MIRCEA TAMPA, ILINCA NICOLAE, CORINA DANIELA ENE, ISABELA SARBU, CLARA MATEI, SIMONA ROXANA GEORGESCU VITAMIN C AND THIOBARBITURIC ACID REACTIVE SUBSTANCES (TBARS) IN PSORIASIS VULGARIS RELATED TO PSORIASIS AREA SEVERITY INDEX (PASI)
Oxidative stress is caused by an imbalance between the production of pro-oxidants and the capacity of a biological system of rapid detoxification of free radicals. In this paper the level of pro-oxidants and antioxidants was quantified in patients with psoriasis vulgaris. The results of this study show that the level of oxygen reactive species dramatically increases and the physiologic antioxidant mechanisms are inefficient in patients with psoriasis vulgaris. These findings re-confirm that oxidative stress has a destructive and pathogenic potential in psoriasis.