C-Reactive Protein - A Predictable Biomarker in Ischemic Stroke

Totan, Maria; Antonescu, Elisabeta; Catana, Maria Gabriela; Cernusca-Mitariu, Maria Mihaela; Duica, Lavinia; Roman-Filip, Corina; Comaneanu, Raluca Monica; Cernusca-Mitariu, Sebastian Ioan

Maria Totan, Elisabeta Antonescu, Maria Gabriela Catana, Maria Mihaela Cernusca-Mitariu, Lavinia Duica, Corina Roman-Filip, Raluca Monica Comaneanu, Sebastian Ioan Cernusca-Mitariu

C-Reactive Protein - A Predictable Biomarker in Ischemic Stroke

Abstract:

C-reactive protein (CRP) is a non-specific inflammatory marker, correlated with the severity and prognosis of ischemic stroke. We performed a retrospective study in which were included 81 patients diagnosed with acute ischemic stroke admitted between January and July 2017 in the Department of Neurology, Sibiu Emergency Clinical Hospital. CRP values were classified on three levels (0 - 5 mg / L, 5 - 50 mg / l and] 50 mg / l). We examined the correlation between CRP levels according to the type of ischemic (lacunar / territorial) stroke, the degree of motor deficit (quantified by the mRC scale), the associated risk factors and the mortality rate. PCR values above 50 mg / L were found in patients with territorial stroke (15%). Moderate motor deficits predominate, with PCR values ranging from 5-50 mg / L. The most important risk factors found in the patients included in our study were hypertension and atherosclerosis. We made correlations between these risk factors and the PCR values. In most cases with these two risk factors were recorded a mean PCR value (5-50 mg / L).For atherosclerosis the results were statistically significant, p = 0.021. Most patients (56%) had CRP levels ranging from 5 to 50 mg / L. These values recorded highest death rates. PCR it is an important marker of inflammation and it is important to be determined in all patients with acute ischemic stroke, especially which is thought to be correlated with the prognosis of these patients.

Keywords:
C-reactive protein; inflammation; ischemic stroke

Issue: 2019, Volume 70, Issue 6

Pages: 2290-2293

Publication date: 2019/7/15

https://doi.org/10.37358/RC.19.6.7325

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
TOTAN, M., ANTONESCU, E., CATANA, M.G., CERNUSCA-MITARIU, M.M., DUICA, L., ROMAN-FILIP, C., COMANEANU, R.M., CERNUSCA-MITARIU, S.I., C-Reactive Protein - A Predictable Biomarker in Ischemic Stroke, Rev. Chim., 70(6), 2019, 2290-2293.

Vancouver
Totan M, Antonescu E, Catana MG, Cernusca-Mitariu MM, Duica L, Roman-Filip C, Comaneanu RM, Cernusca-Mitariu SI. C-Reactive Protein - A Predictable Biomarker in Ischemic Stroke. Rev. Chim.[internet]. 2019 Jun;70(6):2290-2293. Available from: https://doi.org/10.37358/RC.19.6.7325

APA 6th edition
Totan, M., Antonescu, E., Catana, M.G., Cernusca-Mitariu, M.M., Duica, L., Roman-Filip, C., Comaneanu, R.M. & Cernusca-Mitariu, S.I. (2019). C-Reactive Protein - A Predictable Biomarker in Ischemic Stroke. Revista de Chimie, 70(6), 2290-2293. https://doi.org/10.37358/RC.19.6.7325

Harvard
Totan, M., Antonescu, E., Catana, M.G., Cernusca-Mitariu, M.M., Duica, L., Roman-Filip, C., Comaneanu, R.M., Cernusca-Mitariu, S.I. (2019). 'C-Reactive Protein - A Predictable Biomarker in Ischemic Stroke', Revista de Chimie, 70(6), pp. 2290-2293. https://doi.org/10.37358/RC.19.6.7325

IEEE
M. Totan, E. Antonescu, M.G. Catana, M.M. Cernusca-Mitariu, L. Duica, C. Roman-Filip, R.M. Comaneanu, S.I. Cernusca-Mitariu, "C-Reactive Protein - A Predictable Biomarker in Ischemic Stroke". Revista de Chimie, vol. 70, no. 6, pp. 2290-2293, 2019. [online]. https://doi.org/10.37358/RC.19.6.7325

Text
Maria Totan, Elisabeta Antonescu, Maria Gabriela Catana, Maria Mihaela Cernusca-Mitariu, Lavinia Duica, Corina Roman-Filip, Raluca Monica Comaneanu, Sebastian Ioan Cernusca-Mitariu,
C-Reactive Protein - A Predictable Biomarker in Ischemic Stroke,
Revista de Chimie,
Volume 70, Issue 6,
2019,
Pages 2290-2293,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.6.7325.
(https://revistadechimie.ro/Articles.asp?ID=7325)
Keywords: C-reactive protein; inflammation; ischemic stroke

RIS
TY - JOUR
T1 - C-Reactive Protein - A Predictable Biomarker in Ischemic Stroke
A1 - Totan, Maria
A2 - Antonescu, Elisabeta
A3 - Catana, Maria Gabriela
A4 - Cernusca-Mitariu, Maria Mihaela
A5 - Duica, Lavinia
A6 - Roman-Filip, Corina
A7 - Comaneanu, Raluca Monica
A8 - Cernusca-Mitariu, Sebastian Ioan
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 6
SP - 2290
EP - 2293
UR - https://doi.org/10.37358/RC.19.6.7325
KW - C-reactive protein
KW - inflammation
KW - ischemic stroke
ER -

BibTex
@article{RevCh2019P2290,
author = {Totan Maria and Antonescu Elisabeta and Catana Maria Gabriela and Cernusca-Mitariu Maria Mihaela and Duica Lavinia and Roman-Filip Corina and Comaneanu Raluca Monica and Cernusca-Mitariu Sebastian Ioan},
title = {C-Reactive Protein - A Predictable Biomarker in Ischemic Stroke},
journal = {Revista de Chimie},
volume = {70},
number = {6},
pages = {2290-2293},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.6.7325},
url = {https://revistadechimie.ro/Articles.asp?ID=7325}
}

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