A Card Double Face: Compounds Functionality and Synergy of a Topical Treatment Proposed for Oral Health Improvement in Periodontal Disease

Totu, Eugenia Eftimie; Cristache, Corina Marilena; Buga, Roxana; Dumitru, Florina; Totu, Tiberiu

Eugenia Eftimie Totu, Corina Marilena Cristache, Roxana Buga, Florina Dumitru, Tiberiu Totu

A Card Double Face: Compounds Functionality and Synergy of a Topical Treatment Proposed for Oral Health Improvement in Periodontal Disease

Abstract:

The application of an active mixture of melatonin, hyaluronic acid and tetracycline, as antibiotic adjuvant, for scaling and root planing in periodontal disease is exploited. The hyaluronic acid gel has been used as matrix for this topical mixture. The mixture of active ingredients has been structurally studied applying UV-Vis and FT-IR spectrophotometry and fluorescence microscopy. Our target was to put in evidence if melatonin, hyaluronic acid and tetracycline were preserving their specific characteristics when they would be mixed together. The recorded results are encouraging as each active compound maintains its characteristic functional groups imparting their biological action. The improved topical treatment based on melatonin, hyaluronic acid and tetracycline is presenting itself as a promising candidate for improving the oral health for patients with periodontitis.

Keywords:
melatonin; hyaluronic acid; tetracycline; oral health; topical treatment

Issue: 2019, Volume 70, Issue 5

Pages: 1551-1557

Publication date: 2019/6/15

https://doi.org/10.37358/RC.19.5.7167

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
TOTU, E.E., CRISTACHE, C.M., BUGA, R., DUMITRU, F., TOTU, T., A Card Double Face: Compounds Functionality and Synergy of a Topical Treatment Proposed for Oral Health Improvement in Periodontal Disease, Rev. Chim., 70(5), 2019, 1551-1557.

Vancouver
Totu EE, Cristache CM, Buga R, Dumitru F, Totu T. A Card Double Face: Compounds Functionality and Synergy of a Topical Treatment Proposed for Oral Health Improvement in Periodontal Disease. Rev. Chim.[internet]. 2019 May;70(5):1551-1557. Available from: https://doi.org/10.37358/RC.19.5.7167

APA 6th edition
Totu, E.E., Cristache, C.M., Buga, R., Dumitru, F. & Totu, T. (2019). A Card Double Face: Compounds Functionality and Synergy of a Topical Treatment Proposed for Oral Health Improvement in Periodontal Disease. Revista de Chimie, 70(5), 1551-1557. https://doi.org/10.37358/RC.19.5.7167

Harvard
Totu, E.E., Cristache, C.M., Buga, R., Dumitru, F., Totu, T. (2019). 'A Card Double Face: Compounds Functionality and Synergy of a Topical Treatment Proposed for Oral Health Improvement in Periodontal Disease', Revista de Chimie, 70(5), pp. 1551-1557. https://doi.org/10.37358/RC.19.5.7167

IEEE
E.E. Totu, C.M. Cristache, R. Buga, F. Dumitru, T. Totu, "A Card Double Face: Compounds Functionality and Synergy of a Topical Treatment Proposed for Oral Health Improvement in Periodontal Disease". Revista de Chimie, vol. 70, no. 5, pp. 1551-1557, 2019. [online]. https://doi.org/10.37358/RC.19.5.7167

Text
Eugenia Eftimie Totu, Corina Marilena Cristache, Roxana Buga, Florina Dumitru, Tiberiu Totu,
A Card Double Face: Compounds Functionality and Synergy of a Topical Treatment Proposed for Oral Health Improvement in Periodontal Disease,
Revista de Chimie,
Volume 70, Issue 5,
2019,
Pages 1551-1557,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.5.7167.
(https://revistadechimie.ro/Articles.asp?ID=7167)
Keywords: melatonin; hyaluronic acid; tetracycline; oral health; topical treatment

RIS
TY - JOUR
T1 - A Card Double Face: Compounds Functionality and Synergy of a Topical Treatment Proposed for Oral Health Improvement in Periodontal Disease
A1 - Totu, Eugenia Eftimie
A2 - Cristache, Corina Marilena
A3 - Buga, Roxana
A4 - Dumitru, Florina
A5 - Totu, Tiberiu
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 5
SP - 1551
EP - 1557
UR - https://doi.org/10.37358/RC.19.5.7167
KW - melatonin
KW - hyaluronic acid
KW - tetracycline
KW - oral health
KW - topical treatment
ER -

BibTex
@article{RevCh2019P1551,
author = {Totu Eugenia Eftimie and Cristache Corina Marilena and Buga Roxana and Dumitru Florina and Totu Tiberiu},
title = {A Card Double Face: Compounds Functionality and Synergy of a Topical Treatment Proposed for Oral Health Improvement in Periodontal Disease},
journal = {Revista de Chimie},
volume = {70},
number = {5},
pages = {1551-1557},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.5.7167},
url = {https://revistadechimie.ro/Articles.asp?ID=7167}
}

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