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REVISTA DE CHIMIE
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https://doi.org/10.37358/Rev.Chim.1949

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Revista de Chimie (Rev. Chim.), Year 2019, Volume 70, Issue 7, 2534-2537

https://doi.org/10.37358/RC.19.7.7375

Gladiola Tantaru, Mihai Apostu, Antonia Poiata, Mihai Nichifor, Nela Bibire, Alina Diana Panainte, Madalina Vieriu

Study of Physico-chemical Characteristics and Pharmacological Effects of 1-Ethyl-Salicyldene-bis-Ethylene-Diamine and Its Complex with Mn(II)

Abstract:

The paper presents the synthesis of a new complex combination of a Bis-Schiff base with Mn(II) ions with great potential for antimicrobial and anti-inflammatory activity. A new complex of the Salen-type ligand, 1-ethyl-salicylidene-bis-ethylene diamine was synthetized using Mn(II) ions. The chemical structure was confirmed through 1H-NMR and IR spectroscopy. The antimicrobial activities of the Bis-Schiff base and its complex were tested in comparison with Ampicillin, Chloramphenicol, Tetracycline, Ofloxacin and Nystatin. Those compounds were found to be active against Gram-positive or Gram-negative bacteria, and had an anti-inflammatory effect comparable to that of Indomethacin.
Keywords:
Bis-Schiff base; Mn(II) complex; anti-inflammatory effect; antimicrobial effect

Issue: 2019, Volume 70, Issue 7
Pages: 2534-2537
Publication date: 2019/8/15
https://doi.org/10.37358/RC.19.7.7375
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Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
TANTARU, G., APOSTU, M., POIATA, A., NICHIFOR, M., BIBIRE, N., PANAINTE, A.D., VIERIU, M., Study of Physico-chemical Characteristics and Pharmacological Effects of 1-Ethyl-Salicyldene-bis-Ethylene-Diamine and Its Complex with Mn(II), Rev. Chim., 70(7), 2019, 2534-2537.

Vancouver
Tantaru G, Apostu M, Poiata A, Nichifor M, Bibire N, Panainte AD, Vieriu M. Study of Physico-chemical Characteristics and Pharmacological Effects of 1-Ethyl-Salicyldene-bis-Ethylene-Diamine and Its Complex with Mn(II). Rev. Chim.[internet]. 2019 Jul;70(7):2534-2537. Available from: https://doi.org/10.37358/RC.19.7.7375


APA 6th edition
Tantaru, G., Apostu, M., Poiata, A., Nichifor, M., Bibire, N., Panainte, A.D. & Vieriu, M. (2019). Study of Physico-chemical Characteristics and Pharmacological Effects of 1-Ethyl-Salicyldene-bis-Ethylene-Diamine and Its Complex with Mn(II). Revista de Chimie, 70(7), 2534-2537. https://doi.org/10.37358/RC.19.7.7375


Harvard
Tantaru, G., Apostu, M., Poiata, A., Nichifor, M., Bibire, N., Panainte, A.D., Vieriu, M. (2019). 'Study of Physico-chemical Characteristics and Pharmacological Effects of 1-Ethyl-Salicyldene-bis-Ethylene-Diamine and Its Complex with Mn(II)', Revista de Chimie, 70(7), pp. 2534-2537. https://doi.org/10.37358/RC.19.7.7375


IEEE
G. Tantaru, M. Apostu, A. Poiata, M. Nichifor, N. Bibire, A.D. Panainte, M. Vieriu, "Study of Physico-chemical Characteristics and Pharmacological Effects of 1-Ethyl-Salicyldene-bis-Ethylene-Diamine and Its Complex with Mn(II)". Revista de Chimie, vol. 70, no. 7, pp. 2534-2537, 2019. [online]. https://doi.org/10.37358/RC.19.7.7375


Text
Gladiola Tantaru, Mihai Apostu, Antonia Poiata, Mihai Nichifor, Nela Bibire, Alina Diana Panainte, Madalina Vieriu,
Study of Physico-chemical Characteristics and Pharmacological Effects of 1-Ethyl-Salicyldene-bis-Ethylene-Diamine and Its Complex with Mn(II),
Revista de Chimie,
Volume 70, Issue 7,
2019,
Pages 2534-2537,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.7.7375.
(https://revistadechimie.ro/Articles.asp?ID=7375)
Keywords: Bis-Schiff base; Mn(II) complex; anti-inflammatory effect; antimicrobial effect


RIS
TY - JOUR
T1 - Study of Physico-chemical Characteristics and Pharmacological Effects of 1-Ethyl-Salicyldene-bis-Ethylene-Diamine and Its Complex with Mn(II)
A1 - Tantaru, Gladiola
A2 - Apostu, Mihai
A3 - Poiata, Antonia
A4 - Nichifor, Mihai
A5 - Bibire, Nela
A6 - Panainte, Alina Diana
A7 - Vieriu, Madalina
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 7
SP - 2534
EP - 2537
UR - https://doi.org/10.37358/RC.19.7.7375
KW - Bis-Schiff base
KW - Mn(II) complex
KW - anti-inflammatory effect
KW - antimicrobial effect
ER -


BibTex
@article{RevCh2019P2534,
author = {Tantaru Gladiola and Apostu Mihai and Poiata Antonia and Nichifor Mihai and Bibire Nela and Panainte Alina Diana and Vieriu Madalina},
title = {Study of Physico-chemical Characteristics and Pharmacological Effects of 1-Ethyl-Salicyldene-bis-Ethylene-Diamine and Its Complex with Mn(II)},
journal = {Revista de Chimie},
volume = {70},
number = {7},
pages = {2534-2537},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.7.7375},
url = {https://revistadechimie.ro/Articles.asp?ID=7375}
}
 
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