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https://doi.org/10.37358/Rev.Chim.1949

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Revista de Chimie (Rev. Chim.), Year 2018, Volume 69, Issue 12, 3341-3344

https://doi.org/10.37358/RC.18.12.6745

Laura Ileana Socea, Stefania Felicia Barbuceanu, Lucian Iscrulescu, Bogdan Socea, Madalina Hrubaru, Elena Mihaela Pahontu, Camelia Cristina Diaconu, Ovidiu Gabriel Bratu, Octavian Tudorel Olaru

New N-acylhydrazones with Potential Cytotoxic Activity

Abstract:

Some new N-acylhydrazones 7a-c having dibenzo[a,d][7]annulene moiety were synthesized by condensation of corresponding hydrazide 5 with aromatic aldehydes. The structures of these newly compounds were elucidated by IR, 1H-NMR, 13C-NMR, and elemental analysis. In the view of the therapeutical potential of the newly compounds, we evaluated their toxicological profile using Daphnia magna bioassay.
Keywords:
acylhydrazone; 5H-dibenzo<7>annulene; cytotoxicity; Daphnia magna bioassays

Issue: 2018, Volume 69, Issue 12
Pages: 3341-3344
Publication date: 2019/1/15
https://doi.org/10.37358/RC.18.12.6745
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Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
SOCEA, L.I., BARBUCEANU, S.F., ISCRULESCU, L., SOCEA, B., HRUBARU, M., PAHONTU, E.M., DIACONU, C.C., BRATU, O.G., OLARU, O.T., New N-acylhydrazones with Potential Cytotoxic Activity, Rev. Chim., 69(12), 2018, 3341-3344.

Vancouver
Socea LI, Barbuceanu SF, Iscrulescu L, Socea B, Hrubaru M, Pahontu EM, Diaconu CC, Bratu OG, Olaru OT. New N-acylhydrazones with Potential Cytotoxic Activity. Rev. Chim.[internet]. 2018 Dec;69(12):3341-3344. Available from: https://doi.org/10.37358/RC.18.12.6745


APA 6th edition
Socea, L.I., Barbuceanu, S.F., Iscrulescu, L., Socea, B., Hrubaru, M., Pahontu, E.M.,... Olaru, O.T. (2018). New N-acylhydrazones with Potential Cytotoxic Activity. Revista de Chimie, 69(12), 3341-3344. https://doi.org/10.37358/RC.18.12.6745


Harvard
Socea, L.I., Barbuceanu, S.F., Iscrulescu, L., Socea, B., Hrubaru, M., Pahontu, E.M., Diaconu, C.C., Bratu, O.G., Olaru, O.T. (2018). 'New N-acylhydrazones with Potential Cytotoxic Activity', Revista de Chimie, 69(12), pp. 3341-3344. https://doi.org/10.37358/RC.18.12.6745


IEEE
L.I. Socea, S.F. Barbuceanu, L. Iscrulescu, B. Socea, M. Hrubaru, E.M. Pahontu, C.C. Diaconu, O.G. Bratu, O.T. Olaru, "New N-acylhydrazones with Potential Cytotoxic Activity". Revista de Chimie, vol. 69, no. 12, pp. 3341-3344, 2018. [online]. https://doi.org/10.37358/RC.18.12.6745


Text
Laura Ileana Socea, Stefania Felicia Barbuceanu, Lucian Iscrulescu, Bogdan Socea, Madalina Hrubaru, Elena Mihaela Pahontu, Camelia Cristina Diaconu, Ovidiu Gabriel Bratu, Octavian Tudorel Olaru,
New N-acylhydrazones with Potential Cytotoxic Activity,
Revista de Chimie,
Volume 69, Issue 12,
2018,
Pages 3341-3344,
ISSN 2668-8212,
https://doi.org/10.37358/RC.18.12.6745.
(https://revistadechimie.ro/Articles.asp?ID=6745)
Keywords: acylhydrazone; 5H-dibenzo<7>annulene; cytotoxicity; Daphnia magna bioassays


RIS
TY - JOUR
T1 - New N-acylhydrazones with Potential Cytotoxic Activity
A1 - Socea, Laura Ileana
A2 - Barbuceanu, Stefania Felicia
A3 - Iscrulescu, Lucian
A4 - Socea, Bogdan
A5 - Hrubaru, Madalina
A6 - Pahontu, Elena Mihaela
A7 - Diaconu, Camelia Cristina
A8 - Bratu, Ovidiu Gabriel
A9 - Olaru, Octavian Tudorel
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2018
VL - 69
IS - 12
SP - 3341
EP - 3344
UR - https://doi.org/10.37358/RC.18.12.6745
KW - acylhydrazone
KW - 5H-dibenzoKW - d><7>annulene
KW - cytotoxicity
KW - Daphnia magna bioassays
ER -


BibTex
@article{RevCh2018P3341,
author = {Socea Laura Ileana and Barbuceanu Stefania Felicia and Iscrulescu Lucian and Socea Bogdan and Hrubaru Madalina and Pahontu Elena Mihaela and Diaconu Camelia Cristina and Bratu Ovidiu Gabriel and Olaru Octavian Tudorel},
title = {New N-acylhydrazones with Potential Cytotoxic Activity},
journal = {Revista de Chimie},
volume = {69},
number = {12},
pages = {3341-3344},
year = {2018},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.18.12.6745},
url = {https://revistadechimie.ro/Articles.asp?ID=6745}
}
 
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