A Pilot Study for Testing the Efficiency of a Novel Integrated On-line Platform Using Tumoral Biomarkers Evaluation in Colorectal Cancer

Isaic, Alexandru; Cheveresan, Adelina; Dobrescu, Amadeus; Tarta, Cristi; Stoica, Laurian; Duta, Ciprian; Fulger, Lazar

Alexandru Isaic, Adelina Cheveresan, Amadeus Dobrescu, Cristi Tarta, Laurian Stoica, Ciprian Duta, Lazar Fulger

A Pilot Study for Testing the Efficiency of a Novel Integrated On-line Platform Using Tumoral Biomarkers Evaluation in Colorectal Cancer

Abstract:

Colorectal cancer (CRC) is one of the leading causes of death among cancer patients in Romania. It is known as a heterogeneous disease, characterized by diversion in multiple molecular pathways during its evolutionary process. This research was focusing on the two biomarkers that are related to CRC, specifically Carcinoembryonic Antigen (CEA) and Carbohydrate Antigen 19-9 (CA 19-9). Being an integral part of a wider study, we explored the use of a novel platform to support the strictly controlled process of data collection on colorectal cancer cases. We collected data about the patients regarding baseline clinical parameters, medical history, important comorbidities, intraoperative findings and adverse events, tumor characteristics, histological findings and main laboratory data (blood cell count, serum protein electrophoresis, liver and kidney function tests, serum levels of CEA and CA19-9). The results suggest that these two biomarkers are useful preoperative indicators of local recurrences and prognosis in colorectal cancer. Increased levels of both tumor markers are correlated with an advanced stage of the disease and a poor prognosis. Finally, this study aims to provide the necessary infrastructure, geared towards efficient, safe and comprehensive clinical evaluation of CRC cases.

Keywords:
colorectal cancer; pilot study; on-line platform; biomarkers

Issue: 2018, Volume 69, Issue 12

Pages: 3557-3560

Publication date: 2019/1/15

https://doi.org/10.37358/RC.18.12.6791

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
ISAIC, A., CHEVERESAN, A., DOBRESCU, A., TARTA, C., STOICA, L., DUTA, C., FULGER, L., A Pilot Study for Testing the Efficiency of a Novel Integrated On-line Platform Using Tumoral Biomarkers Evaluation in Colorectal Cancer, Rev. Chim., 69(12), 2018, 3557-3560.

Vancouver
Isaic A, Cheveresan A, Dobrescu A, Tarta C, Stoica L, Duta C, Fulger L. A Pilot Study for Testing the Efficiency of a Novel Integrated On-line Platform Using Tumoral Biomarkers Evaluation in Colorectal Cancer. Rev. Chim.[internet]. 2018 Dec;69(12):3557-3560. Available from: https://doi.org/10.37358/RC.18.12.6791

APA 6th edition
Isaic, A., Cheveresan, A., Dobrescu, A., Tarta, C., Stoica, L., Duta, C. & Fulger, L. (2018). A Pilot Study for Testing the Efficiency of a Novel Integrated On-line Platform Using Tumoral Biomarkers Evaluation in Colorectal Cancer. Revista de Chimie, 69(12), 3557-3560. https://doi.org/10.37358/RC.18.12.6791

Harvard
Isaic, A., Cheveresan, A., Dobrescu, A., Tarta, C., Stoica, L., Duta, C., Fulger, L. (2018). 'A Pilot Study for Testing the Efficiency of a Novel Integrated On-line Platform Using Tumoral Biomarkers Evaluation in Colorectal Cancer', Revista de Chimie, 69(12), pp. 3557-3560. https://doi.org/10.37358/RC.18.12.6791

IEEE
A. Isaic, A. Cheveresan, A. Dobrescu, C. Tarta, L. Stoica, C. Duta, L. Fulger, "A Pilot Study for Testing the Efficiency of a Novel Integrated On-line Platform Using Tumoral Biomarkers Evaluation in Colorectal Cancer". Revista de Chimie, vol. 69, no. 12, pp. 3557-3560, 2018. [online]. https://doi.org/10.37358/RC.18.12.6791

Text
Alexandru Isaic, Adelina Cheveresan, Amadeus Dobrescu, Cristi Tarta, Laurian Stoica, Ciprian Duta, Lazar Fulger,
A Pilot Study for Testing the Efficiency of a Novel Integrated On-line Platform Using Tumoral Biomarkers Evaluation in Colorectal Cancer,
Revista de Chimie,
Volume 69, Issue 12,
2018,
Pages 3557-3560,
ISSN 2668-8212,
https://doi.org/10.37358/RC.18.12.6791.
(https://revistadechimie.ro/Articles.asp?ID=6791)
Keywords: colorectal cancer; pilot study; on-line platform; biomarkers

RIS
TY - JOUR
T1 - A Pilot Study for Testing the Efficiency of a Novel Integrated On-line Platform Using Tumoral Biomarkers Evaluation in Colorectal Cancer
A1 - Isaic, Alexandru
A2 - Cheveresan, Adelina
A3 - Dobrescu, Amadeus
A4 - Tarta, Cristi
A5 - Stoica, Laurian
A6 - Duta, Ciprian
A7 - Fulger, Lazar
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2018
VL - 69
IS - 12
SP - 3557
EP - 3560
UR - https://doi.org/10.37358/RC.18.12.6791
KW - colorectal cancer
KW - pilot study
KW - on-line platform
KW - biomarkers
ER -

BibTex
@article{RevCh2018P3557,
author = {Isaic Alexandru and Cheveresan Adelina and Dobrescu Amadeus and Tarta Cristi and Stoica Laurian and Duta Ciprian and Fulger Lazar},
title = {A Pilot Study for Testing the Efficiency of a Novel Integrated On-line Platform Using Tumoral Biomarkers Evaluation in Colorectal Cancer},
journal = {Revista de Chimie},
volume = {69},
number = {12},
pages = {3557-3560},
year = {2018},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.18.12.6791},
url = {https://revistadechimie.ro/Articles.asp?ID=6791}
}

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