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https://doi.org/10.37358/Rev.Chim.1949

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Revista de Chimie (Rev. Chim.), Year 2018, Volume 69, Issue 10, 2904-2909

https://doi.org/10.37358/RC.18.10.6650

Florin Obadan, Monica Craitoiu, Horia Manolea, Laurentiu Mogoanta, Eugen Osiac, Radu Rica, Alex Ioan Salan, Kamel Earar

Osseointegration Evaluation of Two Socket Preservation Materials in Small Diameter Bone Cavities An in vivo lab rats study

Abstract:

The present study aims to evaluate the osseointegration in small diameter rat bone cavities of a collagen-based material and a synthetic bone graft by using a protocol consisting of three evaluation methods: direct macroscopic examination, optical coherence tomography (OCT) and a histological study. For this study we made three study groups, each of them consisting of twelve laboratory Whistar rats, one for each studied material and one control group. For each study group, six laboratory rats were sacrificed after two months, and the other six after four months in order to evaluate the bone wound healing.The total amount of augmentation was significantly greater in the augmented groups than in the control group. Macroscopic examination of the evolution of augmented bone wound healing with the collagen-based material offered spectacular results especially in the cavities prepared in the calvaria, while in the bone wounds augmented with OssceramNano we always noticed the presence of synthetic material residual particles. The OCT evaluation highlighted the degree of filling of the defect through the lack of refractivity of the collagen-based material, while the higher refractive index of the synthetic bone graft material allowed some spectacular observations. On the histological samples from the first study group, filled with the collagen-based material, we generally have observed the filling of the experimental bone defects with repairing connective tissue with various bone extensions from the surrounding bone tissue The histological assessment of the synthetic bone graft augmented cavities showed firstly the presence of synthetic material residual particles surrounded by a newly formed connective tissue in early stages or a young bone tissue with many osteoblasts in the advanced stages of osseointegration.
Keywords:
bone augmentation; collagen; synthetic bone graft; optical coherence tomography; histology

Issue: 2018, Volume 69, Issue 10
Pages: 2904-2909
Publication date: 2018/11/15
https://doi.org/10.37358/RC.18.10.6650
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This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
OBADAN, F., CRAITOIU, M., MANOLEA, H., MOGOANTA, L., OSIAC, E., RICA, R., SALAN, A.I., EARAR, K., Osseointegration Evaluation of Two Socket Preservation Materials in Small Diameter Bone Cavities An in vivo lab rats study, Rev. Chim., 69(10), 2018, 2904-2909.

Vancouver
Obadan F, Craitoiu M, Manolea H, Mogoanta L, Osiac E, Rica R, Salan AI, Earar K. Osseointegration Evaluation of Two Socket Preservation Materials in Small Diameter Bone Cavities An in vivo lab rats study. Rev. Chim.[internet]. 2018 Oct;69(10):2904-2909. Available from: https://doi.org/10.37358/RC.18.10.6650


APA 6th edition
Obadan, F., Craitoiu, M., Manolea, H., Mogoanta, L., Osiac, E., Rica, R., Salan, A.I. & Earar, K. (2018). Osseointegration Evaluation of Two Socket Preservation Materials in Small Diameter Bone Cavities An in vivo lab rats study. Revista de Chimie, 69(10), 2904-2909. https://doi.org/10.37358/RC.18.10.6650


Harvard
Obadan, F., Craitoiu, M., Manolea, H., Mogoanta, L., Osiac, E., Rica, R., Salan, A.I., Earar, K. (2018). 'Osseointegration Evaluation of Two Socket Preservation Materials in Small Diameter Bone Cavities An in vivo lab rats study', Revista de Chimie, 69(10), pp. 2904-2909. https://doi.org/10.37358/RC.18.10.6650


IEEE
F. Obadan, M. Craitoiu, H. Manolea, L. Mogoanta, E. Osiac, R. Rica, A.I. Salan, K. Earar, "Osseointegration Evaluation of Two Socket Preservation Materials in Small Diameter Bone Cavities An in vivo lab rats study". Revista de Chimie, vol. 69, no. 10, pp. 2904-2909, 2018. [online]. https://doi.org/10.37358/RC.18.10.6650


Text
Florin Obadan, Monica Craitoiu, Horia Manolea, Laurentiu Mogoanta, Eugen Osiac, Radu Rica, Alex Ioan Salan, Kamel Earar,
Osseointegration Evaluation of Two Socket Preservation Materials in Small Diameter Bone Cavities An in vivo lab rats study,
Revista de Chimie,
Volume 69, Issue 10,
2018,
Pages 2904-2909,
ISSN 2668-8212,
https://doi.org/10.37358/RC.18.10.6650.
(https://revistadechimie.ro/Articles.asp?ID=6650)
Keywords: bone augmentation; collagen; synthetic bone graft; optical coherence tomography; histology


RIS
TY - JOUR
T1 - Osseointegration Evaluation of Two Socket Preservation Materials in Small Diameter Bone Cavities An in vivo lab rats study
A1 - Obadan, Florin
A2 - Craitoiu, Monica
A3 - Manolea, Horia
A4 - Mogoanta, Laurentiu
A5 - Osiac, Eugen
A6 - Rica, Radu
A7 - Salan, Alex Ioan
A8 - Earar, Kamel
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2018
VL - 69
IS - 10
SP - 2904
EP - 2909
UR - https://doi.org/10.37358/RC.18.10.6650
KW - bone augmentation
KW - collagen
KW - synthetic bone graft
KW - optical coherence tomography
KW - histology
ER -


BibTex
@article{RevCh2018P2904,
author = {Obadan Florin and Craitoiu Monica and Manolea Horia and Mogoanta Laurentiu and Osiac Eugen and Rica Radu and Salan Alex Ioan and Earar Kamel},
title = {Osseointegration Evaluation of Two Socket Preservation Materials in Small Diameter Bone Cavities An in vivo lab rats study},
journal = {Revista de Chimie},
volume = {69},
number = {10},
pages = {2904-2909},
year = {2018},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.18.10.6650},
url = {https://revistadechimie.ro/Articles.asp?ID=6650}
}
 
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