ROXANA CLEOPATRA PENCIU, IULIA POSTOLACHE, ANDREI TICA, LILIANA STERIU, SILVIA IZVORANU, DIANA MOCANU, VASILE SARBU, OANA TICA, MARIANA DEACU5, GABRIELA BALTATESCU, LUCIAN PETCU, IRINA TICA, VLAD IUSTIN TICA GYNECOLOGICAL SYMPTOMS CORRELATED WITH IMMUNOHISTOCHEMICAL ASPECTS OF ENDOMETRIOSIS AND ADENOMYOSIS
Endometriosis is a benign disease characterized by the presence of endometrial tissue outside the uterus. It is more associated to chronic pelvic pain, dysmenorrhea and dyspareunia. Adenomyosis is represented by the presence of endometrial tissue inside the uterine muscle. We studied, in 100 successive patients, immunohistochemical markers CD10, CD34 and KI67 in glandular and in stromal cells, in order to assess the correlation between symptoms and them. We did not find any data reporting these aspects. As CD34 is an angiogenesis marker and Ki67 is an aggressivity marker, pelvic pain could predict a more aggressive disease and with a higher spreading capacity in patients with endometriosis. In the same patients, and dysmenorrhea seems to be related with only with angiogenesis.