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https://doi.org/10.37358/Rev.Chim.1949

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Revista de Chimie (Rev. Chim.), Year 2019, Volume 70, Issue 4, 1364-1367

https://doi.org/10.37358/RC.19.4.7128

Lucian Hritcu, Sara Abidar, Gabriela Dumitru, Razvan Stefan Boiangiu, Mohamad Nhiri, Ion Sandu, Elena Todirascu-Ciornea

Ceratonia Siliqua Methanolic Extract on 6-OHDA Zebrafish Model Antiacetylcholinesterase and Anxiolytic Profile

Abstract:

Anxiety and depression are the most common mental disorders that increase morbidity in the world, and recent data (World Health Organization - WHO) show that over 322 million people suffer from depression and anxiety, especially women being more exposed than men. 6-Hydroxydopamine (6-OHDA) is a catecholaminergic neurotoxin which is formed endogenously in patients diagnosed with Parkinson’s disease and has two mechanisms of action. Thus, it easily forms free radicals and is a potent inhibitor of the mitochondrial respiratory chain complexes I and IV. The treatments administration of 6-OHDA (160 ìM) and Ceratonia siliqua L. methanolic extract (0.1 mg/mL, 0.3 mg/mL and 1.0 mg/mL) in Danio rerio specimens affected the acetylcholinesterase activity (AChE) and anxiolytic profile in close correlation with the dose of administered extract, the group with significant differences being the treated one with 6-OHDA alone.
Keywords:
6-hydroxydopamine; acetylcholinesterase; anxiety; carob

Issue: 2019, Volume 70, Issue 4
Pages: 1364-1367
Publication date: 2019/5/15
https://doi.org/10.37358/RC.19.4.7128
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Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
HRITCU, L., ABIDAR, S., DUMITRU, G., BOIANGIU, R.S., NHIRI, M., SANDU, I., TODIRASCU-CIORNEA, E., Ceratonia Siliqua Methanolic Extract on 6-OHDA Zebrafish Model Antiacetylcholinesterase and Anxiolytic Profile, Rev. Chim., 70(4), 2019, 1364-1367.

Vancouver
Hritcu L, Abidar S, Dumitru G, Boiangiu RS, Nhiri M, Sandu I, Todirascu-Ciornea E. Ceratonia Siliqua Methanolic Extract on 6-OHDA Zebrafish Model Antiacetylcholinesterase and Anxiolytic Profile. Rev. Chim.[internet]. 2019 Apr;70(4):1364-1367. Available from: https://doi.org/10.37358/RC.19.4.7128


APA 6th edition
Hritcu, L., Abidar, S., Dumitru, G., Boiangiu, R.S., Nhiri, M., Sandu, I. & Todirascu-Ciornea, E. (2019). Ceratonia Siliqua Methanolic Extract on 6-OHDA Zebrafish Model Antiacetylcholinesterase and Anxiolytic Profile. Revista de Chimie, 70(4), 1364-1367. https://doi.org/10.37358/RC.19.4.7128


Harvard
Hritcu, L., Abidar, S., Dumitru, G., Boiangiu, R.S., Nhiri, M., Sandu, I., Todirascu-Ciornea, E. (2019). 'Ceratonia Siliqua Methanolic Extract on 6-OHDA Zebrafish Model Antiacetylcholinesterase and Anxiolytic Profile', Revista de Chimie, 70(4), pp. 1364-1367. https://doi.org/10.37358/RC.19.4.7128


IEEE
L. Hritcu, S. Abidar, G. Dumitru, R.S. Boiangiu, M. Nhiri, I. Sandu, E. Todirascu-Ciornea, "Ceratonia Siliqua Methanolic Extract on 6-OHDA Zebrafish Model Antiacetylcholinesterase and Anxiolytic Profile". Revista de Chimie, vol. 70, no. 4, pp. 1364-1367, 2019. [online]. https://doi.org/10.37358/RC.19.4.7128


Text
Lucian Hritcu, Sara Abidar, Gabriela Dumitru, Razvan Stefan Boiangiu, Mohamad Nhiri, Ion Sandu, Elena Todirascu-Ciornea,
Ceratonia Siliqua Methanolic Extract on 6-OHDA Zebrafish Model Antiacetylcholinesterase and Anxiolytic Profile,
Revista de Chimie,
Volume 70, Issue 4,
2019,
Pages 1364-1367,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.4.7128.
(https://revistadechimie.ro/Articles.asp?ID=7128)
Keywords: 6-hydroxydopamine; acetylcholinesterase; anxiety; carob


RIS
TY - JOUR
T1 - Ceratonia Siliqua Methanolic Extract on 6-OHDA Zebrafish Model Antiacetylcholinesterase and Anxiolytic Profile
A1 - Hritcu, Lucian
A2 - Abidar, Sara
A3 - Dumitru, Gabriela
A4 - Boiangiu, Razvan Stefan
A5 - Nhiri, Mohamad
A6 - Sandu, Ion
A7 - Todirascu-Ciornea, Elena
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 4
SP - 1364
EP - 1367
UR - https://doi.org/10.37358/RC.19.4.7128
KW - 6-hydroxydopamine
KW - acetylcholinesterase
KW - anxiety
KW - carob
ER -


BibTex
@article{RevCh2019P1364,
author = {Hritcu Lucian and Abidar Sara and Dumitru Gabriela and Boiangiu Razvan Stefan and Nhiri Mohamad and Sandu Ion and Todirascu-Ciornea Elena},
title = {Ceratonia Siliqua Methanolic Extract on 6-OHDA Zebrafish Model Antiacetylcholinesterase and Anxiolytic Profile},
journal = {Revista de Chimie},
volume = {70},
number = {4},
pages = {1364-1367},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.4.7128},
url = {https://revistadechimie.ro/Articles.asp?ID=7128}
}
 
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