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https://doi.org/10.37358/Rev.Chim.1949

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Revista de Chimie (Rev. Chim.), Year 2019, Volume 70, Issue 4, 1500-1506

https://doi.org/10.37358/RC.19.4.7158

Romina Marina Sima, Dragos Albu, Antoniu Cringu Ionescu, Mihai Dimitriu, Mihai Popescu, Dana-Rodica Tomescu, Radu Chicea, Iuliana Ceausu, Ioan-Iulian Iordache, Mircea-Octavian Poenaru, Alexandra Matei, Alina Calin, Liana Ples

The Impact of Ulipristal Acetate (UPA) versus Dienogest on Pain Related to Endometriomas Evaluated with Visual Analogue Scale (VAS)

Abstract:

Visual analogue scale (VAS) is a psychometric scale applied to measure subjective characteristics. The purpose of our study was to evaluate the efficiency of Ulipristal acetate (UPA) compared with Dienogest for endometriomas related pain using VAS. We performed a randomized study on women with symptomatic endometriomas. The study was realized between January 2016-December 2018. The patients were randomized in two groups: Group A- that received UPA in doses of 5 mg daily for 12-13 weeks and Group B that received 2 mg Dienogest for 12-13 weeks. Each group received de VAS (Visual Analogue Scale) questionnaire before and after treatment. 70 women wereincluded in the study with 35 patients for each group. The age the mean age was 30.20 years. For Numeric Rating Scale before treatment in the group with UPA the median value was 6 (CI= 5.26, 6.51) and for group B the median was 5 (CI= 5.13, 5.66). After treatment for group A the median value was 4 (CI= 3.58, 4.29) and for group B the median value 4 (CI= 4.23, 4.6). For FRS before treatment in the group with UPA median value was 6 (CI= 5.87, 6.58) and for the group B median was 6 (CI= 6.16, 6.57). After treatment for group A the median value was 4 (CI= 4.12, 4.73) and for group B the median value 5 (CI= 4.9, 5.06). The pain significantly improved for group A. (p[ 0.05) VAS represent a good method to evaluate the quality of pain for patients with endometriomas. The UPA and Dienogest treatment improve the VAS parameters with better results for UPA in the present study.
Keywords:
endometriosis; VAS; dienogest; ulipristal; pain

Issue: 2019, Volume 70, Issue 4
Pages: 1500-1506
Publication date: 2019/5/15
https://doi.org/10.37358/RC.19.4.7158
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Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
SIMA, R.M., ALBU, D., IONESCU, A.C., DIMITRIU, M., POPESCU, M., TOMESCU, D., CHICEA, R., CEAUSU, I., IORDACHE, I., POENARU, M., MATEI, A., CALIN, A., PLES, L., The Impact of Ulipristal Acetate (UPA) versus Dienogest on Pain Related to Endometriomas Evaluated with Visual Analogue Scale (VAS), Rev. Chim., 70(4), 2019, 1500-1506.

Vancouver
Sima RM, Albu D, Ionescu AC, Dimitriu M, Popescu M, Tomescu D, Chicea R, Ceausu I, Iordache I, Poenaru M, Matei A, Calin A, Ples L. The Impact of Ulipristal Acetate (UPA) versus Dienogest on Pain Related to Endometriomas Evaluated with Visual Analogue Scale (VAS). Rev. Chim.[internet]. 2019 Apr;70(4):1500-1506. Available from: https://doi.org/10.37358/RC.19.4.7158


APA 6th edition
Sima, R.M., Albu, D., Ionescu, A.C., Dimitriu, M., Popescu, M., Tomescu, D.,... Ples, L. (2019). The Impact of Ulipristal Acetate (UPA) versus Dienogest on Pain Related to Endometriomas Evaluated with Visual Analogue Scale (VAS). Revista de Chimie, 70(4), 1500-1506. https://doi.org/10.37358/RC.19.4.7158


Harvard
Sima, R.M., Albu, D., Ionescu, A.C., Dimitriu, M., Popescu, M., Tomescu, D., Chicea, R., Ceausu, I., Iordache, I., Poenaru, M., Matei, A., Calin, A., Ples, L. (2019). 'The Impact of Ulipristal Acetate (UPA) versus Dienogest on Pain Related to Endometriomas Evaluated with Visual Analogue Scale (VAS)', Revista de Chimie, 70(4), pp. 1500-1506. https://doi.org/10.37358/RC.19.4.7158


IEEE
R.M. Sima, D. Albu, A.C. Ionescu, M. Dimitriu, M. Popescu, D. Tomescu, R. Chicea, I. Ceausu, I. Iordache, M. Poenaru, A. Matei, A. Calin, L. Ples, "The Impact of Ulipristal Acetate (UPA) versus Dienogest on Pain Related to Endometriomas Evaluated with Visual Analogue Scale (VAS)". Revista de Chimie, vol. 70, no. 4, pp. 1500-1506, 2019. [online]. https://doi.org/10.37358/RC.19.4.7158


Text
Romina Marina Sima, Dragos Albu, Antoniu Cringu Ionescu, Mihai Dimitriu, Mihai Popescu, Dana-Rodica Tomescu, Radu Chicea, Iuliana Ceausu, Ioan-Iulian Iordache, Mircea-Octavian Poenaru, Alexandra Matei, Alina Calin, Liana Ples,
The Impact of Ulipristal Acetate (UPA) versus Dienogest on Pain Related to Endometriomas Evaluated with Visual Analogue Scale (VAS),
Revista de Chimie,
Volume 70, Issue 4,
2019,
Pages 1500-1506,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.4.7158.
(https://revistadechimie.ro/Articles.asp?ID=7158)
Keywords: endometriosis; VAS; dienogest; ulipristal; pain


RIS
TY - JOUR
T1 - The Impact of Ulipristal Acetate (UPA) versus Dienogest on Pain Related to Endometriomas Evaluated with Visual Analogue Scale (VAS)
A1 - Sima, Romina Marina
A2 - Albu, Dragos
A3 - Ionescu, Antoniu Cringu
A4 - Dimitriu, Mihai
A5 - Popescu, Mihai
A6 - Tomescu, Dana-Rodica
A7 - Chicea, Radu
A8 - Ceausu, Iuliana
A9 - Iordache, Ioan-Iulian
A10 - Poenaru, Mircea-Octavian
A11 - Matei, Alexandra
A12 - Calin, Alina
A13 - Ples, Liana
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 4
SP - 1500
EP - 1506
UR - https://doi.org/10.37358/RC.19.4.7158
KW - endometriosis
KW - VAS
KW - dienogest
KW - ulipristal
KW - pain
ER -


BibTex
@article{RevCh2019P1500,
author = {Sima Romina Marina and Albu Dragos and Ionescu Antoniu Cringu and Dimitriu Mihai and Popescu Mihai and Tomescu Dana-Rodica and Chicea Radu and Ceausu Iuliana and Iordache Ioan-Iulian and Poenaru Mircea-Octavian and Matei Alexandra and Calin Alina and Ples Liana},
title = {The Impact of Ulipristal Acetate (UPA) versus Dienogest on Pain Related to Endometriomas Evaluated with Visual Analogue Scale (VAS)},
journal = {Revista de Chimie},
volume = {70},
number = {4},
pages = {1500-1506},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.4.7158},
url = {https://revistadechimie.ro/Articles.asp?ID=7158}
}
 
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