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REVISTA DE CHIMIE
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https://doi.org/10.37358/Rev.Chim.1949

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Revista de Chimie (Rev. Chim.), Year 2018, Volume 69, Issue 9, 2425-2429

https://doi.org/10.37358/RC.18.9.6546

Carmen Gadau, Elena Ardeleanu, Roxana Folescu, Ioan Tilea, Andreea Varga, Alexandra Simona Zamfir, Mihaela Boanca, Romeo Petru Dobrin, Liliana Strat, Teim Baaj, Patricia Nicola, Alina Costina Luca, Daniela Gurgus

Prevalence, Characteristics and Predictive Factors of Microalbuminuria in Resistant Systemic Arterial Hypertension

Abstract:

The present cross-sectional observational study was made in family medicine offices of Timi’ County, Romania. The aim of the study was to investigate the prevalence of urinary microalbumin excretion (MAU) in resistant systemic arterial hypertension (RH), to analyze patients’ biochemical and clinical characteristics, and the predictive factors for MAU. From a total number of 347 patients, MAU was detected in 76 cases (21.9%). The microalbuminuria positive patients were older, with significant higher office systolic blood pressure (BP) (155 ± 13.50 vs 148 ± 12.40 mmHg, p [ 0.0001) and diastolic blood pressure (94 ± 12.20 vs 88 ± 14.6 mmHg, p = 0.0013), higher prevalence of left ventricular hypertrophy, diabetes mellitus, obesity, ischemic and peripheral arterial disease. MAU positive patients presented statistical significant differences in biochemical data concerning: fasting plasma glucose (FPG) (118.80 ± 32.02 vs 108.01 ± 26.01 mg/dL, p = 0.003), impaired glucose tolerance (IGT) (10.52 % vs 4.94 %), glycated hemoglobin (HbA1c) (6.56 ± 0.98% vs 5.96 ± 0.91%, p [ 0.001), reduced estimated glomerular filtration rate (eGFR) (56.10 ± 15.4 vs 69.30 ± 17.5 ml/min/1.73m2, p [ 0.001) and higher potassium levels (4.71 ± 0.43 vs 4.59 ± 0.44 mg/dL, p = 0.0378). No significant differences were noticed regarding LDL- and HDL-cholesterol, triglycerides, uric acid and serum creatinine. In a logistic multivariate analysis independent predictors for MAU were: systolic BP (odds ratio, OR = 1.024, 95% confidence interval, CI:1.011-1.039, p [ 0.001), HbA1c (OR = 1.324, 95% CI: 1.078-1.724, p = 0.008) and eGFR (OR = 0.989, 95% CI: 0.977-0.999, p = 0.01). Our findings suggest that an important part of RH patients have microalbuminuria and highlight the importance of controlling its predictors, in order to improve patients’ outcome.
Keywords:
microalbuminuria; resistant systemic arterial hypertension-evaluation

Issue: 2018, Volume 69, Issue 9
Pages: 2425-2429
Publication date: 2018/10/15
https://doi.org/10.37358/RC.18.9.6546
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Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
GADAU, C., ARDELEANU, E., FOLESCU, R., TILEA, I., VARGA, A., ZAMFIR, A.S., BOANCA, M., DOBRIN, R.P., STRAT, L., BAAJ, T., NICOLA, P., LUCA, A.C., GURGUS, D., Prevalence, Characteristics and Predictive Factors of Microalbuminuria in Resistant Systemic Arterial Hypertension, Rev. Chim., 69(9), 2018, 2425-2429.

Vancouver
Gadau C, Ardeleanu E, Folescu R, Tilea I, Varga A, Zamfir AS, Boanca M, Dobrin RP, Strat L, Baaj T, Nicola P, Luca AC, Gurgus D. Prevalence, Characteristics and Predictive Factors of Microalbuminuria in Resistant Systemic Arterial Hypertension. Rev. Chim.[internet]. 2018 Sep;69(9):2425-2429. Available from: https://doi.org/10.37358/RC.18.9.6546


APA 6th edition
Gadau, C., Ardeleanu, E., Folescu, R., Tilea, I., Varga, A., Zamfir, A.S.,... Gurgus, D. (2018). Prevalence, Characteristics and Predictive Factors of Microalbuminuria in Resistant Systemic Arterial Hypertension. Revista de Chimie, 69(9), 2425-2429. https://doi.org/10.37358/RC.18.9.6546


Harvard
Gadau, C., Ardeleanu, E., Folescu, R., Tilea, I., Varga, A., Zamfir, A.S., Boanca, M., Dobrin, R.P., Strat, L., Baaj, T., Nicola, P., Luca, A.C., Gurgus, D. (2018). 'Prevalence, Characteristics and Predictive Factors of Microalbuminuria in Resistant Systemic Arterial Hypertension', Revista de Chimie, 69(9), pp. 2425-2429. https://doi.org/10.37358/RC.18.9.6546


IEEE
C. Gadau, E. Ardeleanu, R. Folescu, I. Tilea, A. Varga, A.S. Zamfir, M. Boanca, R.P. Dobrin, L. Strat, T. Baaj, P. Nicola, A.C. Luca, D. Gurgus, "Prevalence, Characteristics and Predictive Factors of Microalbuminuria in Resistant Systemic Arterial Hypertension". Revista de Chimie, vol. 69, no. 9, pp. 2425-2429, 2018. [online]. https://doi.org/10.37358/RC.18.9.6546


Text
Carmen Gadau, Elena Ardeleanu, Roxana Folescu, Ioan Tilea, Andreea Varga, Alexandra Simona Zamfir, Mihaela Boanca, Romeo Petru Dobrin, Liliana Strat, Teim Baaj, Patricia Nicola, Alina Costina Luca, Daniela Gurgus,
Prevalence, Characteristics and Predictive Factors of Microalbuminuria in Resistant Systemic Arterial Hypertension,
Revista de Chimie,
Volume 69, Issue 9,
2018,
Pages 2425-2429,
ISSN 2668-8212,
https://doi.org/10.37358/RC.18.9.6546.
(https://revistadechimie.ro/Articles.asp?ID=6546)
Keywords: microalbuminuria; resistant systemic arterial hypertension-evaluation


RIS
TY - JOUR
T1 - Prevalence, Characteristics and Predictive Factors of Microalbuminuria in Resistant Systemic Arterial Hypertension
A1 - Gadau, Carmen
A2 - Ardeleanu, Elena
A3 - Folescu, Roxana
A4 - Tilea, Ioan
A5 - Varga, Andreea
A6 - Zamfir, Alexandra Simona
A7 - Boanca, Mihaela
A8 - Dobrin, Romeo Petru
A9 - Strat, Liliana
A10 - Baaj, Teim
A11 - Nicola, Patricia
A12 - Luca, Alina Costina
A13 - Gurgus, Daniela
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2018
VL - 69
IS - 9
SP - 2425
EP - 2429
UR - https://doi.org/10.37358/RC.18.9.6546
KW - microalbuminuria
KW - resistant systemic arterial hypertension-evaluation
ER -


BibTex
@article{RevCh2018P2425,
author = {Gadau Carmen and Ardeleanu Elena and Folescu Roxana and Tilea Ioan and Varga Andreea and Zamfir Alexandra Simona and Boanca Mihaela and Dobrin Romeo Petru and Strat Liliana and Baaj Teim and Nicola Patricia and Luca Alina Costina and Gurgus Daniela},
title = {Prevalence, Characteristics and Predictive Factors of Microalbuminuria in Resistant Systemic Arterial Hypertension},
journal = {Revista de Chimie},
volume = {69},
number = {9},
pages = {2425-2429},
year = {2018},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.18.9.6546},
url = {https://revistadechimie.ro/Articles.asp?ID=6546}
}
 
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