Does Active Smoking Influence the Second Trimester Biochemical Markers Concentrations?

Navolan, Dan; Birsasteanu, Florin; Carabineanu, Adrian; Cretu, Octavian; Badiu, Diana Liana; Ionescu, Cringu Antoniu; Mehedintu, Claudia; Vladareanu, Simona; Craina, Marius; Boia, Marioara; Ciohat, Ioana; Craciunescu, Mihaela; Simu, Sebastian; Nemescu, Dragos

Dan Navolan, Florin Birsasteanu, Adrian Carabineanu, Octavian Cretu, Diana Liana Badiu, Cringu Antoniu Ionescu, Claudia Mehedintu, Simona Vladareanu, Marius Craina, Marioara Boia, Ioana Ciohat, Mihaela Craciunescu, Sebastian Simu, Dragos Nemescu

Does Active Smoking Influence the Second Trimester Biochemical Markers Concentrations?

Abstract:

Cigarette smoke contains over 7000 different substances some of them exerting harmful effects on embryo and pregnant woman. Nowadays 15 % of adult people and around 10-15% of pregnant women smoke. Previous studies showed that cigarette smoke compounds could exert pharmacodinamic effects and influence some of the second trimester biochemical markers concentration. Therefore there is a need to adjust the reference values of second trimester markers depending of the smoker status. The aim of our study was to analyse which of the markers are influenced by smoking and whether the software used to calculate the risk for aneuploidies is able to counterbalance this influence. Alpha-fetoprotein (AFP), chorionic gonadotropin hormone (hCG) and free estriol (uE3) values were measured in second trimester sera of 1242 pregnant women: 1089 non-smokers and 153 smokers. Only hCG second trimester values were influenced by smoking whereas AFP and uE3 values were not. The correction of medians according to the smoking status was able to counterbalance this effect.

Keywords:
second trimester biochemical markers; aneuploidies; smoking; correction

Issue: 2017, Volume 68, Issue 10

Pages: 2234-2236

Publication date: 2017/11/15

https://doi.org/10.37358/RC.17.10.5862

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
NAVOLAN, D., BIRSASTEANU, F., CARABINEANU, A., CRETU, O., BADIU, D.L., IONESCU, C.A., MEHEDINTU, C., VLADAREANU, S., CRAINA, M., BOIA, M., CIOHAT, I., CRACIUNESCU, M., SIMU, S., NEMESCU, D., Does Active Smoking Influence the Second Trimester Biochemical Markers Concentrations?, Rev. Chim., 68(10), 2017, 2234-2236.

Vancouver
Navolan D, Birsasteanu F, Carabineanu A, Cretu O, Badiu DL, Ionescu CA, Mehedintu C, Vladareanu S, Craina M, Boia M, Ciohat I, Craciunescu M, Simu S, Nemescu D. Does Active Smoking Influence the Second Trimester Biochemical Markers Concentrations?. Rev. Chim.[internet]. 2017 Oct;68(10):2234-2236. Available from: https://doi.org/10.37358/RC.17.10.5862

APA 6th edition
Navolan, D., Birsasteanu, F., Carabineanu, A., Cretu, O., Badiu, D.L., Ionescu, C.A.,... Nemescu, D. (2017). Does Active Smoking Influence the Second Trimester Biochemical Markers Concentrations?. Revista de Chimie, 68(10), 2234-2236. https://doi.org/10.37358/RC.17.10.5862

Harvard
Navolan, D., Birsasteanu, F., Carabineanu, A., Cretu, O., Badiu, D.L., Ionescu, C.A., Mehedintu, C., Vladareanu, S., Craina, M., Boia, M., Ciohat, I., Craciunescu, M., Simu, S., Nemescu, D. (2017). 'Does Active Smoking Influence the Second Trimester Biochemical Markers Concentrations?', Revista de Chimie, 68(10), pp. 2234-2236. https://doi.org/10.37358/RC.17.10.5862

IEEE
D. Navolan, F. Birsasteanu, A. Carabineanu, O. Cretu, D.L. Badiu, C.A. Ionescu, C. Mehedintu, S. Vladareanu, M. Craina, M. Boia, I. Ciohat, M. Craciunescu, S. Simu, D. Nemescu, "Does Active Smoking Influence the Second Trimester Biochemical Markers Concentrations?". Revista de Chimie, vol. 68, no. 10, pp. 2234-2236, 2017. [online]. https://doi.org/10.37358/RC.17.10.5862

Text
Dan Navolan, Florin Birsasteanu, Adrian Carabineanu, Octavian Cretu, Diana Liana Badiu, Cringu Antoniu Ionescu, Claudia Mehedintu, Simona Vladareanu, Marius Craina, Marioara Boia, Ioana Ciohat, Mihaela Craciunescu, Sebastian Simu, Dragos Nemescu,
Does Active Smoking Influence the Second Trimester Biochemical Markers Concentrations?,
Revista de Chimie,
Volume 68, Issue 10,
2017,
Pages 2234-2236,
ISSN 2668-8212,
https://doi.org/10.37358/RC.17.10.5862.
(https://revistadechimie.ro/Articles.asp?ID=5862)
Keywords: second trimester biochemical markers; aneuploidies; smoking; correction

RIS
TY - JOUR
T1 - Does Active Smoking Influence the Second Trimester Biochemical Markers Concentrations?
A1 - Navolan, Dan
A2 - Birsasteanu, Florin
A3 - Carabineanu, Adrian
A4 - Cretu, Octavian
A5 - Badiu, Diana Liana
A6 - Ionescu, Cringu Antoniu
A7 - Mehedintu, Claudia
A8 - Vladareanu, Simona
A9 - Craina, Marius
A10 - Boia, Marioara
A11 - Ciohat, Ioana
A12 - Craciunescu, Mihaela
A13 - Simu, Sebastian
A14 - Nemescu, Dragos
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2017
VL - 68
IS - 10
SP - 2234
EP - 2236
UR - https://doi.org/10.37358/RC.17.10.5862
KW - second trimester biochemical markers
KW - aneuploidies
KW - smoking
KW - correction
ER -

BibTex
@article{RevCh2017P2234,
author = {Navolan Dan and Birsasteanu Florin and Carabineanu Adrian and Cretu Octavian and Badiu Diana Liana and Ionescu Cringu Antoniu and Mehedintu Claudia and Vladareanu Simona and Craina Marius and Boia Marioara and Ciohat Ioana and Craciunescu Mihaela and Simu Sebastian and Nemescu Dragos},
title = {Does Active Smoking Influence the Second Trimester Biochemical Markers Concentrations?},
journal = {Revista de Chimie},
volume = {68},
number = {10},
pages = {2234-2236},
year = {2017},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.17.10.5862},
url = {https://revistadechimie.ro/Articles.asp?ID=5862}
}

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