Renal Dysfunction - a Possible Marker of Severity of Heart Failure

Zaharie, Mirela; Carstea, Doina; Streba, Costin Teodor; Mitrut, Paul; Glodeanu, Adina Dorina; Carstea, Andrei Puiu; Zaharie, Sorin Ioan; Dascalu, Ionela Teodora; Tuculina, Mihaela Jana; Bunget, Adina; Bataiosu, Marilena; Ionovici, Nina

Mirela Zaharie, Doina Carstea, Costin Teodor Streba, Paul Mitrut, Adina Dorina Glodeanu, Andrei Puiu Carstea, Sorin Ioan Zaharie, Ionela Teodora Dascalu, Mihaela Jana Tuculina, Adina Bunget, Marilena Bataiosu, Nina Ionovici

Renal Dysfunction - a Possible Marker of Severity of Heart Failure

Abstract:

Heart failure (HF) and renal dysfunction are frequent associated in the same patient. The purpose of our study was to assess the prevalence of renal dysfunction and the clinical status in admitted patients for decompensated HF. Material and Methods. 397 patients succesively hospitalized for decompensated HF, NYHA III or IV functional class, with left ventricular ejection fraction (LVEF) £ 45% were included in the study. Renal dysfunction was defined by glomerular filtration rate (GFR) [ 60 mL/min/1.73 m 2. The mean GFR in patients with HF was 63.89 ± 21.5 mL/min/1.73 m2 .The prevalence of renal dysfunction was 49.6%. Patients with GFR [ 60 mL/min/1.73m2, compared with those with preserved renal function were significantly more frequent older (75.37 ± 6.84 vs. 71.33 ± 8.08 years; p [0.001), females (53,8% vs. 43.5%; p = 0.04), had a significantly higher prevalence of diabetes mellitus (50.2% vs. 28.5%; p [0.001), atrial fibrillation (53.8% vs 46.2%, p = 0.04) and anemia (47.7% vs. 29.5% ; p [0.001). Also, patients with renal dysfunction had more severe HF than those without renal dysfunction (NYHA class IV: 65% vs 45%, p [0.001, clinical congestion: 78.2% vs 68%, p = 0.02, LVEF [35%: 47.21% vs ³ 35%, p [0.001). Renal dysfunction can be considered an additional marker of severe cardiac dysfunction along with NYHA IV class and low LVEF. The presence of both renal dysfunction and anemia could represent prognostic markers in HF patients with reduced LVEF.

Keywords:
renal dysfunction; heart failure; anemia

Issue: 2018, Volume 69, Issue 6

Pages: 1435-1440

Publication date: 2018/7/15

https://doi.org/10.37358/RC.18.6.6341

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
ZAHARIE, M., CARSTEA, D., STREBA, C.T., MITRUT, P., GLODEANU, A.D., CARSTEA, A.P., ZAHARIE, S.I., DASCALU, I.T., TUCULINA, M.J., BUNGET, A., BATAIOSU, M., IONOVICI, N., Renal Dysfunction - a Possible Marker of Severity of Heart Failure, Rev. Chim., 69(6), 2018, 1435-1440.

Vancouver
Zaharie M, Carstea D, Streba CT, Mitrut P, Glodeanu AD, Carstea AP, Zaharie SI, Dascalu IT, Tuculina MJ, Bunget A, Bataiosu M, Ionovici N. Renal Dysfunction - a Possible Marker of Severity of Heart Failure. Rev. Chim.[internet]. 2018 Jun;69(6):1435-1440. Available from: https://doi.org/10.37358/RC.18.6.6341

APA 6th edition
Zaharie, M., Carstea, D., Streba, C.T., Mitrut, P., Glodeanu, A.D., Carstea, A.P.,... Ionovici, N. (2018). Renal Dysfunction - a Possible Marker of Severity of Heart Failure. Revista de Chimie, 69(6), 1435-1440. https://doi.org/10.37358/RC.18.6.6341

Harvard
Zaharie, M., Carstea, D., Streba, C.T., Mitrut, P., Glodeanu, A.D., Carstea, A.P., Zaharie, S.I., Dascalu, I.T., Tuculina, M.J., Bunget, A., Bataiosu, M., Ionovici, N. (2018). 'Renal Dysfunction - a Possible Marker of Severity of Heart Failure', Revista de Chimie, 69(6), pp. 1435-1440. https://doi.org/10.37358/RC.18.6.6341

IEEE
M. Zaharie, D. Carstea, C.T. Streba, P. Mitrut, A.D. Glodeanu, A.P. Carstea, S.I. Zaharie, I.T. Dascalu, M.J. Tuculina, A. Bunget, M. Bataiosu, N. Ionovici, "Renal Dysfunction - a Possible Marker of Severity of Heart Failure". Revista de Chimie, vol. 69, no. 6, pp. 1435-1440, 2018. [online]. https://doi.org/10.37358/RC.18.6.6341

Text
Mirela Zaharie, Doina Carstea, Costin Teodor Streba, Paul Mitrut, Adina Dorina Glodeanu, Andrei Puiu Carstea, Sorin Ioan Zaharie, Ionela Teodora Dascalu, Mihaela Jana Tuculina, Adina Bunget, Marilena Bataiosu, Nina Ionovici,
Renal Dysfunction - a Possible Marker of Severity of Heart Failure,
Revista de Chimie,
Volume 69, Issue 6,
2018,
Pages 1435-1440,
ISSN 2668-8212,
https://doi.org/10.37358/RC.18.6.6341.
(https://revistadechimie.ro/Articles.asp?ID=6341)
Keywords: renal dysfunction; heart failure; anemia

RIS
TY - JOUR
T1 - Renal Dysfunction - a Possible Marker of Severity of Heart Failure
A1 - Zaharie, Mirela
A2 - Carstea, Doina
A3 - Streba, Costin Teodor
A4 - Mitrut, Paul
A5 - Glodeanu, Adina Dorina
A6 - Carstea, Andrei Puiu
A7 - Zaharie, Sorin Ioan
A8 - Dascalu, Ionela Teodora
A9 - Tuculina, Mihaela Jana
A10 - Bunget, Adina
A11 - Bataiosu, Marilena
A12 - Ionovici, Nina
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2018
VL - 69
IS - 6
SP - 1435
EP - 1440
UR - https://doi.org/10.37358/RC.18.6.6341
KW - renal dysfunction
KW - heart failure
KW - anemia
ER -

BibTex
@article{RevCh2018P1435,
author = {Zaharie Mirela and Carstea Doina and Streba Costin Teodor and Mitrut Paul and Glodeanu Adina Dorina and Carstea Andrei Puiu and Zaharie Sorin Ioan and Dascalu Ionela Teodora and Tuculina Mihaela Jana and Bunget Adina and Bataiosu Marilena and Ionovici Nina},
title = {Renal Dysfunction - a Possible Marker of Severity of Heart Failure},
journal = {Revista de Chimie},
volume = {69},
number = {6},
pages = {1435-1440},
year = {2018},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.18.6.6341},
url = {https://revistadechimie.ro/Articles.asp?ID=6341}
}

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