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REVISTA DE CHIMIE
Cite as: Rev. Chim.
https://doi.org/10.37358/Rev.Chim.1949

OSIM Nr. R102355
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Revista de Chimie (Rev. Chim.), Year 2019, Volume 70, Issue 6, 2222-2224

https://doi.org/10.37358/RC.19.6.7309

Valentina Ghimpau, Cristina Lungulescu, Alexandru Florian Grecu, Dan Ionut Gheonea, Mihaela Danciulescu, Victor Gheorman, Veronica Gheorman, Simona Ruxandra Volovat, Cristian Virgil Lungulescu

Correlations Between Distinct Ras Mutations and Response to Bevacizumab in Patients with Colo-rectal Cancer

Abstract:

CRC is currently ranked third among frequently diagnosed malignancies. Mutations in exons 2,3 and 4 of the KRAS and NRAS genes were detected using a targeted resequencingassay from paraffin embedded tissue from patients’ biopsies samples. The following data was recorded for each patient: baseline information - age and sex - as well as diagnosis, cancer localization, disease stage and laboratory parameters.In our study group we could not find statistically significant differences regarding distinct mutations and the progression free survival (p=0.34]0.05) for patients treated with an anti-angiogenic therapy.
Keywords:
colorectal cancer; RAS; mutations; bevacizumab

Issue: 2019, Volume 70, Issue 6
Pages: 2222-2224
Publication date: 2019/7/15
https://doi.org/10.37358/RC.19.6.7309
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Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
GHIMPAU, V., LUNGULESCU, C., GRECU, A.F., GHEONEA, D.I., DANCIULESCU, M., GHEORMAN, V., GHEORMAN, V., VOLOVAT, S.R., LUNGULESCU, C.V., Correlations Between Distinct Ras Mutations and Response to Bevacizumab in Patients with Colo-rectal Cancer, Rev. Chim., 70(6), 2019, 2222-2224.

Vancouver
Ghimpau V, Lungulescu C, Grecu AF, Gheonea DI, Danciulescu M, Gheorman V, Gheorman V, Volovat SR, Lungulescu CV. Correlations Between Distinct Ras Mutations and Response to Bevacizumab in Patients with Colo-rectal Cancer. Rev. Chim.[internet]. 2019 Jun;70(6):2222-2224. Available from: https://doi.org/10.37358/RC.19.6.7309


APA 6th edition
Ghimpau, V., Lungulescu, C., Grecu, A.F., Gheonea, D.I., Danciulescu, M., Gheorman, V.,... Lungulescu, C.V. (2019). Correlations Between Distinct Ras Mutations and Response to Bevacizumab in Patients with Colo-rectal Cancer. Revista de Chimie, 70(6), 2222-2224. https://doi.org/10.37358/RC.19.6.7309


Harvard
Ghimpau, V., Lungulescu, C., Grecu, A.F., Gheonea, D.I., Danciulescu, M., Gheorman, V., Gheorman, V., Volovat, S.R., Lungulescu, C.V. (2019). 'Correlations Between Distinct Ras Mutations and Response to Bevacizumab in Patients with Colo-rectal Cancer', Revista de Chimie, 70(6), pp. 2222-2224. https://doi.org/10.37358/RC.19.6.7309


IEEE
V. Ghimpau, C. Lungulescu, A.F. Grecu, D.I. Gheonea, M. Danciulescu, V. Gheorman, V. Gheorman, S.R. Volovat, C.V. Lungulescu, "Correlations Between Distinct Ras Mutations and Response to Bevacizumab in Patients with Colo-rectal Cancer". Revista de Chimie, vol. 70, no. 6, pp. 2222-2224, 2019. [online]. https://doi.org/10.37358/RC.19.6.7309


Text
Valentina Ghimpau, Cristina Lungulescu, Alexandru Florian Grecu, Dan Ionut Gheonea, Mihaela Danciulescu, Victor Gheorman, Veronica Gheorman, Simona Ruxandra Volovat, Cristian Virgil Lungulescu,
Correlations Between Distinct Ras Mutations and Response to Bevacizumab in Patients with Colo-rectal Cancer,
Revista de Chimie,
Volume 70, Issue 6,
2019,
Pages 2222-2224,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.6.7309.
(https://revistadechimie.ro/Articles.asp?ID=7309)
Keywords: colorectal cancer; RAS; mutations; bevacizumab


RIS
TY - JOUR
T1 - Correlations Between Distinct Ras Mutations and Response to Bevacizumab in Patients with Colo-rectal Cancer
A1 - Ghimpau, Valentina
A2 - Lungulescu, Cristina
A3 - Grecu, Alexandru Florian
A4 - Gheonea, Dan Ionut
A5 - Danciulescu, Mihaela
A6 - Gheorman, Victor
A7 - Gheorman, Veronica
A8 - Volovat, Simona Ruxandra
A9 - Lungulescu, Cristian Virgil
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 6
SP - 2222
EP - 2224
UR - https://doi.org/10.37358/RC.19.6.7309
KW - colorectal cancer
KW - RAS
KW - mutations
KW - bevacizumab
ER -


BibTex
@article{RevCh2019P2222,
author = {Ghimpau Valentina and Lungulescu Cristina and Grecu Alexandru Florian and Gheonea Dan Ionut and Danciulescu Mihaela and Gheorman Victor and Gheorman Veronica and Volovat Simona Ruxandra and Lungulescu Cristian Virgil},
title = {Correlations Between Distinct Ras Mutations and Response to Bevacizumab in Patients with Colo-rectal Cancer},
journal = {Revista de Chimie},
volume = {70},
number = {6},
pages = {2222-2224},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.6.7309},
url = {https://revistadechimie.ro/Articles.asp?ID=7309}
}
 
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