IOAN CALINESCU, GABRIEL MUSTATEA, ADINA IONUTA GAVRILA, ALINA DOBRE, CRISTINA POP SILVER NANOPARTICLES: SYNTHESIS, CHARACTERIZATION AND ANTIBACTERIAL ACTIVITY
Silver nanoparticles have attracted attention because of their unique chemical and physical properties and pronounced antibacterial activity, which provide one of the most cost effective alternatives in developing new antibacterial agents. Preparation of silver nanoparticles by reduction of silver nitrate using polyvinyl alcohol and tannic acid as reducing agents is presented. Colloidal silver nanoparticles obtained have been characterized by Dynamic Light Scattering and UV-Vis analysis indicating the formation of nanoparticles. The antibacterial activity of synthesized nanoparticles against etalon strains of gram-negative bacteria (Escherichia coli) has been studied. The silver nanoparticles showed a strong bactericidal effect against E. coli. The minimum inhibitory concentration (MIC) was also determined. The lowest value for MIC parameter was for nanoparticles having radius below 5 nm, for larger nanoparticles the MIC value increases.