ABOUT INDEXING BOARD ARCHIVES AUTHOR GUIDELINES SUBMIT PAPER AUTHOR'S PAGE NEWS, EVENTS CONTACT
REVISTA DE CHIMIE
Cite as: Rev. Chim.
https://doi.org/10.37358/Rev.Chim.1949

OSIM Nr. R102355
ISSN Online 2668-8212
ISSN Print: 1582-9049
ISSN-L: 1582-9049

REVISTA DE CHIMIE Latest Issue

LATEST ISSUE >>>

   Volume 75, 2024
   Volume 74, 2023
   Volume 73, 2022
   Volume 72, 2021
   Volume 71, 2020
   Volume 70, 2019
   Volume 69, 2018
   Volume 68, 2017
   Volume 67, 2016
   Volume 66, 2015
   Volume 65, 2014
   Volume 64, 2013
   Volume 63, 2012
   Volume 62, 2011
   Volume 61, 2010
   Volume 60, 2009
   Volume 59, 2008
   Volume 58, 2007
 
<<<< back

Revista de Chimie (Rev. Chim.), Year 2018, Volume 69, Issue 9, 2472-2475

https://doi.org/10.37358/RC.18.9.6556

Andra Cocolos, Adina Ghemigian, Nicoleta Dumitru, Eugeniya Nedeltcheva Petrova, Mircea Ghemigian, Andra Caragheorgheopol, Dumitru Ioachim, Catalina Poiana

Lower Vitamin D Status in Patients with Differentiated Thyroid Carcinoma

Abstract:

Thyroid cancer (TC) has become the most rapidly increasing type of cancer representing 1-1.5% of all cancers diagnosed annually probably due to intensive screening. It is estimated that the death rate of TC has slowly increased from 0.49 to 0.51/100.000 in the last 10 years and 53.990 new cases will be diagnosed in 2018 in the United States. Therefore, efforts are being made in order to stop the increasing incidence and genetic alterations are thoroughly studied. One of the most recent incriminated factors in TC etiology and physiopathology is vitamin D deficiency. Besides the well-known role in bone metabolism, vitamin D has extra-skeletal effects exerted through the vitamin D receptor (VDR) and has been shown to interfere with many cellular functions such as inhibiting cell proliferation, stimulating differentiation and malignant cell apoptosis in different types of cancer. Cross-sectional, retrospective study which included 114 patients (71 with confirmed thyroid cancer and 43 patients in the control group with benign pathology). Preoperative levels of 25(OH)vitamin D, PTH, biochemical and thyroid panel were measured. The histopathologic features were analyzed. Mean values of vitamin D was 16.31 ± 7.14 ng/mL with lower levels in patients with thyroid cancer (14.95 ± 5.91 ng/mL) in comparison to patients with benign thyroid pathology (18.55 ± 8.41 ng/mL), with a p value of 0.008. Majority of the cases were papillary thyroid cancer (97.18%) in stage 3 (45.07%). Vitamin D levels also correlated negatively with TNM staging. The necessity of further studies is a reality in order to establish if vitamin D deficiency is a possible risk factor for thyroid cancer and its correction can be considered an additional therapy.
Keywords:
thyroid cancer; vitamin D; 25-hydroxyvitamin D

Issue: 2018, Volume 69, Issue 9
Pages: 2472-2475
Publication date: 2018/10/15
https://doi.org/10.37358/RC.18.9.6556
download pdf   Download Pdf Article
Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
COCOLOS, A., GHEMIGIAN, A., DUMITRU, N., PETROVA, E.N., GHEMIGIAN, M., CARAGHEORGHEOPOL, A., IOACHIM, D., POIANA, C., Lower Vitamin D Status in Patients with Differentiated Thyroid Carcinoma, Rev. Chim., 69(9), 2018, 2472-2475.

Vancouver
Cocolos A, Ghemigian A, Dumitru N, Petrova EN, Ghemigian M, Caragheorgheopol A, Ioachim D, Poiana C. Lower Vitamin D Status in Patients with Differentiated Thyroid Carcinoma. Rev. Chim.[internet]. 2018 Sep;69(9):2472-2475. Available from: https://doi.org/10.37358/RC.18.9.6556


APA 6th edition
Cocolos, A., Ghemigian, A., Dumitru, N., Petrova, E.N., Ghemigian, M., Caragheorgheopol, A., Ioachim, D. & Poiana, C. (2018). Lower Vitamin D Status in Patients with Differentiated Thyroid Carcinoma. Revista de Chimie, 69(9), 2472-2475. https://doi.org/10.37358/RC.18.9.6556


Harvard
Cocolos, A., Ghemigian, A., Dumitru, N., Petrova, E.N., Ghemigian, M., Caragheorgheopol, A., Ioachim, D., Poiana, C. (2018). 'Lower Vitamin D Status in Patients with Differentiated Thyroid Carcinoma', Revista de Chimie, 69(9), pp. 2472-2475. https://doi.org/10.37358/RC.18.9.6556


IEEE
A. Cocolos, A. Ghemigian, N. Dumitru, E.N. Petrova, M. Ghemigian, A. Caragheorgheopol, D. Ioachim, C. Poiana, "Lower Vitamin D Status in Patients with Differentiated Thyroid Carcinoma". Revista de Chimie, vol. 69, no. 9, pp. 2472-2475, 2018. [online]. https://doi.org/10.37358/RC.18.9.6556


Text
Andra Cocolos, Adina Ghemigian, Nicoleta Dumitru, Eugeniya Nedeltcheva Petrova, Mircea Ghemigian, Andra Caragheorgheopol, Dumitru Ioachim, Catalina Poiana,
Lower Vitamin D Status in Patients with Differentiated Thyroid Carcinoma,
Revista de Chimie,
Volume 69, Issue 9,
2018,
Pages 2472-2475,
ISSN 2668-8212,
https://doi.org/10.37358/RC.18.9.6556.
(https://revistadechimie.ro/Articles.asp?ID=6556)
Keywords: thyroid cancer; vitamin D; 25-hydroxyvitamin D


RIS
TY - JOUR
T1 - Lower Vitamin D Status in Patients with Differentiated Thyroid Carcinoma
A1 - Cocolos, Andra
A2 - Ghemigian, Adina
A3 - Dumitru, Nicoleta
A4 - Petrova, Eugeniya Nedeltcheva
A5 - Ghemigian, Mircea
A6 - Caragheorgheopol, Andra
A7 - Ioachim, Dumitru
A8 - Poiana, Catalina
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2018
VL - 69
IS - 9
SP - 2472
EP - 2475
UR - https://doi.org/10.37358/RC.18.9.6556
KW - thyroid cancer
KW - vitamin D
KW - 25-hydroxyvitamin D
ER -


BibTex
@article{RevCh2018P2472,
author = {Cocolos Andra and Ghemigian Adina and Dumitru Nicoleta and Petrova Eugeniya Nedeltcheva and Ghemigian Mircea and Caragheorgheopol Andra and Ioachim Dumitru and Poiana Catalina},
title = {Lower Vitamin D Status in Patients with Differentiated Thyroid Carcinoma},
journal = {Revista de Chimie},
volume = {69},
number = {9},
pages = {2472-2475},
year = {2018},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.18.9.6556},
url = {https://revistadechimie.ro/Articles.asp?ID=6556}
}
 
<<<< back
 
PUBLISHING SECTION
Author Guidelines
 * Paper Drafting
 * Paper Template
 * Ethical Statement
 * Paper Submission
Ghidul Autorului (ro)
Submit Paper
Author's Page
Publishing Ethics
Peer Review Process
Open Access & Archiving Policy
 Search Authors
 LATEST NEWS
REvista de Chimie NUMAR OMAGIAL PETRU PONI.. detalii
REvista de Chimie Revista de Chimie - 70 de ani de aparitie neintrerupta.. detalii
dictionar English-Romanian Dictionary for Mechanical Engineering
(download pdf)
  News, Events
Crossref Member Badge
 DOI  logo
 Gold Open Access | Source=http://www.plos.org/  | Author=art designer at PLoS
Creative Commons License
 Conferences of Contemporary
 Chemistry
 Biblioteca Chimiei
 Materiale Plastice