Study of Dynamics of Immunobiochemical Parameters and Pharmacological Interferences in the Metabolic Syndrome

Rusu, Ana Roxana Ganceanu; Tartau, Liliana Mititelu; Statescu, Cristian; Boanca, Mihaela; Poroch, Vladimir; Lupusoru, Raoul Vasile; Dima, Nicoleta; Badescu, Codruta; Rezus, Elena; Rezus, Ciprian; Lupusoru, Catalina Elena

Ana Roxana Ganceanu Rusu, Liliana Mititelu Tartau, Cristian Statescu, Mihaela Boanca, Vladimir Poroch, Raoul Vasile Lupusoru, Nicoleta Dima, Codruta Badescu, Elena Rezus, Ciprian Rezus, Catalina Elena Lupusoru

Study of Dynamics of Immunobiochemical Parameters and Pharmacological Interferences in the Metabolic Syndrome

Abstract:

The metabolic syndrome (MetS) represents a frequent disorder of the present age, with increased global prevalence, with complex etiopathogenesis and physiopathology, with great impact upon the patients, society and economy and which often is difficult to treat. The main aim of the study was the evaluation of the pharmacodynamic effects of associated angiotensin-converting enzyme (ACE) inhibitors with non-steroidal anti-inflammatory drugs (NSAIDs) on blood pressure values and markers of oxidative stress in rats with MetS. Material and methods: 9 groups of 6 Wistar rats weighing between 150-200g with uniform gender distribution were subjected to cholesterol diet. During 4 weeks, their exercise capacities were analyzed over a 10-minute interval after administration of the test substances. Results: All groups who received cholesterol showed significant increases in serum cortisol. The group receiving Enalapril noted the highest levels of superoxide dismutase (SOD). Conclusions: Comparing the results obtained in this study with the literature, it was noted that the administration of ACE and / or NSAIDs significantly improves the process of chronic inflammation.

Keywords:
metabolic syndrome; immuno-biochemical markers; cortisol; interleukins

Issue: 2018, Volume 69, Issue 6

Pages: 1493-1497

Publication date: 2018/7/15

https://doi.org/10.37358/RC.18.6.6353

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Citation Styles

Cite this article as:
RUSU, A.R.G., TARTAU, L.M., STATESCU, C., BOANCA, M., POROCH, V., LUPUSORU, R.V., DIMA, N., BADESCU, C., REZUS, E., REZUS, C., LUPUSORU, C.E., Study of Dynamics of Immunobiochemical Parameters and Pharmacological Interferences in the Metabolic Syndrome, Rev. Chim., 69(6), 2018, 1493-1497.

Vancouver
Rusu ARG, Tartau LM, Statescu C, Boanca M, Poroch V, Lupusoru RV, Dima N, Badescu C, Rezus E, Rezus C, Lupusoru CE. Study of Dynamics of Immunobiochemical Parameters and Pharmacological Interferences in the Metabolic Syndrome. Rev. Chim.[internet]. 2018 Jun;69(6):1493-1497. Available from: https://doi.org/10.37358/RC.18.6.6353

APA 6th edition
Rusu, A.R.G., Tartau, L.M., Statescu, C., Boanca, M., Poroch, V., Lupusoru, R.V.,... Lupusoru, C.E. (2018). Study of Dynamics of Immunobiochemical Parameters and Pharmacological Interferences in the Metabolic Syndrome. Revista de Chimie, 69(6), 1493-1497. https://doi.org/10.37358/RC.18.6.6353

Harvard
Rusu, A.R.G., Tartau, L.M., Statescu, C., Boanca, M., Poroch, V., Lupusoru, R.V., Dima, N., Badescu, C., Rezus, E., Rezus, C., Lupusoru, C.E. (2018). 'Study of Dynamics of Immunobiochemical Parameters and Pharmacological Interferences in the Metabolic Syndrome', Revista de Chimie, 69(6), pp. 1493-1497. https://doi.org/10.37358/RC.18.6.6353

IEEE
A.R.G. Rusu, L.M. Tartau, C. Statescu, M. Boanca, V. Poroch, R.V. Lupusoru, N. Dima, C. Badescu, E. Rezus, C. Rezus, C.E. Lupusoru, "Study of Dynamics of Immunobiochemical Parameters and Pharmacological Interferences in the Metabolic Syndrome". Revista de Chimie, vol. 69, no. 6, pp. 1493-1497, 2018. [online]. https://doi.org/10.37358/RC.18.6.6353

Text
Ana Roxana Ganceanu Rusu, Liliana Mititelu Tartau, Cristian Statescu, Mihaela Boanca, Vladimir Poroch, Raoul Vasile Lupusoru, Nicoleta Dima, Codruta Badescu, Elena Rezus, Ciprian Rezus, Catalina Elena Lupusoru,
Study of Dynamics of Immunobiochemical Parameters and Pharmacological Interferences in the Metabolic Syndrome,
Revista de Chimie,
Volume 69, Issue 6,
2018,
Pages 1493-1497,
ISSN 2668-8212,
https://doi.org/10.37358/RC.18.6.6353.
(https://revistadechimie.ro/Articles.asp?ID=6353)
Keywords: metabolic syndrome; immuno-biochemical markers; cortisol; interleukins

RIS
TY - JOUR
T1 - Study of Dynamics of Immunobiochemical Parameters and Pharmacological Interferences in the Metabolic Syndrome
A1 - Rusu, Ana Roxana Ganceanu
A2 - Tartau, Liliana Mititelu
A3 - Statescu, Cristian
A4 - Boanca, Mihaela
A5 - Poroch, Vladimir
A6 - Lupusoru, Raoul Vasile
A7 - Dima, Nicoleta
A8 - Badescu, Codruta
A9 - Rezus, Elena
A10 - Rezus, Ciprian
A11 - Lupusoru, Catalina Elena
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2018
VL - 69
IS - 6
SP - 1493
EP - 1497
UR - https://doi.org/10.37358/RC.18.6.6353
KW - metabolic syndrome
KW - immuno-biochemical markers
KW - cortisol
KW - interleukins
ER -

BibTex
@article{RevCh2018P1493,
author = {Rusu Ana Roxana Ganceanu and Tartau Liliana Mititelu and Statescu Cristian and Boanca Mihaela and Poroch Vladimir and Lupusoru Raoul Vasile and Dima Nicoleta and Badescu Codruta and Rezus Elena and Rezus Ciprian and Lupusoru Catalina Elena},
title = {Study of Dynamics of Immunobiochemical Parameters and Pharmacological Interferences in the Metabolic Syndrome},
journal = {Revista de Chimie},
volume = {69},
number = {6},
pages = {1493-1497},
year = {2018},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.18.6.6353},
url = {https://revistadechimie.ro/Articles.asp?ID=6353}
}

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