SONIA MIHAI, MADALINA MALAISTEANU SIZE-DEPENDENT ANTIBACTERIAL OF GOLD COLLOIDS
The bacterial action of colloidal-gold particles on Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa , Candida albicans, were examined by the agar-well-diffusion method. The gold nanoparticles were chemically prepared by reaction of the Schiff base with gold and characterized by transmission electron microscope and UV -Vis spectroscopy. Best antibacterial activity was observed on using small gold colloids (2-5nm) with zone of inhibition 20mm against Staphilococcus aureus.
Keywords: antimicrobial activity, gold nanoparticles, pathogens, TEM