The Role of the Immunohistochemical Examination in the Diagnosis of Castleman's Disease

Badulescu, Oana Viola; Hultoana, Roxana; Ciuntu, Bogdan Mihnea; Papancea, Adelina; Georgescu, Stefan Octavian

Oana Viola Badulescu, Roxana Hultoana, Bogdan Mihnea Ciuntu, Adelina Papancea, Stefan Octavian Georgescu

The Role of the Immunohistochemical Examination in the Diagnosis of Castleman's Disease

Abstract:

Castleman’s disease is characterized by benign angiolymphoid hyperplasia. There are two clinical forms: the localized form in which one lymph node is affected, often paucisimptomatic, treated by radical surgical excision, without recurrence in most cases, and the multicentric form, characterized by systemic manifestations, polyadenopathy (mediastin, cervical region, abdomen, etc.) , organomegaly (e.g. spleen, liver), with a less favorable prognosis than the localized form. The etiology of the disease remains unknown; recent studies suggest the implication of human herpes virus 8 (HHV-8), especially in multicenter forms. We shall present the case of women, aged 23, with Castleman’s disease with retroperitoneal localization, who was admitted to the surgery clinic due to abdominal pains. The initial abdominal CT raised the suspicion of a hepatic lobus caudatus tumor, but the anatomical-pathological result confirmed the diagnosis of angiofolicular hyperplasia of the lymph nodes. Diagnostic methods, histological forms, treatment and prognosis aspects of Castleman’s disease are described below.

Keywords:
Castleman’s disease; retroperitoneal hyperplasia; liver tumor

Issue: 2017, Volume 68, Issue 11

Pages: 2685-2686

Publication date: 2017/12/15

https://doi.org/10.37358/RC.17.11.5954

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
BADULESCU, O.V., HULTOANA, R., CIUNTU, B.M., PAPANCEA, A., GEORGESCU, S.O., The Role of the Immunohistochemical Examination in the Diagnosis of Castleman's Disease, Rev. Chim., 68(11), 2017, 2685-2686.

Vancouver
Badulescu OV, Hultoana R, Ciuntu BM, Papancea A, Georgescu SO. The Role of the Immunohistochemical Examination in the Diagnosis of Castleman's Disease. Rev. Chim.[internet]. 2017 Nov;68(11):2685-2686. Available from: https://doi.org/10.37358/RC.17.11.5954

APA 6th edition
Badulescu, O.V., Hultoana, R., Ciuntu, B.M., Papancea, A. & Georgescu, S.O. (2017). The Role of the Immunohistochemical Examination in the Diagnosis of Castleman's Disease. Revista de Chimie, 68(11), 2685-2686. https://doi.org/10.37358/RC.17.11.5954

Harvard
Badulescu, O.V., Hultoana, R., Ciuntu, B.M., Papancea, A., Georgescu, S.O. (2017). 'The Role of the Immunohistochemical Examination in the Diagnosis of Castleman's Disease', Revista de Chimie, 68(11), pp. 2685-2686. https://doi.org/10.37358/RC.17.11.5954

IEEE
O.V. Badulescu, R. Hultoana, B.M. Ciuntu, A. Papancea, S.O. Georgescu, "The Role of the Immunohistochemical Examination in the Diagnosis of Castleman's Disease". Revista de Chimie, vol. 68, no. 11, pp. 2685-2686, 2017. [online]. https://doi.org/10.37358/RC.17.11.5954

Text
Oana Viola Badulescu, Roxana Hultoana, Bogdan Mihnea Ciuntu, Adelina Papancea, Stefan Octavian Georgescu,
The Role of the Immunohistochemical Examination in the Diagnosis of Castleman's Disease,
Revista de Chimie,
Volume 68, Issue 11,
2017,
Pages 2685-2686,
ISSN 2668-8212,
https://doi.org/10.37358/RC.17.11.5954.
(https://revistadechimie.ro/Articles.asp?ID=5954)
Keywords: Castleman’s disease; retroperitoneal hyperplasia; liver tumor

RIS
TY - JOUR
T1 - The Role of the Immunohistochemical Examination in the Diagnosis of Castleman's Disease
A1 - Badulescu, Oana Viola
A2 - Hultoana, Roxana
A3 - Ciuntu, Bogdan Mihnea
A4 - Papancea, Adelina
A5 - Georgescu, Stefan Octavian
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2017
VL - 68
IS - 11
SP - 2685
EP - 2686
UR - https://doi.org/10.37358/RC.17.11.5954
KW - Castleman’s disease
KW - retroperitoneal hyperplasia
KW - liver tumor
ER -

BibTex
@article{RevCh2017P2685,
author = {Badulescu Oana Viola and Hultoana Roxana and Ciuntu Bogdan Mihnea and Papancea Adelina and Georgescu Stefan Octavian},
title = {The Role of the Immunohistochemical Examination in the Diagnosis of Castleman's Disease},
journal = {Revista de Chimie},
volume = {68},
number = {11},
pages = {2685-2686},
year = {2017},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.17.11.5954},
url = {https://revistadechimie.ro/Articles.asp?ID=5954}
}

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