Metabolic Syndrome Among Patients with Rheumatoid Arthritis and the Correlation with Disease Activity

Ene, Cristina Gabriela; Mitroi, Mihaela; Vladu, Ionela Mihaela; Radu, Lucretiu; Cojan, Tiberiu Stefanita Tenea; Predescu, Anca Mihaela; Bunescu, Marius Gabriel

Cristina Gabriela Ene, Mihaela Mitroi, Ionela Mihaela Vladu, Lucretiu Radu, Tiberiu Stefanita Tenea Cojan, Anca Mihaela Predescu, Marius Gabriel Bunescu

Metabolic Syndrome Among Patients with Rheumatoid Arthritis and the Correlation with Disease Activity

Abstract:

Rheumatoid arthritis is a systemic inflamatory disease that affects primarily the synovial joints and it is associated with a progressive disability and a important socio-economic burden. [1] Although the main characteristic is the joint involvement, it is important to remember that RA is a disorder with systemic involvement mainly due to it’s chronic inflamation. Patients with RA have a higher risk of cardio-vascular mortality that in general population. There are numerous studies that sugest that inflamation plays a key”role in the develompent of aterosclerosis and heart disease, therefore a better understanding of the inflamatory response in RA may lead to better outcomes for patients with RA. Metabolic Syndrome is described as a congregate of major risk factors for cardiovascular diseases (CVD): Diabetes and raised fasting plasma glucose, abdominal obesity, high cholesterol and high blood presure[2]. The clustering of CVD risk factors that typifies the metabolic syndrome is now considered to be the driving force for a new CVD epidemic [3]. The conducted study aims to assess and evaluate the presence of metabolic syndrome (MetS) in RA patients. 120 patients with RA (89 women and 31 men) and 120 (85 women and 35 men) patients without RA were included in the study. The prevalence of MetS in RA patients was 39.16% and 22.5% for the control group. RA patients with MetS had significantly higher disease activity score of 28 joints index (DAS28-ESR) than patients without MetS ( 3.70 ± 0.644 vs. 3.35 ±0.725; p=0.006).

Keywords:
Rheumatoid arthritis; Metabolic Syndrome; inflamation; disease activity; cardiovascular risk

Issue: 2019, Volume 70, Issue 6

Pages: 2108-2111

Publication date: 2019/7/15

https://doi.org/10.37358/RC.19.6.7285

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
ENE, C.G., MITROI, M., VLADU, I.M., RADU, L., COJAN, T.S.T., PREDESCU, A.M., BUNESCU, M.G., Metabolic Syndrome Among Patients with Rheumatoid Arthritis and the Correlation with Disease Activity, Rev. Chim., 70(6), 2019, 2108-2111.

Vancouver
Ene CG, Mitroi M, Vladu IM, Radu L, Cojan TST, Predescu AM, Bunescu MG. Metabolic Syndrome Among Patients with Rheumatoid Arthritis and the Correlation with Disease Activity. Rev. Chim.[internet]. 2019 Jun;70(6):2108-2111. Available from: https://doi.org/10.37358/RC.19.6.7285

APA 6th edition
Ene, C.G., Mitroi, M., Vladu, I.M., Radu, L., Cojan, T.S.T., Predescu, A.M. & Bunescu, M.G. (2019). Metabolic Syndrome Among Patients with Rheumatoid Arthritis and the Correlation with Disease Activity. Revista de Chimie, 70(6), 2108-2111. https://doi.org/10.37358/RC.19.6.7285

Harvard
Ene, C.G., Mitroi, M., Vladu, I.M., Radu, L., Cojan, T.S.T., Predescu, A.M., Bunescu, M.G. (2019). 'Metabolic Syndrome Among Patients with Rheumatoid Arthritis and the Correlation with Disease Activity', Revista de Chimie, 70(6), pp. 2108-2111. https://doi.org/10.37358/RC.19.6.7285

IEEE
C.G. Ene, M. Mitroi, I.M. Vladu, L. Radu, T.S.T. Cojan, A.M. Predescu, M.G. Bunescu, "Metabolic Syndrome Among Patients with Rheumatoid Arthritis and the Correlation with Disease Activity". Revista de Chimie, vol. 70, no. 6, pp. 2108-2111, 2019. [online]. https://doi.org/10.37358/RC.19.6.7285

Text
Cristina Gabriela Ene, Mihaela Mitroi, Ionela Mihaela Vladu, Lucretiu Radu, Tiberiu Stefanita Tenea Cojan, Anca Mihaela Predescu, Marius Gabriel Bunescu,
Metabolic Syndrome Among Patients with Rheumatoid Arthritis and the Correlation with Disease Activity,
Revista de Chimie,
Volume 70, Issue 6,
2019,
Pages 2108-2111,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.6.7285.
(https://revistadechimie.ro/Articles.asp?ID=7285)
Keywords: Rheumatoid arthritis; Metabolic Syndrome; inflamation; disease activity; cardiovascular risk

RIS
TY - JOUR
T1 - Metabolic Syndrome Among Patients with Rheumatoid Arthritis and the Correlation with Disease Activity
A1 - Ene, Cristina Gabriela
A2 - Mitroi, Mihaela
A3 - Vladu, Ionela Mihaela
A4 - Radu, Lucretiu
A5 - Cojan, Tiberiu Stefanita Tenea
A6 - Predescu, Anca Mihaela
A7 - Bunescu, Marius Gabriel
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 6
SP - 2108
EP - 2111
UR - https://doi.org/10.37358/RC.19.6.7285
KW - Rheumatoid arthritis
KW - Metabolic Syndrome
KW - inflamation
KW - disease activity
KW - cardiovascular risk
ER -

BibTex
@article{RevCh2019P2108,
author = {Ene Cristina Gabriela and Mitroi Mihaela and Vladu Ionela Mihaela and Radu Lucretiu and Cojan Tiberiu Stefanita Tenea and Predescu Anca Mihaela and Bunescu Marius Gabriel},
title = {Metabolic Syndrome Among Patients with Rheumatoid Arthritis and the Correlation with Disease Activity},
journal = {Revista de Chimie},
volume = {70},
number = {6},
pages = {2108-2111},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.6.7285},
url = {https://revistadechimie.ro/Articles.asp?ID=7285}
}

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