Methylene blue staining test in assessing safe margins in laryngeal papillomatosis

Hainarosie, Razvan; Pituru, Silviu; Stefanescu, Dragos Cristian; Hainarosie, Mura; Ionita, Irina; Pietrosanu, Catalina; Ionut, Mircea Gheorghita; Zainea, Viorel

Razvan Hainarosie, Silviu Pituru, Dragos Cristian Stefanescu, Mura Hainarosie, Irina Ionita, Catalina Pietrosanu, Mircea Gheorghita Ionut, Viorel Zainea

Methylene blue staining test in assessing safe margins in laryngeal papillomatosis

Abstract:

Laryngeal papillomatosis, although a viral and benign disease, poses a great challenge for the ENT surgeon from a therapeutical point of view. The lack of a curative treatment and the tendency of the papillomatosis to recur in an extensive manner require an aggressive treatment. Although multiple medical therapies are available, their results are not always the desired ones. That is why nowadays the focus of the therapy is on the surgical approach. The best results may be obtained thru multiple surgeries, with resection of all papilloma foci. Although this approach may impact the quality of life of the patients due to the multiple interventions required, the overall result translates into a physiologic airway. Because the site where the lesions first appear is at an epithelial level, tendency to use methods of early diagnosis, that make the disease recognizable before extensive lesions, is the natural tendency. Also, it is extremely important to remove all papilloma lesions during surgery, thus minimizing the chances of recurrence or at least increasing the interval between interventions.The aim of this paper is to present the methylene blue staining test as an adjuvant method of evaluating the resection margins during surgery for laryngeal papillomatosis. This method can improve the results of surgery and increase the patient’s adherence to treatment, by decreasing the number of interventions required.

Keywords:
methylene blue; laryngeal papillomatosis; safe margins; surgery

Issue: 2017, Volume 68, Issue 11

Pages: 2731-2733

Publication date: 2017/12/15

https://doi.org/10.37358/RC.17.11.5964

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
HAINAROSIE, R., PITURU, S., STEFANESCU, D.C., HAINAROSIE, M., IONITA, I., PIETROSANU, C., IONUT, M.G., ZAINEA, V., Methylene blue staining test in assessing safe margins in laryngeal papillomatosis, Rev. Chim., 68(11), 2017, 2731-2733.

Vancouver
Hainarosie R, Pituru S, Stefanescu DC, Hainarosie M, Ionita I, Pietrosanu C, Ionut MG, Zainea V. Methylene blue staining test in assessing safe margins in laryngeal papillomatosis. Rev. Chim.[internet]. 2017 Nov;68(11):2731-2733. Available from: https://doi.org/10.37358/RC.17.11.5964

APA 6th edition
Hainarosie, R., Pituru, S., Stefanescu, D.C., Hainarosie, M., Ionita, I., Pietrosanu, C., Ionut, M.G. & Zainea, V. (2017). Methylene blue staining test in assessing safe margins in laryngeal papillomatosis. Revista de Chimie, 68(11), 2731-2733. https://doi.org/10.37358/RC.17.11.5964

Harvard
Hainarosie, R., Pituru, S., Stefanescu, D.C., Hainarosie, M., Ionita, I., Pietrosanu, C., Ionut, M.G., Zainea, V. (2017). 'Methylene blue staining test in assessing safe margins in laryngeal papillomatosis', Revista de Chimie, 68(11), pp. 2731-2733. https://doi.org/10.37358/RC.17.11.5964

IEEE
R. Hainarosie, S. Pituru, D.C. Stefanescu, M. Hainarosie, I. Ionita, C. Pietrosanu, M.G. Ionut, V. Zainea, "Methylene blue staining test in assessing safe margins in laryngeal papillomatosis". Revista de Chimie, vol. 68, no. 11, pp. 2731-2733, 2017. [online]. https://doi.org/10.37358/RC.17.11.5964

Text
Razvan Hainarosie, Silviu Pituru, Dragos Cristian Stefanescu, Mura Hainarosie, Irina Ionita, Catalina Pietrosanu, Mircea Gheorghita Ionut, Viorel Zainea,
Methylene blue staining test in assessing safe margins in laryngeal papillomatosis,
Revista de Chimie,
Volume 68, Issue 11,
2017,
Pages 2731-2733,
ISSN 2668-8212,
https://doi.org/10.37358/RC.17.11.5964.
(https://revistadechimie.ro/Articles.asp?ID=5964)
Keywords: methylene blue; laryngeal papillomatosis; safe margins; surgery

RIS
TY - JOUR
T1 - Methylene blue staining test in assessing safe margins in laryngeal papillomatosis
A1 - Hainarosie, Razvan
A2 - Pituru, Silviu
A3 - Stefanescu, Dragos Cristian
A4 - Hainarosie, Mura
A5 - Ionita, Irina
A6 - Pietrosanu, Catalina
A7 - Ionut, Mircea Gheorghita
A8 - Zainea, Viorel
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2017
VL - 68
IS - 11
SP - 2731
EP - 2733
UR - https://doi.org/10.37358/RC.17.11.5964
KW - methylene blue
KW - laryngeal papillomatosis
KW - safe margins
KW - surgery
ER -

BibTex
@article{RevCh2017P2731,
author = {Hainarosie Razvan and Pituru Silviu and Stefanescu Dragos Cristian and Hainarosie Mura and Ionita Irina and Pietrosanu Catalina and Ionut Mircea Gheorghita and Zainea Viorel},
title = {Methylene blue staining test in assessing safe margins in laryngeal papillomatosis},
journal = {Revista de Chimie},
volume = {68},
number = {11},
pages = {2731-2733},
year = {2017},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.17.11.5964},
url = {https://revistadechimie.ro/Articles.asp?ID=5964}
}

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