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https://doi.org/10.37358/Rev.Chim.1949

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Revista de Chimie (Rev. Chim.), Year 2019, Volume 70, Issue 3, 1089-1093

https://doi.org/10.37358/RC.19.3.7070

Corina Marilena Cristache, Eugenia Eftimie Totu, Gheorghe Cristache, Aurelia Cristina Nechifor, Ingrid Ioana Pintilie

Melatonin and Hyaluronic Acid in Periodontal Disease

Abstract:

The aim of the present paper was to highlight the individual effects of melatonin (MEL) and hyaluronic acid (HA) on periodontal structures and repair mechanism and to investigate a possible synergic effect and if each component of the proposed mixture (MEL-HA) would maintain their specific characteristics, when using booth active principles, for a topical application. A comprehensive review of the recent literature focusing on the role of MEL and HA in periodontal therapy, as well as on the use of both active compounds and possible synergic effect, have been conducted. An experimental investigation, using the FT-IR analysis, both the individual spectra of each component and the complex matrix obtained was performed. The experimental data obtained from our study proved that no structural changes occurred at the level of the functional groups of the components. Therefore, it is expected that the obtained formulation to be highly efficient for the treatment of periodontal disease, as it would combine the specific local action of MEL and HA.
Keywords:
Melatonin; hyaluronic acid; synergy; periodontal disease; FT-IR analysis

Issue: 2019, Volume 70, Issue 3
Pages: 1089-1093
Publication date: 2019/4/15
https://doi.org/10.37358/RC.19.3.7070
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Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
CRISTACHE, C.M., TOTU, E.E., CRISTACHE, G., NECHIFOR, A.C., PINTILIE, I.I., Melatonin and Hyaluronic Acid in Periodontal Disease, Rev. Chim., 70(3), 2019, 1089-1093.

Vancouver
Cristache CM, Totu EE, Cristache G, Nechifor AC, Pintilie II. Melatonin and Hyaluronic Acid in Periodontal Disease. Rev. Chim.[internet]. 2019 Mar;70(3):1089-1093. Available from: https://doi.org/10.37358/RC.19.3.7070


APA 6th edition
Cristache, C.M., Totu, E.E., Cristache, G., Nechifor, A.C. & Pintilie, I.I. (2019). Melatonin and Hyaluronic Acid in Periodontal Disease. Revista de Chimie, 70(3), 1089-1093. https://doi.org/10.37358/RC.19.3.7070


Harvard
Cristache, C.M., Totu, E.E., Cristache, G., Nechifor, A.C., Pintilie, I.I. (2019). 'Melatonin and Hyaluronic Acid in Periodontal Disease', Revista de Chimie, 70(3), pp. 1089-1093. https://doi.org/10.37358/RC.19.3.7070


IEEE
C.M. Cristache, E.E. Totu, G. Cristache, A.C. Nechifor, I.I. Pintilie, "Melatonin and Hyaluronic Acid in Periodontal Disease". Revista de Chimie, vol. 70, no. 3, pp. 1089-1093, 2019. [online]. https://doi.org/10.37358/RC.19.3.7070


Text
Corina Marilena Cristache, Eugenia Eftimie Totu, Gheorghe Cristache, Aurelia Cristina Nechifor, Ingrid Ioana Pintilie,
Melatonin and Hyaluronic Acid in Periodontal Disease,
Revista de Chimie,
Volume 70, Issue 3,
2019,
Pages 1089-1093,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.3.7070.
(https://revistadechimie.ro/Articles.asp?ID=7070)
Keywords: Melatonin; hyaluronic acid; synergy; periodontal disease; FT-IR analysis


RIS
TY - JOUR
T1 - Melatonin and Hyaluronic Acid in Periodontal Disease
A1 - Cristache, Corina Marilena
A2 - Totu, Eugenia Eftimie
A3 - Cristache, Gheorghe
A4 - Nechifor, Aurelia Cristina
A5 - Pintilie, Ingrid Ioana
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 3
SP - 1089
EP - 1093
UR - https://doi.org/10.37358/RC.19.3.7070
KW - Melatonin
KW - hyaluronic acid
KW - synergy
KW - periodontal disease
KW - FT-IR analysis
ER -


BibTex
@article{RevCh2019P1089,
author = {Cristache Corina Marilena and Totu Eugenia Eftimie and Cristache Gheorghe and Nechifor Aurelia Cristina and Pintilie Ingrid Ioana},
title = {Melatonin and Hyaluronic Acid in Periodontal Disease},
journal = {Revista de Chimie},
volume = {70},
number = {3},
pages = {1089-1093},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.3.7070},
url = {https://revistadechimie.ro/Articles.asp?ID=7070}
}
 
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