Iodinated Contrast Media in Pediatric Cardiac Angiography Nephrotoxic risk evaluation

Cinteza, Eliza; Balgradean, Mihaela; Filip, Cristina; Duica, Gabriela; Nicolae, Georgiana; Nicolescu, Alin; Mahmoud, Hyam

Eliza Cinteza, Mihaela Balgradean, Cristina Filip, Gabriela Duica, Georgiana Nicolae, Alin Nicolescu, Hyam Mahmoud

Iodinated Contrast Media in Pediatric Cardiac Angiography Nephrotoxic risk evaluation

Abstract:

Contrast agents are among the most frequently used drugs in medical practice. The aim of our study was to evaluate the incidence of complications associated with the use of different contrast agents in an angiography lab dedicated to pediatric patients with congenital heart disease. Between June 2015 and December 2017, 166 patients with congenital heart disease were diagnosed and/or treated in the angiography lab. Of these patients, 38 were excluded because they did not require contrast substance administration. As interventional procedures we performed pulmonary valvular dilatation in 17 cases (10.2%), stent implantation in coarctation of the aorta in 9 cases (5.4%), PDA closure in 62 cases (37.3%), atrial septal defect (ASD) closure in 36 patients (including patients without contrast agent’s administration) (21.7%). In the group of 129 patients who received contrast agents, the median age was 5.8 years (range 0.1-19 years) and median weight 22.8 kg (range 2.8-72 kg). Average consumption of contrast media per procedure was 79 ml/procedure (range 5 - 400 mL) and 4.3 mL/kg (range 0.4 - 22.7). We used iomeprol (24%), iohexol (8.5%), iopromide (67.4%). No contrast related complications are reported in this group. In conclusion, the contrast agents we used seem to be safe and are not associated with renal complications.

Keywords:
contrast-induced nephropathy; contrast-induced acute kidney injury; nephrotoxicity; contrast media; congenital heart disease; cardiac angiography

Issue: 2018, Volume 69, Issue 2

Pages: 511-514

Publication date: 2018/3/15

https://doi.org/10.37358/RC.18.2.6137

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
CINTEZA, E., BALGRADEAN, M., FILIP, C., DUICA, G., NICOLAE, G., NICOLESCU, A., MAHMOUD, H., Iodinated Contrast Media in Pediatric Cardiac Angiography Nephrotoxic risk evaluation, Rev. Chim., 69(2), 2018, 511-514.

Vancouver
Cinteza E, Balgradean M, Filip C, Duica G, Nicolae G, Nicolescu A, Mahmoud H. Iodinated Contrast Media in Pediatric Cardiac Angiography Nephrotoxic risk evaluation. Rev. Chim.[internet]. 2018 Feb;69(2):511-514. Available from: https://doi.org/10.37358/RC.18.2.6137

APA 6th edition
Cinteza, E., Balgradean, M., Filip, C., Duica, G., Nicolae, G., Nicolescu, A. & Mahmoud, H. (2018). Iodinated Contrast Media in Pediatric Cardiac Angiography Nephrotoxic risk evaluation. Revista de Chimie, 69(2), 511-514. https://doi.org/10.37358/RC.18.2.6137

Harvard
Cinteza, E., Balgradean, M., Filip, C., Duica, G., Nicolae, G., Nicolescu, A., Mahmoud, H. (2018). 'Iodinated Contrast Media in Pediatric Cardiac Angiography Nephrotoxic risk evaluation', Revista de Chimie, 69(2), pp. 511-514. https://doi.org/10.37358/RC.18.2.6137

IEEE
E. Cinteza, M. Balgradean, C. Filip, G. Duica, G. Nicolae, A. Nicolescu, H. Mahmoud, "Iodinated Contrast Media in Pediatric Cardiac Angiography Nephrotoxic risk evaluation". Revista de Chimie, vol. 69, no. 2, pp. 511-514, 2018. [online]. https://doi.org/10.37358/RC.18.2.6137

Text
Eliza Cinteza, Mihaela Balgradean, Cristina Filip, Gabriela Duica, Georgiana Nicolae, Alin Nicolescu, Hyam Mahmoud,
Iodinated Contrast Media in Pediatric Cardiac Angiography Nephrotoxic risk evaluation,
Revista de Chimie,
Volume 69, Issue 2,
2018,
Pages 511-514,
ISSN 2668-8212,
https://doi.org/10.37358/RC.18.2.6137.
(https://revistadechimie.ro/Articles.asp?ID=6137)
Keywords: contrast-induced nephropathy; contrast-induced acute kidney injury; nephrotoxicity; contrast media; congenital heart disease; cardiac angiography

RIS
TY - JOUR
T1 - Iodinated Contrast Media in Pediatric Cardiac Angiography Nephrotoxic risk evaluation
A1 - Cinteza, Eliza
A2 - Balgradean, Mihaela
A3 - Filip, Cristina
A4 - Duica, Gabriela
A5 - Nicolae, Georgiana
A6 - Nicolescu, Alin
A7 - Mahmoud, Hyam
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2018
VL - 69
IS - 2
SP - 511
EP - 514
UR - https://doi.org/10.37358/RC.18.2.6137
KW - contrast-induced nephropathy
KW - contrast-induced acute kidney injury
KW - nephrotoxicity
KW - contrast media
KW - congenital heart disease
KW - cardiac angiography
ER -

BibTex
@article{RevCh2018P511,
author = {Cinteza Eliza and Balgradean Mihaela and Filip Cristina and Duica Gabriela and Nicolae Georgiana and Nicolescu Alin and Mahmoud Hyam},
title = {Iodinated Contrast Media in Pediatric Cardiac Angiography Nephrotoxic risk evaluation},
journal = {Revista de Chimie},
volume = {69},
number = {2},
pages = {511-514},
year = {2018},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.18.2.6137},
url = {https://revistadechimie.ro/Articles.asp?ID=6137}
}

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