Endometriosis of the Abdominal Wall - Clinical, Histopathological and Immunohistochemical Aspects

Ofiteru, Anca Maria Istrate; Berceanu, Sabina; Paitici, Stefan; Rosu, Gabriela Camelia; Iovan, Larisa; Voicu, Nicoleta Loredana; Pirici, Daniel; Mogoanta, laurentiu; Vladareanu, Radu; Mehedintu, Claudia; Bratila, Elvira; Bratu, Ovidiu; Berceanu, Costin

Anca Maria Istrate Ofiteru, Sabina Berceanu, Stefan Paitici, Gabriela Camelia Rosu, Larisa Iovan, Nicoleta Loredana Voicu, Daniel Pirici,laurentiu Mogoanta, Radu Vladareanu, Claudia Mehedintu, Elvira Bratila, Ovidiu Bratu, Costin Berceanu

Endometriosis of the Abdominal Wall - Clinical, Histopathological and Immunohistochemical Aspects

Abstract:

Endometriosis is a benign gynecological pathology that mostly affects the organs of the pelvis,but also organs located at a distance maybe affected. Tissue immunohistochemically identified as ectopic endometrium may undergo certain structural and functional changes that may lead to preneoplastic alterations (hyperplasia, dysplasia) in normal cellswhich can evolve to neoplasia. Clinical, genetic, metabolic conditions and local factors may influence degenerationof a benign pathology into a malignant pathology. Endometriosis of the abdominal wall is more frequently encountered, as the number of casarean section has increased. Endometriomas surrounding tissue has a direct impact on the structure of the cells that form the mass. By remodeling cellular morphology, corroborated with the hormonal factors action and the inflammatory response ( via lymphocyte cell secretion), the cell cycle is altered and antiapoptotic activity may be promoted. Immune system via lymphocyte cell secretion, the pressure exerted on the tumor area by surrounding tissueswith its size change, conditioned by the fluctuation of hormonal factors, act directly on the cellular structure and can increase anti-apoptotic action and decrease cell cycle regulation. The presence of endometriomas is identified by the positivity of immunohistochemical reactions for estrogen receptors (ER), progesteron receptors (PR), Cytokeratin 7 (CK7) for endometrial tissue. Negative reaction at Cytokeratin 20 (CK20) shows that the studied area is not a metastasis of a digestive tumor. The presence of abundant inflammatory, peritumoral cells markedwith anti-CD68 / Tryptase for macrophages / mast cells demonstrates the involvement of the inflammatory system in the structural and functional modification of endometrial cells.The pronounced cell division was demonstrated by intense reaction with the anti-Ki67 antibody.The signigicant anti-apoptotic action of the endometrial tissue is shown by the positivity of anti-B cell Lymphoma 2 (BCL2) / anti-Phosphatase and tensin homolog (PTEN) / anti-p53 antibodies.

Keywords:
endometriosis; progesterone receptor; estrogen receptor; Bcl-2; PTEN

Issue: 2019, Volume 70, Issue 8

Pages: 2860-2865

Publication date: 2019/9/15

https://doi.org/10.37358/RC.19.8.7444

Download Pdf Article

This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
OFITERU, A.M.I., BERCEANU, S., PAITICI, S., ROSU, G.C., IOVAN, L., VOICU, N.L., PIRICI, D., MOGOANTA, L., VLADAREANU, R., MEHEDINTU, C., BRATILA, E., BRATU, O., BERCEANU, C., Endometriosis of the Abdominal Wall - Clinical, Histopathological and Immunohistochemical Aspects, Rev. Chim., 70(8), 2019, 2860-2865.

Vancouver
Ofiteru AMI, Berceanu S, Paitici S, Rosu GC, Iovan L, Voicu NL, Pirici D, Mogoanta l, Vladareanu R, Mehedintu C, Bratila E, Bratu O, Berceanu C. Endometriosis of the Abdominal Wall - Clinical, Histopathological and Immunohistochemical Aspects. Rev. Chim.[internet]. 2019 Aug;70(8):2860-2865. Available from: https://doi.org/10.37358/RC.19.8.7444

APA 6th edition
Ofiteru, A.M.I., Berceanu, S., Paitici, S., Rosu, G.C., Iovan, L., Voicu, N.L.,... Berceanu, C. (2019). Endometriosis of the Abdominal Wall - Clinical, Histopathological and Immunohistochemical Aspects. Revista de Chimie, 70(8), 2860-2865. https://doi.org/10.37358/RC.19.8.7444

Harvard
Ofiteru, A.M.I., Berceanu, S., Paitici, S., Rosu, G.C., Iovan, L., Voicu, N.L., Pirici, D., Mogoanta, l., Vladareanu, R., Mehedintu, C., Bratila, E., Bratu, O., Berceanu, C. (2019). 'Endometriosis of the Abdominal Wall - Clinical, Histopathological and Immunohistochemical Aspects', Revista de Chimie, 70(8), pp. 2860-2865. https://doi.org/10.37358/RC.19.8.7444

IEEE
A.M.I. Ofiteru, S. Berceanu, S. Paitici, G.C. Rosu, L. Iovan, N.L. Voicu, D. Pirici, l. Mogoanta, R. Vladareanu, C. Mehedintu, E. Bratila, O. Bratu, C. Berceanu, "Endometriosis of the Abdominal Wall - Clinical, Histopathological and Immunohistochemical Aspects". Revista de Chimie, vol. 70, no. 8, pp. 2860-2865, 2019. [online]. https://doi.org/10.37358/RC.19.8.7444

Text
Anca Maria Istrate Ofiteru, Sabina Berceanu, Stefan Paitici, Gabriela Camelia Rosu, Larisa Iovan, Nicoleta Loredana Voicu, Daniel Pirici,laurentiu Mogoanta, Radu Vladareanu, Claudia Mehedintu, Elvira Bratila, Ovidiu Bratu, Costin Berceanu,
Endometriosis of the Abdominal Wall - Clinical, Histopathological and Immunohistochemical Aspects,
Revista de Chimie,
Volume 70, Issue 8,
2019,
Pages 2860-2865,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.8.7444.
(https://revistadechimie.ro/Articles.asp?ID=7444)
Keywords: endometriosis; progesterone receptor; estrogen receptor; Bcl-2; PTEN

RIS
TY - JOUR
T1 - Endometriosis of the Abdominal Wall - Clinical, Histopathological and Immunohistochemical Aspects
A1 - Ofiteru, Anca Maria Istrate
A2 - Berceanu, Sabina
A3 - Paitici, Stefan
A4 - Rosu, Gabriela Camelia
A5 - Iovan, Larisa
A6 - Voicu, Nicoleta Loredana
A7 - Pirici, Daniel
A8 - Mogoanta, laurentiu
A9 - Vladareanu, Radu
A10 - Mehedintu, Claudia
A11 - Bratila, Elvira
A12 - Bratu, Ovidiu
A13 - Berceanu, Costin
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 8
SP - 2860
EP - 2865
UR - https://doi.org/10.37358/RC.19.8.7444
KW - endometriosis
KW - progesterone receptor
KW - estrogen receptor
KW - Bcl-2
KW - PTEN
ER -

BibTex
@article{RevCh2019P2860,
author = {Ofiteru Anca Maria Istrate and Berceanu Sabina and Paitici Stefan and Rosu Gabriela Camelia and Iovan Larisa and Voicu Nicoleta Loredana and Pirici Daniel and Mogoanta laurentiu and Vladareanu Radu and Mehedintu Claudia and Bratila Elvira and Bratu Ovidiu and Berceanu Costin},
title = {Endometriosis of the Abdominal Wall - Clinical, Histopathological and Immunohistochemical Aspects},
journal = {Revista de Chimie},
volume = {70},
number = {8},
pages = {2860-2865},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.8.7444},
url = {https://revistadechimie.ro/Articles.asp?ID=7444}
}

<<<< back

PUBLISHING SECTION

Author Guidelines

* Paper Drafting

* Paper Template

* Ethical Statement

* Paper Submission

Ghidul Autorului (ro)

Open Access & Archiving Policy

Search Authors

LATEST NEWS
	NUMAR OMAGIAL PETRU PONI.. detalii
	Revista de Chimie - 70 de ani de aparitie neintrerupta.. detalii
	English-Romanian Dictionary for Mechanical Engineering (download pdf)

News, Events

Gold Open Access | Source=http://www.plos.org/ | Author=art designer at PLoS

Conferences of Contemporary
Chemistry

Biblioteca Chimiei

Materiale Plastice

REVISTA DE CHIMIE

About

Board

Indexing