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https://doi.org/10.37358/Rev.Chim.1949

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Revista de Chimie (Rev. Chim.), Year 2018, Volume 69, Issue 4, 894-900

https://doi.org/10.37358/RC.18.4.6223

Pal Fodor, Raluca Fodor, Arpad Solyom, Cornel Catoi, Flaviu Tabaran, Radu Lacatus, Cristian Trambitas, Bogdan Cordos, Tiberiu Bataga

Autologous Matrix-Induced Chondrogenesis vs Microfracture with PRP for Chondral Lesions of the Knee in a Rabbit Model

Abstract:

Currently, microfracturing is the most commonly used cartilage repair procedure in cartilage defects. Our aim was to study the mechanism of in vivo cartilage repair in case of full-thickness articular cartilage damage of the knee using a three-dimensional matrix implanted without any preseeded cells in the defect. We also investigated whether platelet-rich plasma application after microfracture procedure of the knee is associated with improved outcome compared with traditional microfracture treatment alone in a rabbit model. Histological examination of the chondral defects, revealed the largest amount of new tissue with hyaline-like cartilage features in Hyalofast group. At 12 weeks from implantation of the Hyalofast scaffold demonstrated complete filling of the defect with hyaline cartilage in admixture with the scaffold and bone metaplasia in the deepest areas. In the PRP group, complete filling of the defect with an admixture of fibrous and hyaline-like cartilage tissue appeared with a discreet tendency of endochondral ossification. We confirmed the superiority of the autologous matrix-induced chondrogenesis compared to microfracture and PRP or microfracture alone in case of full-thickness articular cartilage damage of the knee.
Keywords:
autologous matrix-induced chondrogenesis; hyaline cartilage; microfracture; platelet-rich plasma

Issue: 2018, Volume 69, Issue 4
Pages: 894-900
Publication date: 2018/5/15
https://doi.org/10.37358/RC.18.4.6223
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Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
FODOR, P., FODOR, R., SOLYOM, A., CATOI, C., TABARAN, F., LACATUS, R., TRAMBITAS, C., CORDOS, B., BATAGA, T., Autologous Matrix-Induced Chondrogenesis vs Microfracture with PRP for Chondral Lesions of the Knee in a Rabbit Model, Rev. Chim., 69(4), 2018, 894-900.

Vancouver
Fodor P, Fodor R, Solyom A, Catoi C, Tabaran F, Lacatus R, Trambitas C, Cordos B, Bataga T. Autologous Matrix-Induced Chondrogenesis vs Microfracture with PRP for Chondral Lesions of the Knee in a Rabbit Model. Rev. Chim.[internet]. 2018 Apr;69(4):894-900. Available from: https://doi.org/10.37358/RC.18.4.6223


APA 6th edition
Fodor, P., Fodor, R., Solyom, A., Catoi, C., Tabaran, F., Lacatus, R.,... Bataga, T. (2018). Autologous Matrix-Induced Chondrogenesis vs Microfracture with PRP for Chondral Lesions of the Knee in a Rabbit Model. Revista de Chimie, 69(4), 894-900. https://doi.org/10.37358/RC.18.4.6223


Harvard
Fodor, P., Fodor, R., Solyom, A., Catoi, C., Tabaran, F., Lacatus, R., Trambitas, C., Cordos, B., Bataga, T. (2018). 'Autologous Matrix-Induced Chondrogenesis vs Microfracture with PRP for Chondral Lesions of the Knee in a Rabbit Model', Revista de Chimie, 69(4), pp. 894-900. https://doi.org/10.37358/RC.18.4.6223


IEEE
P. Fodor, R. Fodor, A. Solyom, C. Catoi, F. Tabaran, R. Lacatus, C. Trambitas, B. Cordos, T. Bataga, "Autologous Matrix-Induced Chondrogenesis vs Microfracture with PRP for Chondral Lesions of the Knee in a Rabbit Model". Revista de Chimie, vol. 69, no. 4, pp. 894-900, 2018. [online]. https://doi.org/10.37358/RC.18.4.6223


Text
Pal Fodor, Raluca Fodor, Arpad Solyom, Cornel Catoi, Flaviu Tabaran, Radu Lacatus, Cristian Trambitas, Bogdan Cordos, Tiberiu Bataga,
Autologous Matrix-Induced Chondrogenesis vs Microfracture with PRP for Chondral Lesions of the Knee in a Rabbit Model,
Revista de Chimie,
Volume 69, Issue 4,
2018,
Pages 894-900,
ISSN 2668-8212,
https://doi.org/10.37358/RC.18.4.6223.
(https://revistadechimie.ro/Articles.asp?ID=6223)
Keywords: autologous matrix-induced chondrogenesis; hyaline cartilage; microfracture; platelet-rich plasma


RIS
TY - JOUR
T1 - Autologous Matrix-Induced Chondrogenesis vs Microfracture with PRP for Chondral Lesions of the Knee in a Rabbit Model
A1 - Fodor, Pal
A2 - Fodor, Raluca
A3 - Solyom, Arpad
A4 - Catoi, Cornel
A5 - Tabaran, Flaviu
A6 - Lacatus, Radu
A7 - Trambitas, Cristian
A8 - Cordos, Bogdan
A9 - Bataga, Tiberiu
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2018
VL - 69
IS - 4
SP - 894
EP - 900
UR - https://doi.org/10.37358/RC.18.4.6223
KW - autologous matrix-induced chondrogenesis
KW - hyaline cartilage
KW - microfracture
KW - platelet-rich plasma
ER -


BibTex
@article{RevCh2018P894,
author = {Fodor Pal and Fodor Raluca and Solyom Arpad and Catoi Cornel and Tabaran Flaviu and Lacatus Radu and Trambitas Cristian and Cordos Bogdan and Bataga Tiberiu},
title = {Autologous Matrix-Induced Chondrogenesis vs Microfracture with PRP for Chondral Lesions of the Knee in a Rabbit Model},
journal = {Revista de Chimie},
volume = {69},
number = {4},
pages = {894-900},
year = {2018},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.18.4.6223},
url = {https://revistadechimie.ro/Articles.asp?ID=6223}
}
 
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