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https://doi.org/10.37358/Rev.Chim.1949

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Revista de Chimie (Rev. Chim.), Year 2017, Volume 68, Issue 9, 2147-2150

https://doi.org/10.37358/RC.17.9.5844

Liliana Coldea, Florin Grosu, Alina Liliana Pintea, Sebastian Ioan Cernusca Mitariu, Nicolae Grigore, Raluca Monica Comaneanu, Corina Roman Filip

The Effects of Interferon and Ribavirin in Chronic Hepatite C

Abstract:

The chronic hepatitis C is a frequently problem in worldwide, the number of infected individuals is high and go on, getting a public health problem [1]. In Romania there are nearly 1 million persons infected with hepatitis C virus, the scope of spreading is related with specific risk factors. An important number of infection with hepatitis C virus present simultaneous extrahepatic manifestations proved to be alone manifestation tracing; its important for diagnosis and treatment. We analyzed the effects of interferon and ribavirin in chronic hepatitis C in General C.F. Hospital Sibiu, between 2008 - 2012. The association between infection with hepatitis C virus and extrahepatic manifestations is important to be recognized for adequate diagnosis tests. By comparing the results of therapy in patients with hepatic and extrahepatic manifestations, the study found that 30 patients (58.83 %) with liver manifestations had an incomplete response versus 10 patients (26.32 %) with extrahepatic manifestations; 11 patients (21.54 %) with hepatic manifestations had a complete response versus 3 patients (7.89 %) with extrahepatic manifestations; and 10 patients (19.63 %) with hepatic manifestations did not respond to treatment versus 25 patients (65.79 %) with extrahepatic manifestations. Analyzing the results of antiviral therapy in patients with hepatic manifestations and those with extrahepatic manifestations, antiviral treatment appears to be more advantageous in cases with only hepatic manifestations.
Keywords:
chronic hepatitis; hepatitis C virus; extrahepatic manifestations; interferon; ribavirin; treatment

Issue: 2017, Volume 68, Issue 9
Pages: 2147-2150
Publication date: 2017/10/15
https://doi.org/10.37358/RC.17.9.5844
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Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
COLDEA, L., GROSU, F., PINTEA, A.L., MITARIU, S.I.C., GRIGORE, N., COMANEANU, R.M., FILIP, C.R., The Effects of Interferon and Ribavirin in Chronic Hepatite C, Rev. Chim., 68(9), 2017, 2147-2150.

Vancouver
Coldea L, Grosu F, Pintea AL, Mitariu SIC, Grigore N, Comaneanu RM, Filip CR. The Effects of Interferon and Ribavirin in Chronic Hepatite C. Rev. Chim.[internet]. 2017 Sep;68(9):2147-2150. Available from: https://doi.org/10.37358/RC.17.9.5844


APA 6th edition
Coldea, L., Grosu, F., Pintea, A.L., Mitariu, S.I.C., Grigore, N., Comaneanu, R.M. & Filip, C.R. (2017). The Effects of Interferon and Ribavirin in Chronic Hepatite C. Revista de Chimie, 68(9), 2147-2150. https://doi.org/10.37358/RC.17.9.5844


Harvard
Coldea, L., Grosu, F., Pintea, A.L., Mitariu, S.I.C., Grigore, N., Comaneanu, R.M., Filip, C.R. (2017). 'The Effects of Interferon and Ribavirin in Chronic Hepatite C', Revista de Chimie, 68(9), pp. 2147-2150. https://doi.org/10.37358/RC.17.9.5844


IEEE
L. Coldea, F. Grosu, A.L. Pintea, S.I.C. Mitariu, N. Grigore, R.M. Comaneanu, C.R. Filip, "The Effects of Interferon and Ribavirin in Chronic Hepatite C". Revista de Chimie, vol. 68, no. 9, pp. 2147-2150, 2017. [online]. https://doi.org/10.37358/RC.17.9.5844


Text
Liliana Coldea, Florin Grosu, Alina Liliana Pintea, Sebastian Ioan Cernusca Mitariu, Nicolae Grigore, Raluca Monica Comaneanu, Corina Roman Filip,
The Effects of Interferon and Ribavirin in Chronic Hepatite C,
Revista de Chimie,
Volume 68, Issue 9,
2017,
Pages 2147-2150,
ISSN 2668-8212,
https://doi.org/10.37358/RC.17.9.5844.
(https://revistadechimie.ro/Articles.asp?ID=5844)
Keywords: chronic hepatitis; hepatitis C virus; extrahepatic manifestations; interferon; ribavirin; treatment


RIS
TY - JOUR
T1 - The Effects of Interferon and Ribavirin in Chronic Hepatite C
A1 - Coldea, Liliana
A2 - Grosu, Florin
A3 - Pintea, Alina Liliana
A4 - Mitariu, Sebastian Ioan Cernusca
A5 - Grigore, Nicolae
A6 - Comaneanu, Raluca Monica
A7 - Filip, Corina Roman
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2017
VL - 68
IS - 9
SP - 2147
EP - 2150
UR - https://doi.org/10.37358/RC.17.9.5844
KW - chronic hepatitis
KW - hepatitis C virus
KW - extrahepatic manifestations
KW - interferon
KW - ribavirin
KW - treatment
ER -


BibTex
@article{RevCh2017P2147,
author = {Coldea Liliana and Grosu Florin and Pintea Alina Liliana and Mitariu Sebastian Ioan Cernusca and Grigore Nicolae and Comaneanu Raluca Monica and Filip Corina Roman},
title = {The Effects of Interferon and Ribavirin in Chronic Hepatite C},
journal = {Revista de Chimie},
volume = {68},
number = {9},
pages = {2147-2150},
year = {2017},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.17.9.5844},
url = {https://revistadechimie.ro/Articles.asp?ID=5844}
}
 
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