Phytochemical Profile and Total Antioxidant Capacity of Sempervivum ruthenicum Koch Hydroethanolic Extract

Mihai, Sebastian; Dumitrescu, Denisa; Raducanu, Madalina Ana; Stoicescu, Iuliana; Badea, Victoria

Sebastian Mihai, Denisa Dumitrescu, Madalina Ana Raducanu, Iuliana Stoicescu, Victoria Badea

Phytochemical Profile and Total Antioxidant Capacity of Sempervivum ruthenicum Koch Hydroethanolic Extract

Abstract:

The scope of this work is a phytochemical analysis and antioxidant activity assay of a Sempervivum ruthenicum Koch hydroethanolic extract. The hydroethanolic extract was prepared from the dried leaves of the plant by maceration in a water and methanol mixture (50:50 v/v). The total phenolic content of the extract was calculated to be 3.0501±0.0272 mg/mL and the total flavonoid content was determined in a concentration of 3.113±0.0394 mg/mL. The HPLC-DAD analysis revealed phenolic acids and flavonoids, which were quantified. The most prevalent phenolic acids in the extracts were gallic and ellagic acids, with concentrations of 1.2443±0.0475 mg/mL, respectively 0.6339±0.0026 mg/mL. The heteroside astragalin was present in high concentration of 1.1934±0.0754 mg/mL. The DPPH free radical scavenging assay revealed the EC50 value of the extract to be 2.5788±0.003 mg/mL. These results suggest a good scavenging ability of the extract, which is due to the abundance of polyphenolic compounds. The antioxidant activity of the extract demonstrates a high scavenging ability at low doses. Sempervivum ruthenicum Koch shows a promising phytochemical profile that suggests it’s use in pathological conditions that involve high oxidative stress.

Keywords:
Sempervivum ruthenicum; HPLC-DAD; polyphenols; DPPH; antioxidant

Issue: 2019, Volume 70, Issue 1

Pages: 23-26

Publication date: 2019/2/15

https://doi.org/10.37358/RC.19.1.6843

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
MIHAI, S., DUMITRESCU, D., RADUCANU, M.A., STOICESCU, I., BADEA, V., Phytochemical Profile and Total Antioxidant Capacity of Sempervivum ruthenicum Koch Hydroethanolic Extract, Rev. Chim., 70(1), 2019, 23-26.

Vancouver
Mihai S, Dumitrescu D, Raducanu MA, Stoicescu I, Badea V. Phytochemical Profile and Total Antioxidant Capacity of Sempervivum ruthenicum Koch Hydroethanolic Extract. Rev. Chim.[internet]. 2019 Jan;70(1):23-26. Available from: https://doi.org/10.37358/RC.19.1.6843

APA 6th edition
Mihai, S., Dumitrescu, D., Raducanu, M.A., Stoicescu, I. & Badea, V. (2019). Phytochemical Profile and Total Antioxidant Capacity of Sempervivum ruthenicum Koch Hydroethanolic Extract. Revista de Chimie, 70(1), 23-26. https://doi.org/10.37358/RC.19.1.6843

Harvard
Mihai, S., Dumitrescu, D., Raducanu, M.A., Stoicescu, I., Badea, V. (2019). 'Phytochemical Profile and Total Antioxidant Capacity of Sempervivum ruthenicum Koch Hydroethanolic Extract', Revista de Chimie, 70(1), pp. 23-26. https://doi.org/10.37358/RC.19.1.6843

IEEE
S. Mihai, D. Dumitrescu, M.A. Raducanu, I. Stoicescu, V. Badea, "Phytochemical Profile and Total Antioxidant Capacity of Sempervivum ruthenicum Koch Hydroethanolic Extract". Revista de Chimie, vol. 70, no. 1, pp. 23-26, 2019. [online]. https://doi.org/10.37358/RC.19.1.6843

Text
Sebastian Mihai, Denisa Dumitrescu, Madalina Ana Raducanu, Iuliana Stoicescu, Victoria Badea,
Phytochemical Profile and Total Antioxidant Capacity of Sempervivum ruthenicum Koch Hydroethanolic Extract,
Revista de Chimie,
Volume 70, Issue 1,
2019,
Pages 23-26,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.1.6843.
(https://revistadechimie.ro/Articles.asp?ID=6843)
Keywords: Sempervivum ruthenicum; HPLC-DAD; polyphenols; DPPH; antioxidant

RIS
TY - JOUR
T1 - Phytochemical Profile and Total Antioxidant Capacity of Sempervivum ruthenicum Koch Hydroethanolic Extract
A1 - Mihai, Sebastian
A2 - Dumitrescu, Denisa
A3 - Raducanu, Madalina Ana
A4 - Stoicescu, Iuliana
A5 - Badea, Victoria
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 1
SP - 23
EP - 26
UR - https://doi.org/10.37358/RC.19.1.6843
KW - Sempervivum ruthenicum
KW - HPLC-DAD
KW - polyphenols
KW - DPPH
KW - antioxidant
ER -

BibTex
@article{RevCh2019P23,
author = {Mihai Sebastian and Dumitrescu Denisa and Raducanu Madalina Ana and Stoicescu Iuliana and Badea Victoria},
title = {Phytochemical Profile and Total Antioxidant Capacity of Sempervivum ruthenicum Koch Hydroethanolic Extract},
journal = {Revista de Chimie},
volume = {70},
number = {1},
pages = {23-26},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.1.6843},
url = {https://revistadechimie.ro/Articles.asp?ID=6843}
}

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