Adhesion and Secretory Profile of Mesenchymal Stem Cells Upon Contact with Some Biomaterials

Tatu, Carmen Sofica; Panaitescu, Carmen; Marusciac, Laura; Sisu, Alina Maria; Cristea, Mirabela; Puscasiu, Daniela Anca; Tanasie, Gabriela

Carmen Sofica Tatu, Carmen Panaitescu, Laura Marusciac, Alina Maria Sisu, Mirabela Cristea, Daniela Anca Puscasiu, Gabriela Tanasie

Adhesion and Secretory Profile of Mesenchymal Stem Cells Upon Contact with Some Biomaterials

Abstract:

The aim of this study was to investigate the adhesion and secretory profile of mesenchymal stem cells in contact with biomaterials used in the field of tissue engineering. Mesenchymal stem cells obtained from lipoaspirate and two biomaterials were used: anodized titanium plates coated with hydroxyapatite crystals and collagen meshes crosslinked with formic anhydride combined with poly(e-caprolactone). Cell adhesion capacity of the two types of biomaterials was assessed by counting non-adhering cells in the supernatant, and the secretory profile by ELISA dosing of a series of cytokines and growth factors released by the cells upon contact with the two biomaterials. Faster fixation of mesenchymal stem cells on titanium matrices compared to the collagen ones was observed. In contact with the materials, the mesenchymal stem cells alter their secretory phenotype, with a slight increase in their pro-inflammatory potential.

Keywords:
mesenchymal stem cells; biomaterials; adherence; secretory profile

Issue: 2017, Volume 68, Issue 9

Pages: 2079-2082

Publication date: 2017/10/15

https://doi.org/10.37358/RC.17.9.5827

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
TATU, C.S., PANAITESCU, C., MARUSCIAC, L., SISU, A.M., CRISTEA, M., PUSCASIU, D.A., TANASIE, G., Adhesion and Secretory Profile of Mesenchymal Stem Cells Upon Contact with Some Biomaterials, Rev. Chim., 68(9), 2017, 2079-2082.

Vancouver
Tatu CS, Panaitescu C, Marusciac L, Sisu AM, Cristea M, Puscasiu DA, Tanasie G. Adhesion and Secretory Profile of Mesenchymal Stem Cells Upon Contact with Some Biomaterials. Rev. Chim.[internet]. 2017 Sep;68(9):2079-2082. Available from: https://doi.org/10.37358/RC.17.9.5827

APA 6th edition
Tatu, C.S., Panaitescu, C., Marusciac, L., Sisu, A.M., Cristea, M., Puscasiu, D.A. & Tanasie, G. (2017). Adhesion and Secretory Profile of Mesenchymal Stem Cells Upon Contact with Some Biomaterials. Revista de Chimie, 68(9), 2079-2082. https://doi.org/10.37358/RC.17.9.5827

Harvard
Tatu, C.S., Panaitescu, C., Marusciac, L., Sisu, A.M., Cristea, M., Puscasiu, D.A., Tanasie, G. (2017). 'Adhesion and Secretory Profile of Mesenchymal Stem Cells Upon Contact with Some Biomaterials', Revista de Chimie, 68(9), pp. 2079-2082. https://doi.org/10.37358/RC.17.9.5827

IEEE
C.S. Tatu, C. Panaitescu, L. Marusciac, A.M. Sisu, M. Cristea, D.A. Puscasiu, G. Tanasie, "Adhesion and Secretory Profile of Mesenchymal Stem Cells Upon Contact with Some Biomaterials". Revista de Chimie, vol. 68, no. 9, pp. 2079-2082, 2017. [online]. https://doi.org/10.37358/RC.17.9.5827

Text
Carmen Sofica Tatu, Carmen Panaitescu, Laura Marusciac, Alina Maria Sisu, Mirabela Cristea, Daniela Anca Puscasiu, Gabriela Tanasie,
Adhesion and Secretory Profile of Mesenchymal Stem Cells Upon Contact with Some Biomaterials,
Revista de Chimie,
Volume 68, Issue 9,
2017,
Pages 2079-2082,
ISSN 2668-8212,
https://doi.org/10.37358/RC.17.9.5827.
(https://revistadechimie.ro/Articles.asp?ID=5827)
Keywords: mesenchymal stem cells; biomaterials; adherence; secretory profile

RIS
TY - JOUR
T1 - Adhesion and Secretory Profile of Mesenchymal Stem Cells Upon Contact with Some Biomaterials
A1 - Tatu, Carmen Sofica
A2 - Panaitescu, Carmen
A3 - Marusciac, Laura
A4 - Sisu, Alina Maria
A5 - Cristea, Mirabela
A6 - Puscasiu, Daniela Anca
A7 - Tanasie, Gabriela
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2017
VL - 68
IS - 9
SP - 2079
EP - 2082
UR - https://doi.org/10.37358/RC.17.9.5827
KW - mesenchymal stem cells
KW - biomaterials
KW - adherence
KW - secretory profile
ER -

BibTex
@article{RevCh2017P2079,
author = {Tatu Carmen Sofica and Panaitescu Carmen and Marusciac Laura and Sisu Alina Maria and Cristea Mirabela and Puscasiu Daniela Anca and Tanasie Gabriela},
title = {Adhesion and Secretory Profile of Mesenchymal Stem Cells Upon Contact with Some Biomaterials},
journal = {Revista de Chimie},
volume = {68},
number = {9},
pages = {2079-2082},
year = {2017},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.17.9.5827},
url = {https://revistadechimie.ro/Articles.asp?ID=5827}
}

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