The Use of Lugol Test in Determining the CSF Leaks Location of the Anterior Skull Base

Hainarosie, Razvan; Meius, Alexandru; Ionita, Irina; Hainarosie, Mura; Stefanescu, Cristian Dragos; Zainea, Viorel; Pietrosanu, Catalina

Razvan Hainarosie, Alexandru Meius, Irina Ionita, Mura Hainarosie, Cristian Dragos Stefanescu, Viorel Zainea, Catalina Pietrosanu

The Use of Lugol Test in Determining the CSF Leaks Location of the Anterior Skull Base

Abstract:

Cerebrospinal fluid rhinorrhea is a rare medical problem but with increased mortality potential due to the risk of meningitis. This condition can be either traumatic or nontraumatic, based on the etiology. The traumatic CSF fistulas represent almost 80% of the entire CSF fistulas, surgical procedures cause nearly 16% of the CSF leaks in the anterior skull base, and the nontraumatic CSF leaks represent only 4%, and they are divided in normal-pressure and high-pressure fistulas. The diagnosis of CSF leaks is made by demonstrating the evidence of extracranial CSF. The diagnostic methods are double ring sign, glucose content of the nasal fluid, Beta-trace protein test, Beta2-transferrin test. To eliminate this risk of meningitis, when a CSF leak is discovered, the defect must be closed surgically. The challenge is to determine the exact location of the defect, mainly in cases of spontaneous CSF fistulas. The imagistic examination consists of CT scans and MRI tests. The gold standard for detecting CSF leakage is still intrathecal injection of fluorescein with endoscopic localization of the dural defect. This paper aims to analyze a staining test, using Lugol solution, to detect the location of the CSF fistula. The Lugol staining test that we proposed is quick, cheap, it does not produce a toxic reaction, excepting the Iodine allergic patients, and it can be used to detect the location of the skull base defect and the CSF leak.

Keywords:
CSF fistula; Lugol staining test; cerebrospinal fluid rhinorrhea

Issue: 2018, Volume 69, Issue 2

Pages: 400-402

Publication date: 2018/3/15

https://doi.org/10.37358/RC.18.2.6115

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
HAINAROSIE, R., MEIUS, A., IONITA, I., HAINAROSIE, M., STEFANESCU, C.D., ZAINEA, V., PIETROSANU, C., The Use of Lugol Test in Determining the CSF Leaks Location of the Anterior Skull Base, Rev. Chim., 69(2), 2018, 400-402.

Vancouver
Hainarosie R, Meius A, Ionita I, Hainarosie M, Stefanescu CD, Zainea V, Pietrosanu C. The Use of Lugol Test in Determining the CSF Leaks Location of the Anterior Skull Base. Rev. Chim.[internet]. 2018 Feb;69(2):400-402. Available from: https://doi.org/10.37358/RC.18.2.6115

APA 6th edition
Hainarosie, R., Meius, A., Ionita, I., Hainarosie, M., Stefanescu, C.D., Zainea, V. & Pietrosanu, C. (2018). The Use of Lugol Test in Determining the CSF Leaks Location of the Anterior Skull Base. Revista de Chimie, 69(2), 400-402. https://doi.org/10.37358/RC.18.2.6115

Harvard
Hainarosie, R., Meius, A., Ionita, I., Hainarosie, M., Stefanescu, C.D., Zainea, V., Pietrosanu, C. (2018). 'The Use of Lugol Test in Determining the CSF Leaks Location of the Anterior Skull Base', Revista de Chimie, 69(2), pp. 400-402. https://doi.org/10.37358/RC.18.2.6115

IEEE
R. Hainarosie, A. Meius, I. Ionita, M. Hainarosie, C.D. Stefanescu, V. Zainea, C. Pietrosanu, "The Use of Lugol Test in Determining the CSF Leaks Location of the Anterior Skull Base". Revista de Chimie, vol. 69, no. 2, pp. 400-402, 2018. [online]. https://doi.org/10.37358/RC.18.2.6115

Text
Razvan Hainarosie, Alexandru Meius, Irina Ionita, Mura Hainarosie, Cristian Dragos Stefanescu, Viorel Zainea, Catalina Pietrosanu,
The Use of Lugol Test in Determining the CSF Leaks Location of the Anterior Skull Base,
Revista de Chimie,
Volume 69, Issue 2,
2018,
Pages 400-402,
ISSN 2668-8212,
https://doi.org/10.37358/RC.18.2.6115.
(https://revistadechimie.ro/Articles.asp?ID=6115)
Keywords: CSF fistula; Lugol staining test; cerebrospinal fluid rhinorrhea

RIS
TY - JOUR
T1 - The Use of Lugol Test in Determining the CSF Leaks Location of the Anterior Skull Base
A1 - Hainarosie, Razvan
A2 - Meius, Alexandru
A3 - Ionita, Irina
A4 - Hainarosie, Mura
A5 - Stefanescu, Cristian Dragos
A6 - Zainea, Viorel
A7 - Pietrosanu, Catalina
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2018
VL - 69
IS - 2
SP - 400
EP - 402
UR - https://doi.org/10.37358/RC.18.2.6115
KW - CSF fistula
KW - Lugol staining test
KW - cerebrospinal fluid rhinorrhea
ER -

BibTex
@article{RevCh2018P400,
author = {Hainarosie Razvan and Meius Alexandru and Ionita Irina and Hainarosie Mura and Stefanescu Cristian Dragos and Zainea Viorel and Pietrosanu Catalina},
title = {The Use of Lugol Test in Determining the CSF Leaks Location of the Anterior Skull Base},
journal = {Revista de Chimie},
volume = {69},
number = {2},
pages = {400-402},
year = {2018},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.18.2.6115},
url = {https://revistadechimie.ro/Articles.asp?ID=6115}
}

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