Textile industry generates a large amount of waste. Thus, many researches have been performed in order to eliminate pollution. Biotechnology could be a feasible solution for the textile waste valorization. The paper presents a preliminary study to recover polyethyleneterephtalate (PET) from cotton blends by treatments with two commercial cellulases which destroy the cotton from the mixture. The influence of different factors: the type of enzyme and the textile material (blends or only cotton) on the biodegradation is studied. The obtained results seem promising for finding a new solution for textile waste valorization.