Effects of Acute Organophosphate Poisoning on Glycemic Profile in Weanling Rats An experimental study

Tomescu, Dana; Cobilinschi, Cristian; Baetu, Alexandru; Totan, Alexandra; Neagu, Paul Tiberiu; Diaconu, Camelia Cristina; Tincu, Iulia Florentina; Stoian, Anca Pantea; Bratu, Ovidiu Gabriel; Macovei, Radu Alexandru

Dana Tomescu, Cristian Cobilinschi, Alexandru Baetu, Alexandra Totan, Paul Tiberiu Neagu, Camelia Cristina Diaconu, Iulia Florentina Tincu, Anca Pantea Stoian, Ovidiu Gabriel Bratu, Radu Alexandru Macovei

Effects of Acute Organophosphate Poisoning on Glycemic Profile in Weanling Rats An experimental study

Abstract:

Organophosphates (OP) are frequently used worldwide as pesticides in both agriculture and human households leaving toxic residues in food or living environment. OP act through acetylcholinesterase (AChE) inhibition and acute poisoning carries a higher risk of mortality due to parasympathetic overstimulation. Long-term exposure leads to nervous, hepatic or renal dysfunction. Chlorpyrifos, one of the most commonly used compound appears to cause hyperglycemia, insulin resistance and the risk of developing diabetes after prolonged exposure. The aim of this article was to assess the impact of acute OP poisoning on glycemic status in weanling mice.

Keywords:
organophosphate; chlorpyrifos; cholinesterase inhibition; hyperglycemia; diabetes

Issue: 2018, Volume 69, Issue 12

Pages: 3469-3472

Publication date: 2019/1/15

https://doi.org/10.37358/RC.18.12.6771

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
TOMESCU, D., COBILINSCHI, C., BAETU, A., TOTAN, A., NEAGU, P.T., DIACONU, C.C., TINCU, I.F., STOIAN, A.P., BRATU, O.G., MACOVEI, R.A., Effects of Acute Organophosphate Poisoning on Glycemic Profile in Weanling Rats An experimental study, Rev. Chim., 69(12), 2018, 3469-3472.

Vancouver
Tomescu D, Cobilinschi C, Baetu A, Totan A, Neagu PT, Diaconu CC, Tincu IF, Stoian AP, Bratu OG, Macovei RA. Effects of Acute Organophosphate Poisoning on Glycemic Profile in Weanling Rats An experimental study. Rev. Chim.[internet]. 2018 Dec;69(12):3469-3472. Available from: https://doi.org/10.37358/RC.18.12.6771

APA 6th edition
Tomescu, D., Cobilinschi, C., Baetu, A., Totan, A., Neagu, P.T., Diaconu, C.C.,... Macovei, R.A. (2018). Effects of Acute Organophosphate Poisoning on Glycemic Profile in Weanling Rats An experimental study. Revista de Chimie, 69(12), 3469-3472. https://doi.org/10.37358/RC.18.12.6771

Harvard
Tomescu, D., Cobilinschi, C., Baetu, A., Totan, A., Neagu, P.T., Diaconu, C.C., Tincu, I.F., Stoian, A.P., Bratu, O.G., Macovei, R.A. (2018). 'Effects of Acute Organophosphate Poisoning on Glycemic Profile in Weanling Rats An experimental study', Revista de Chimie, 69(12), pp. 3469-3472. https://doi.org/10.37358/RC.18.12.6771

IEEE
D. Tomescu, C. Cobilinschi, A. Baetu, A. Totan, P.T. Neagu, C.C. Diaconu, I.F. Tincu, A.P. Stoian, O.G. Bratu, R.A. Macovei, "Effects of Acute Organophosphate Poisoning on Glycemic Profile in Weanling Rats An experimental study". Revista de Chimie, vol. 69, no. 12, pp. 3469-3472, 2018. [online]. https://doi.org/10.37358/RC.18.12.6771

Text
Dana Tomescu, Cristian Cobilinschi, Alexandru Baetu, Alexandra Totan, Paul Tiberiu Neagu, Camelia Cristina Diaconu, Iulia Florentina Tincu, Anca Pantea Stoian, Ovidiu Gabriel Bratu, Radu Alexandru Macovei,
Effects of Acute Organophosphate Poisoning on Glycemic Profile in Weanling Rats An experimental study,
Revista de Chimie,
Volume 69, Issue 12,
2018,
Pages 3469-3472,
ISSN 2668-8212,
https://doi.org/10.37358/RC.18.12.6771.
(https://revistadechimie.ro/Articles.asp?ID=6771)
Keywords: organophosphate; chlorpyrifos; cholinesterase inhibition; hyperglycemia; diabetes

RIS
TY - JOUR
T1 - Effects of Acute Organophosphate Poisoning on Glycemic Profile in Weanling Rats An experimental study
A1 - Tomescu, Dana
A2 - Cobilinschi, Cristian
A3 - Baetu, Alexandru
A4 - Totan, Alexandra
A5 - Neagu, Paul Tiberiu
A6 - Diaconu, Camelia Cristina
A7 - Tincu, Iulia Florentina
A8 - Stoian, Anca Pantea
A9 - Bratu, Ovidiu Gabriel
A10 - Macovei, Radu Alexandru
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2018
VL - 69
IS - 12
SP - 3469
EP - 3472
UR - https://doi.org/10.37358/RC.18.12.6771
KW - organophosphate
KW - chlorpyrifos
KW - cholinesterase inhibition
KW - hyperglycemia
KW - diabetes
ER -

BibTex
@article{RevCh2018P3469,
author = {Tomescu Dana and Cobilinschi Cristian and Baetu Alexandru and Totan Alexandra and Neagu Paul Tiberiu and Diaconu Camelia Cristina and Tincu Iulia Florentina and Stoian Anca Pantea and Bratu Ovidiu Gabriel and Macovei Radu Alexandru},
title = {Effects of Acute Organophosphate Poisoning on Glycemic Profile in Weanling Rats An experimental study},
journal = {Revista de Chimie},
volume = {69},
number = {12},
pages = {3469-3472},
year = {2018},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.18.12.6771},
url = {https://revistadechimie.ro/Articles.asp?ID=6771}
}

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