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Cite as: Rev. Chim.
https://doi.org/10.37358/Rev.Chim.1949

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Revista de Chimie (Rev. Chim.), Year 2019, Volume 70, Issue 4, 1298-1301

https://doi.org/10.37358/RC.19.4.7113

Ciprian Mihai Gindac, Ovidiu Horea Bedreag, Laura Alexandra Nussbaum, Iulia Bianca Micu Serbu, Roxana Folescu, Mirela Grigoras, Lavinia Maria Hogea, Mihaela Adriana Simu, Viorel Lupu, Mihaela Boanca, Dorel Sandesc

Mathematical Model for Reducing the Concentration of a Chemical Substance Applicable in the Procedures of Plasmatic Treatment

Abstract:

The objective was to study the correlation between the mathematical form of a chemical that we want to lower its initial concentration by the regressive method and the purging of the body’s toxic present chemicals that need to be eliminated. We developed a chemical model, by which, to a given volume, with a certain (X - concentration %) dissolved substance in a container, the initial solvent, without solvit, is added (concentration 0%) with an equal rhythm to the one that is lost from the used container. The solution that will be lost will contain less and less concentrations of solvit, compared to the initial value X%. At the same time, the concentration of our chemical model will decrease. We applied a regressive mathematical formula to this model in order to calculate the concentration in the container in each moment. At the same time, we conducted treatment sessions in patients in which certain substances need to be eliminated, a procedure that complies with the described chemical model. We have demonstrated that at the same volume of 0% solvit wash, the substance purging with X% concentration is more effective, if the procedure starts with an initial loss of concentrated substance, with ulterior volume replacement. Laboratory data confirms the mathematical model in patients who started the procedure with plasma loss. The developed chemical model demonstrates that the initial loss of substance, hastens the decrease of the initial concentration, especially as the loss is higher at the beginning of the procedure if we use the same replacement volume without the substance in the initial solution. This model can be applied in plasma treatment methods in order to study the patient’s safety and the amount of plasma the patient can lose at the beginning.
Keywords:
mathematical model; TPE (therapeutical plasma exchange); volume replacement; plasma purge

Issue: 2019, Volume 70, Issue 4
Pages: 1298-1301
Publication date: 2019/5/15
https://doi.org/10.37358/RC.19.4.7113
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Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
GINDAC, C.M., BEDREAG, O.H., NUSSBAUM, L.A., SERBU, I.B.M., FOLESCU, R., GRIGORAS, M., HOGEA, L.M., SIMU, M.A., LUPU, V., BOANCA, M., SANDESC, D., Mathematical Model for Reducing the Concentration of a Chemical Substance Applicable in the Procedures of Plasmatic Treatment, Rev. Chim., 70(4), 2019, 1298-1301.

Vancouver
Gindac CM, Bedreag OH, Nussbaum LA, Serbu IBM, Folescu R, Grigoras M, Hogea LM, Simu MA, Lupu V, Boanca M, Sandesc D. Mathematical Model for Reducing the Concentration of a Chemical Substance Applicable in the Procedures of Plasmatic Treatment. Rev. Chim.[internet]. 2019 Apr;70(4):1298-1301. Available from: https://doi.org/10.37358/RC.19.4.7113


APA 6th edition
Gindac, C.M., Bedreag, O.H., Nussbaum, L.A., Serbu, I.B.M., Folescu, R., Grigoras, M.,... Sandesc, D. (2019). Mathematical Model for Reducing the Concentration of a Chemical Substance Applicable in the Procedures of Plasmatic Treatment. Revista de Chimie, 70(4), 1298-1301. https://doi.org/10.37358/RC.19.4.7113


Harvard
Gindac, C.M., Bedreag, O.H., Nussbaum, L.A., Serbu, I.B.M., Folescu, R., Grigoras, M., Hogea, L.M., Simu, M.A., Lupu, V., Boanca, M., Sandesc, D. (2019). 'Mathematical Model for Reducing the Concentration of a Chemical Substance Applicable in the Procedures of Plasmatic Treatment', Revista de Chimie, 70(4), pp. 1298-1301. https://doi.org/10.37358/RC.19.4.7113


IEEE
C.M. Gindac, O.H. Bedreag, L.A. Nussbaum, I.B.M. Serbu, R. Folescu, M. Grigoras, L.M. Hogea, M.A. Simu, V. Lupu, M. Boanca, D. Sandesc, "Mathematical Model for Reducing the Concentration of a Chemical Substance Applicable in the Procedures of Plasmatic Treatment". Revista de Chimie, vol. 70, no. 4, pp. 1298-1301, 2019. [online]. https://doi.org/10.37358/RC.19.4.7113


Text
Ciprian Mihai Gindac, Ovidiu Horea Bedreag, Laura Alexandra Nussbaum, Iulia Bianca Micu Serbu, Roxana Folescu, Mirela Grigoras, Lavinia Maria Hogea, Mihaela Adriana Simu, Viorel Lupu, Mihaela Boanca, Dorel Sandesc,
Mathematical Model for Reducing the Concentration of a Chemical Substance Applicable in the Procedures of Plasmatic Treatment,
Revista de Chimie,
Volume 70, Issue 4,
2019,
Pages 1298-1301,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.4.7113.
(https://revistadechimie.ro/Articles.asp?ID=7113)
Keywords: mathematical model; TPE (therapeutical plasma exchange); volume replacement; plasma purge


RIS
TY - JOUR
T1 - Mathematical Model for Reducing the Concentration of a Chemical Substance Applicable in the Procedures of Plasmatic Treatment
A1 - Gindac, Ciprian Mihai
A2 - Bedreag, Ovidiu Horea
A3 - Nussbaum, Laura Alexandra
A4 - Serbu, Iulia Bianca Micu
A5 - Folescu, Roxana
A6 - Grigoras, Mirela
A7 - Hogea, Lavinia Maria
A8 - Simu, Mihaela Adriana
A9 - Lupu, Viorel
A10 - Boanca, Mihaela
A11 - Sandesc, Dorel
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 4
SP - 1298
EP - 1301
UR - https://doi.org/10.37358/RC.19.4.7113
KW - mathematical model
KW - TPE (therapeutical plasma exchange)
KW - volume replacement
KW - plasma purge
ER -


BibTex
@article{RevCh2019P1298,
author = {Gindac Ciprian Mihai and Bedreag Ovidiu Horea and Nussbaum Laura Alexandra and Serbu Iulia Bianca Micu and Folescu Roxana and Grigoras Mirela and Hogea Lavinia Maria and Simu Mihaela Adriana and Lupu Viorel and Boanca Mihaela and Sandesc Dorel},
title = {Mathematical Model for Reducing the Concentration of a Chemical Substance Applicable in the Procedures of Plasmatic Treatment},
journal = {Revista de Chimie},
volume = {70},
number = {4},
pages = {1298-1301},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.4.7113},
url = {https://revistadechimie.ro/Articles.asp?ID=7113}
}
 
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