Serum Concentration of hsCRP - Possible Marker for Therapy Evaluation in Left Ventricular Dysfunction with Preserved Ejection Fraction

Coculescu, Bogdan Ioan; Dinca, Gabi Valeriu; Manole, Gheorghe; Purcarea, Victor Lorin; Oproiu, Ana Maria; Stocheci, Cristina Mariana

Bogdan Ioan Coculescu, Gabi Valeriu Dinca, Gheorghe Manole, Victor Lorin Purcarea, Ana Maria Oproiu, Cristina Mariana Stocheci

Serum Concentration of hsCRP - Possible Marker for Therapy Evaluation in Left Ventricular Dysfunction with Preserved Ejection Fraction

Abstract:

The study on a subset of 208 patients with diastolic dysfunction with the ejection fraction preserved discusses the possibility of circulating CRP levels to be accepted as a diagnostic marker. In order to carry out a comparative analysis of the significance of hsCRP serum values, the study also included a subgroup labeled as control, consisting of the same number of patients, but diagnosed only with painful chronic ischemic cardiopathy - a stable form of angina pectoris. The conclusion of the study is that the circulating level of hs-CRP can be accepted as a diagnostic marker for both ischemic cardiopathy and diastolic dysfunction with preserved ejection fraction. The result, corroborated with data from other studies that recognize the serum concentration of hs-CRP as a predictor marker in cardiovascular disease, supports its usefulness as a marker for cardiac insufficiency with a history of ischemic cardiopathy, without being a marker for assessing the degree of myocardial contractility deficiency.

Keywords:
biomarker; hs-CRP (high-sensitive CRP); cardiac insufficiency with preserved ejection fraction (CI with preserved EF); chronic ischemic heart disease

Issue: 2018, Volume 69, Issue 10

Pages: 2885-2888

Publication date: 2018/11/15

https://doi.org/10.37358/RC.18.10.6646

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
COCULESCU, B.I., DINCA, G.V., MANOLE, G., PURCAREA, V.L., OPROIU, A.M., STOCHECI, C.M., Serum Concentration of hsCRP - Possible Marker for Therapy Evaluation in Left Ventricular Dysfunction with Preserved Ejection Fraction, Rev. Chim., 69(10), 2018, 2885-2888.

Vancouver
Coculescu BI, Dinca GV, Manole G, Purcarea VL, Oproiu AM, Stocheci CM. Serum Concentration of hsCRP - Possible Marker for Therapy Evaluation in Left Ventricular Dysfunction with Preserved Ejection Fraction. Rev. Chim.[internet]. 2018 Oct;69(10):2885-2888. Available from: https://doi.org/10.37358/RC.18.10.6646

APA 6th edition
Coculescu, B.I., Dinca, G.V., Manole, G., Purcarea, V.L., Oproiu, A.M. & Stocheci, C.M. (2018). Serum Concentration of hsCRP - Possible Marker for Therapy Evaluation in Left Ventricular Dysfunction with Preserved Ejection Fraction. Revista de Chimie, 69(10), 2885-2888. https://doi.org/10.37358/RC.18.10.6646

Harvard
Coculescu, B.I., Dinca, G.V., Manole, G., Purcarea, V.L., Oproiu, A.M., Stocheci, C.M. (2018). 'Serum Concentration of hsCRP - Possible Marker for Therapy Evaluation in Left Ventricular Dysfunction with Preserved Ejection Fraction', Revista de Chimie, 69(10), pp. 2885-2888. https://doi.org/10.37358/RC.18.10.6646

IEEE
B.I. Coculescu, G.V. Dinca, G. Manole, V.L. Purcarea, A.M. Oproiu, C.M. Stocheci, "Serum Concentration of hsCRP - Possible Marker for Therapy Evaluation in Left Ventricular Dysfunction with Preserved Ejection Fraction". Revista de Chimie, vol. 69, no. 10, pp. 2885-2888, 2018. [online]. https://doi.org/10.37358/RC.18.10.6646

Text
Bogdan Ioan Coculescu, Gabi Valeriu Dinca, Gheorghe Manole, Victor Lorin Purcarea, Ana Maria Oproiu, Cristina Mariana Stocheci,
Serum Concentration of hsCRP - Possible Marker for Therapy Evaluation in Left Ventricular Dysfunction with Preserved Ejection Fraction,
Revista de Chimie,
Volume 69, Issue 10,
2018,
Pages 2885-2888,
ISSN 2668-8212,
https://doi.org/10.37358/RC.18.10.6646.
(https://revistadechimie.ro/Articles.asp?ID=6646)
Keywords: biomarker; hs-CRP (high-sensitive CRP); cardiac insufficiency with preserved ejection fraction (CI with preserved EF); chronic ischemic heart disease

RIS
TY - JOUR
T1 - Serum Concentration of hsCRP - Possible Marker for Therapy Evaluation in Left Ventricular Dysfunction with Preserved Ejection Fraction
A1 - Coculescu, Bogdan Ioan
A2 - Dinca, Gabi Valeriu
A3 - Manole, Gheorghe
A4 - Purcarea, Victor Lorin
A5 - Oproiu, Ana Maria
A6 - Stocheci, Cristina Mariana
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2018
VL - 69
IS - 10
SP - 2885
EP - 2888
UR - https://doi.org/10.37358/RC.18.10.6646
KW - biomarker
KW - hs-CRP (high-sensitive CRP)
KW - cardiac insufficiency with preserved ejection fraction (CI with preserved EF)
KW - chronic ischemic heart disease
ER -

BibTex
@article{RevCh2018P2885,
author = {Coculescu Bogdan Ioan and Dinca Gabi Valeriu and Manole Gheorghe and Purcarea Victor Lorin and Oproiu Ana Maria and Stocheci Cristina Mariana},
title = {Serum Concentration of hsCRP - Possible Marker for Therapy Evaluation in Left Ventricular Dysfunction with Preserved Ejection Fraction},
journal = {Revista de Chimie},
volume = {69},
number = {10},
pages = {2885-2888},
year = {2018},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.18.10.6646},
url = {https://revistadechimie.ro/Articles.asp?ID=6646}
}

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