients with Coronary Artery Bypass Graft Surgery Undergoing Cardiac Rehabilitation Program
A1 - Namat, Razan Al
A2 - Aursulesei, Viviana
A3 - Felea, Maura Gabriela
A4 - Costache, Irina Iuliana
A5 - Petris, Antoniu
A6 - Mitu, Ovidiu
A7 - Namat, Nadia Al
A8 - Constantin, Mihai
A9 - Namat, Dina Al
A10 - Ghiciuc, Cristina
A11 - Lupusoru, Catalina Elena
A12 - Tinica, Grigore
A13 - Mitu, Florin
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2017
VL - 68
IS - 7
SP - 1485
EP - 1489
UR - https://doi.org/10.37358/RC.17.7.5701
KW - heart-type fatty acid binding protein
KW - coronary-artery bypass graft
KW - cardiac rehabilitation
ER -


BibTex
@article{RevCh2017P1485,
author = {Namat Razan Al and Aursulesei Viviana and Felea Maura Gabriela and Costache Irina Iuliana and Petris Antoniu and Mitu Ovidiu and Namat Nadia Al and Constantin Mihai and Namat Dina Al and Ghiciuc Cristina and Lupusoru Catalina Elena and Tinica Grigore and Mitu Florin},
title = {Heart-Type Fatty Acid-Binding Protein (H-FABP) in Patients with Coronary Artery Bypass Graft Surgery Undergoing Cardiac Rehabilitation Program},
journal = {Revista de Chimie},
volume = {68},
number = {7},
pages = {1485-1489},
year = {2017},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.17.7.5701},
url = {https://revistadechimie.ro/Articles.asp?ID=5701}
}
 
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