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https://doi.org/10.37358/Rev.Chim.1949

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Revista de Chimie (Rev. Chim.), Year 2019, Volume 70, Issue 2, 718-720

https://doi.org/10.37358/RC.19.2.6992

Lucia Corina Dima-Cozma, Sebastian Cozma, Delia Hinganu, Cristina Mihaela Ghiciuc, Florin Mitu

Targeting Matrix Metalloproteinases in Atherosclerosis and Cardiovascular Dysfunction

Abstract:

Matrix metalloproteinases (MMPs) are the primary mediators of extracellular remodeling and their properties are useful in diagnostic evaluation and treatment. They are zinc-dependent proteases. MMPs have been involved in the mechanisms of atherosclerosis in various arterial areas, ischemic heart disease and myocardial infarction, atrial fibrillation and aortic aneurysms. Recently, MMP9 has been implicated in dyslipidemia and cholesterol synthesis by the liver. Increased MMP expression and activity has been associated with neointimal arterial lesions and migration of smooth muscle cells after arterial balloon dilation, while MMP inhibition decreases smooth muscle cell migration in vivo and in vitro.
Keywords:
matrix metalloproteinases; atherosclerosis; ischemic heart disease

Issue: 2019, Volume 70, Issue 2
Pages: 718-720
Publication date: 2019/3/15
https://doi.org/10.37358/RC.19.2.6992
download pdf   Download Pdf Article
Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
DIMA-COZMA, L.C., COZMA, S., HINGANU, D., GHICIUC, C.M., MITU, F., Targeting Matrix Metalloproteinases in Atherosclerosis and Cardiovascular Dysfunction, Rev. Chim., 70(2), 2019, 718-720.

Vancouver
Dima-Cozma LC, Cozma S, Hinganu D, Ghiciuc CM, Mitu F. Targeting Matrix Metalloproteinases in Atherosclerosis and Cardiovascular Dysfunction. Rev. Chim.[internet]. 2019 Feb;70(2):718-720. Available from: https://doi.org/10.37358/RC.19.2.6992


APA 6th edition
Dima-Cozma, L.C., Cozma, S., Hinganu, D., Ghiciuc, C.M. & Mitu, F. (2019). Targeting Matrix Metalloproteinases in Atherosclerosis and Cardiovascular Dysfunction. Revista de Chimie, 70(2), 718-720. https://doi.org/10.37358/RC.19.2.6992


Harvard
Dima-Cozma, L.C., Cozma, S., Hinganu, D., Ghiciuc, C.M., Mitu, F. (2019). 'Targeting Matrix Metalloproteinases in Atherosclerosis and Cardiovascular Dysfunction', Revista de Chimie, 70(2), pp. 718-720. https://doi.org/10.37358/RC.19.2.6992


IEEE
L.C. Dima-Cozma, S. Cozma, D. Hinganu, C.M. Ghiciuc, F. Mitu, "Targeting Matrix Metalloproteinases in Atherosclerosis and Cardiovascular Dysfunction". Revista de Chimie, vol. 70, no. 2, pp. 718-720, 2019. [online]. https://doi.org/10.37358/RC.19.2.6992


Text
Lucia Corina Dima-Cozma, Sebastian Cozma, Delia Hinganu, Cristina Mihaela Ghiciuc, Florin Mitu,
Targeting Matrix Metalloproteinases in Atherosclerosis and Cardiovascular Dysfunction,
Revista de Chimie,
Volume 70, Issue 2,
2019,
Pages 718-720,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.2.6992.
(https://revistadechimie.ro/Articles.asp?ID=6992)
Keywords: matrix metalloproteinases; atherosclerosis; ischemic heart disease


RIS
TY - JOUR
T1 - Targeting Matrix Metalloproteinases in Atherosclerosis and Cardiovascular Dysfunction
A1 - Dima-Cozma, Lucia Corina
A2 - Cozma, Sebastian
A3 - Hinganu, Delia
A4 - Ghiciuc, Cristina Mihaela
A5 - Mitu, Florin
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 2
SP - 718
EP - 720
UR - https://doi.org/10.37358/RC.19.2.6992
KW - matrix metalloproteinases
KW - atherosclerosis
KW - ischemic heart disease
ER -


BibTex
@article{RevCh2019P718,
author = {Dima-Cozma Lucia Corina and Cozma Sebastian and Hinganu Delia and Ghiciuc Cristina Mihaela and Mitu Florin},
title = {Targeting Matrix Metalloproteinases in Atherosclerosis and Cardiovascular Dysfunction},
journal = {Revista de Chimie},
volume = {70},
number = {2},
pages = {718-720},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.2.6992},
url = {https://revistadechimie.ro/Articles.asp?ID=6992}
}
 
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