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https://doi.org/10.37358/Rev.Chim.1949

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Revista de Chimie (Rev. Chim.), Year 2018, Volume 69, Issue 10, 2845-2849

https://doi.org/10.37358/RC.18.10.6637

Daniela Gurgus, Elena Ardeleanu, Carmen Gadau, Roxana Folescu, Ioan Tilea, Andreea Varga, Alexandra Simona Zamfir, Mihaela Boanca, Alina Costina Luca, Carmen Lacramioara Zamfir, Teim Baaj, Patricia Nicola

Prevalence, Biochemical and Clinical Characteristics of Resistant Hypertension

Abstract:

The objectives of the present study were to evaluate the prevalence of resistant hypertension (RH) in primary care setting and to analyse its biochemical and clinical characteristics. After 3 months of treatment and evaluation, 721 (14.01%) of 5,146 patients with hypertension did not reach target office blood pressure of [ 140/90 mmHg. After exclusion of „white-coat effect” with ambulatory blood pressure, of secondary and pseudo- resistant hypertension, prevalence of RH was 6.74%. Lifestyle factors associated with RH were physical inactivity, obesity, high salt intake, smoking and excessive alcohol ingestion. Compared to controlled hypertension, RH patients presented higher incidence of family history of cardiovascular disease (38.90% vs 25.94%), diabetes mellitus (34.87% vs 19.01%), impaired fasting glucose (21.91% vs 19.07%), target organ damage (29.1% vs 15.95%), and cardiovascular disease (27.09% vs 17.06%). Dyslipidaemia (52.90% vs 42.03%), fasting plasma glucose (116.10±38.9 vs 107.80±37.2), HbA1c (6.41±1.42 vs 5.96±0.94), serum creatinine (1.09±0.27 vs 1.03±0.24) and microalbuminuria (21.90% vs 10.95%) were significantly higher in RH. Predictors of RH, determined by a multivariate logistic regression analysis were left ventricular hypertrophy (OD 2.14, 95% CI 1.32-3.69), renal impairment expressed as eGFR [ 60 ml/min/1.73m2 (OD 1.62, 95% CI 1.21-2.21) and the presence of cardiovascular disease (OD 1.48, 95% CI 1.02-2.16).
Keywords:
Resistant hypertension; prevalence; laboratory evaluation; predictors; clinical characteristics

Issue: 2018, Volume 69, Issue 10
Pages: 2845-2849
Publication date: 2018/11/15
https://doi.org/10.37358/RC.18.10.6637
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Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
GURGUS, D., ARDELEANU, E., GADAU, C., FOLESCU, R., TILEA, I., VARGA, A., ZAMFIR, A.S., BOANCA, M., LUCA, A.C., ZAMFIR, C.L., BAAJ, T., NICOLA, P., Prevalence, Biochemical and Clinical Characteristics of Resistant Hypertension, Rev. Chim., 69(10), 2018, 2845-2849.

Vancouver
Gurgus D, Ardeleanu E, Gadau C, Folescu R, Tilea I, Varga A, Zamfir AS, Boanca M, Luca AC, Zamfir CL, Baaj T, Nicola P. Prevalence, Biochemical and Clinical Characteristics of Resistant Hypertension. Rev. Chim.[internet]. 2018 Oct;69(10):2845-2849. Available from: https://doi.org/10.37358/RC.18.10.6637


APA 6th edition
Gurgus, D., Ardeleanu, E., Gadau, C., Folescu, R., Tilea, I., Varga, A.,... Nicola, P. (2018). Prevalence, Biochemical and Clinical Characteristics of Resistant Hypertension. Revista de Chimie, 69(10), 2845-2849. https://doi.org/10.37358/RC.18.10.6637


Harvard
Gurgus, D., Ardeleanu, E., Gadau, C., Folescu, R., Tilea, I., Varga, A., Zamfir, A.S., Boanca, M., Luca, A.C., Zamfir, C.L., Baaj, T., Nicola, P. (2018). 'Prevalence, Biochemical and Clinical Characteristics of Resistant Hypertension', Revista de Chimie, 69(10), pp. 2845-2849. https://doi.org/10.37358/RC.18.10.6637


IEEE
D. Gurgus, E. Ardeleanu, C. Gadau, R. Folescu, I. Tilea, A. Varga, A.S. Zamfir, M. Boanca, A.C. Luca, C.L. Zamfir, T. Baaj, P. Nicola, "Prevalence, Biochemical and Clinical Characteristics of Resistant Hypertension". Revista de Chimie, vol. 69, no. 10, pp. 2845-2849, 2018. [online]. https://doi.org/10.37358/RC.18.10.6637


Text
Daniela Gurgus, Elena Ardeleanu, Carmen Gadau, Roxana Folescu, Ioan Tilea, Andreea Varga, Alexandra Simona Zamfir, Mihaela Boanca, Alina Costina Luca, Carmen Lacramioara Zamfir, Teim Baaj, Patricia Nicola,
Prevalence, Biochemical and Clinical Characteristics of Resistant Hypertension,
Revista de Chimie,
Volume 69, Issue 10,
2018,
Pages 2845-2849,
ISSN 2668-8212,
https://doi.org/10.37358/RC.18.10.6637.
(https://revistadechimie.ro/Articles.asp?ID=6637)
Keywords: Resistant hypertension; prevalence; laboratory evaluation; predictors; clinical characteristics


RIS
TY - JOUR
T1 - Prevalence, Biochemical and Clinical Characteristics of Resistant Hypertension
A1 - Gurgus, Daniela
A2 - Ardeleanu, Elena
A3 - Gadau, Carmen
A4 - Folescu, Roxana
A5 - Tilea, Ioan
A6 - Varga, Andreea
A7 - Zamfir, Alexandra Simona
A8 - Boanca, Mihaela
A9 - Luca, Alina Costina
A10 - Zamfir, Carmen Lacramioara
A11 - Baaj, Teim
A12 - Nicola, Patricia
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2018
VL - 69
IS - 10
SP - 2845
EP - 2849
UR - https://doi.org/10.37358/RC.18.10.6637
KW - Resistant hypertension
KW - prevalence
KW - laboratory evaluation
KW - predictors
KW - clinical characteristics
ER -


BibTex
@article{RevCh2018P2845,
author = {Gurgus Daniela and Ardeleanu Elena and Gadau Carmen and Folescu Roxana and Tilea Ioan and Varga Andreea and Zamfir Alexandra Simona and Boanca Mihaela and Luca Alina Costina and Zamfir Carmen Lacramioara and Baaj Teim and Nicola Patricia},
title = {Prevalence, Biochemical and Clinical Characteristics of Resistant Hypertension},
journal = {Revista de Chimie},
volume = {69},
number = {10},
pages = {2845-2849},
year = {2018},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.18.10.6637},
url = {https://revistadechimie.ro/Articles.asp?ID=6637}
}
 
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