Effect of Ceratonia siliqua Methanolic Extract and 6-hydroxydopamine on Memory Impairment and Oxidative Stress in Zebrafish (Danio rerio) Model

Dumitru, Gabriela; Abidar, Sara; Nhiri, Mohamad; Hritcu, Lucian; Boiangiu, Razvan Stefan; Sandu, Ion; Todirascu-Ciornea, Elena

Gabriela Dumitru, Sara Abidar, Mohamad Nhiri, Lucian Hritcu, Razvan Stefan Boiangiu, Ion Sandu, Elena Todirascu-Ciornea

Effect of Ceratonia siliqua Methanolic Extract and 6-hydroxydopamine on Memory Impairment and Oxidative Stress in Zebrafish (Danio rerio) Model

Abstract:

The richness in soluble sugars and polyphenols, especially condensed tannins, vitamins, minerals and other phytochemicals, recommends Ceratonia siliqua L. species for use in therapeutic practice, especially in terms of neurotoxicity - a major public health problem. Neurodegenerative disorders arise from various metabolic dysfunctions or from the administration of chemicals such as 6-hydroxydopamine (6-OHDA), a catecholaminergic neurotoxin that induces oxidative stress and, implicitly, cellular apoptosis. The results obtained after the administration of the methanolic extract of carob in Danio rerio highlights a phenomenon of prevention of short-term memory deficits, as well as a significant antioxidant activity.

Keywords:
6-OHDA; carob; Danio rerio; memory; oxidative stress

Issue: 2018, Volume 69, Issue 12

Pages: 3545-3548

Publication date: 2019/1/15

https://doi.org/10.37358/RC.18.12.6788

Download Pdf Article

This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
DUMITRU, G., ABIDAR, S., NHIRI, M., HRITCU, L., BOIANGIU, R.S., SANDU, I., TODIRASCU-CIORNEA, E., Effect of Ceratonia siliqua Methanolic Extract and 6-hydroxydopamine on Memory Impairment and Oxidative Stress in Zebrafish (Danio rerio) Model, Rev. Chim., 69(12), 2018, 3545-3548.

Vancouver
Dumitru G, Abidar S, Nhiri M, Hritcu L, Boiangiu RS, Sandu I, Todirascu-Ciornea E. Effect of Ceratonia siliqua Methanolic Extract and 6-hydroxydopamine on Memory Impairment and Oxidative Stress in Zebrafish (Danio rerio) Model. Rev. Chim.[internet]. 2018 Dec;69(12):3545-3548. Available from: https://doi.org/10.37358/RC.18.12.6788

APA 6th edition
Dumitru, G., Abidar, S., Nhiri, M., Hritcu, L., Boiangiu, R.S., Sandu, I. & Todirascu-Ciornea, E. (2018). Effect of Ceratonia siliqua Methanolic Extract and 6-hydroxydopamine on Memory Impairment and Oxidative Stress in Zebrafish (Danio rerio) Model. Revista de Chimie, 69(12), 3545-3548. https://doi.org/10.37358/RC.18.12.6788

Harvard
Dumitru, G., Abidar, S., Nhiri, M., Hritcu, L., Boiangiu, R.S., Sandu, I., Todirascu-Ciornea, E. (2018). 'Effect of Ceratonia siliqua Methanolic Extract and 6-hydroxydopamine on Memory Impairment and Oxidative Stress in Zebrafish (Danio rerio) Model', Revista de Chimie, 69(12), pp. 3545-3548. https://doi.org/10.37358/RC.18.12.6788

IEEE
G. Dumitru, S. Abidar, M. Nhiri, L. Hritcu, R.S. Boiangiu, I. Sandu, E. Todirascu-Ciornea, "Effect of Ceratonia siliqua Methanolic Extract and 6-hydroxydopamine on Memory Impairment and Oxidative Stress in Zebrafish (Danio rerio) Model". Revista de Chimie, vol. 69, no. 12, pp. 3545-3548, 2018. [online]. https://doi.org/10.37358/RC.18.12.6788

Text
Gabriela Dumitru, Sara Abidar, Mohamad Nhiri, Lucian Hritcu, Razvan Stefan Boiangiu, Ion Sandu, Elena Todirascu-Ciornea,
Effect of Ceratonia siliqua Methanolic Extract and 6-hydroxydopamine on Memory Impairment and Oxidative Stress in Zebrafish (Danio rerio) Model,
Revista de Chimie,
Volume 69, Issue 12,
2018,
Pages 3545-3548,
ISSN 2668-8212,
https://doi.org/10.37358/RC.18.12.6788.
(https://revistadechimie.ro/Articles.asp?ID=6788)
Keywords: 6-OHDA; carob; Danio rerio; memory; oxidative stress

RIS
TY - JOUR
T1 - Effect of Ceratonia siliqua Methanolic Extract and 6-hydroxydopamine on Memory Impairment and Oxidative Stress in Zebrafish (Danio rerio) Model
A1 - Dumitru, Gabriela
A2 - Abidar, Sara
A3 - Nhiri, Mohamad
A4 - Hritcu, Lucian
A5 - Boiangiu, Razvan Stefan
A6 - Sandu, Ion
A7 - Todirascu-Ciornea, Elena
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2018
VL - 69
IS - 12
SP - 3545
EP - 3548
UR - https://doi.org/10.37358/RC.18.12.6788
KW - 6-OHDA
KW - carob
KW - Danio rerio
KW - memory
KW - oxidative stress
ER -

BibTex
@article{RevCh2018P3545,
author = {Dumitru Gabriela and Abidar Sara and Nhiri Mohamad and Hritcu Lucian and Boiangiu Razvan Stefan and Sandu Ion and Todirascu-Ciornea Elena},
title = {Effect of Ceratonia siliqua Methanolic Extract and 6-hydroxydopamine on Memory Impairment and Oxidative Stress in Zebrafish (Danio rerio) Model},
journal = {Revista de Chimie},
volume = {69},
number = {12},
pages = {3545-3548},
year = {2018},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.18.12.6788},
url = {https://revistadechimie.ro/Articles.asp?ID=6788}
}

<<<< back

PUBLISHING SECTION

Author Guidelines

* Paper Drafting

* Paper Template

* Ethical Statement

* Paper Submission

Ghidul Autorului (ro)

Open Access & Archiving Policy

Search Authors

LATEST NEWS
	NUMAR OMAGIAL PETRU PONI.. detalii
	Revista de Chimie - 70 de ani de aparitie neintrerupta.. detalii
	English-Romanian Dictionary for Mechanical Engineering (download pdf)