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https://doi.org/10.37358/Rev.Chim.1949

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Revista de Chimie (Rev. Chim.), Year 2019, Volume 70, Issue 8, 2879-2882

https://doi.org/10.37358/RC.19.8.7448

Oana Miron, Adina Magdalena Turcanu, Bogdan Mihnea Ciuntu, Vladimir Poroch, Daniel Timofte

The Biochemical Effect of Smoking on the Response to Chemotherapy

Abstract:

Improvements in early detection of cancer have led to an important decrease in mortality rates of cancer. Given the increased incidence rates and decreased mortality rates, the number of patients surviving cancer is rapidly increasing. Although cancer patients face many physical and psychological symptoms, they also continue to engage in poor health behaviors at rates similar to those of the general-healthy population. The prime example of such unhealthy behavior is smoking. The reports show that smoking rates at the time of diagnosis of cancer vary from 10% to 95%. Our study analyzed how the smoking status influenced the outcome of chemotherapy of 249 patients suffering from various forms of cancer. Our statistical analysis showed that patients who smoked had a significant different response to chemotherapy compared to their nonsmoking peers. This meant that in our sample of 149 cancer suffering patients, individuals who did not smoke had a significant better chance of a partial positive response after chemotherapy compared to patients who smoked regularly. Therefore, tobacco smoking is an adverse prognostic factor associated with a resistance to chemotherapy. These results are important given the fact that cancer patients already face a combination of unpleasant symptoms related to their disease but also from the side effects of their treatment. Uncovering the exact mechanisms through which smoking is affecting the outcome of chemotherapy may help in increasing the quality of life, the symptom burden or the final outcome of chemotherapy.
Keywords:
cancer; chemotherapy; tobacco; smoking; side effects; biochemical mechanisms; cancer treatment

Issue: 2019, Volume 70, Issue 8
Pages: 2879-2882
Publication date: 2019/9/15
https://doi.org/10.37358/RC.19.8.7448
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Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
MIRON, O., TURCANU, A.M., CIUNTU, B.M., POROCH, V., TIMOFTE, D., The Biochemical Effect of Smoking on the Response to Chemotherapy, Rev. Chim., 70(8), 2019, 2879-2882.

Vancouver
Miron O, Turcanu AM, Ciuntu BM, Poroch V, Timofte D. The Biochemical Effect of Smoking on the Response to Chemotherapy. Rev. Chim.[internet]. 2019 Aug;70(8):2879-2882. Available from: https://doi.org/10.37358/RC.19.8.7448


APA 6th edition
Miron, O., Turcanu, A.M., Ciuntu, B.M., Poroch, V. & Timofte, D. (2019). The Biochemical Effect of Smoking on the Response to Chemotherapy. Revista de Chimie, 70(8), 2879-2882. https://doi.org/10.37358/RC.19.8.7448


Harvard
Miron, O., Turcanu, A.M., Ciuntu, B.M., Poroch, V., Timofte, D. (2019). 'The Biochemical Effect of Smoking on the Response to Chemotherapy', Revista de Chimie, 70(8), pp. 2879-2882. https://doi.org/10.37358/RC.19.8.7448


IEEE
O. Miron, A.M. Turcanu, B.M. Ciuntu, V. Poroch, D. Timofte, "The Biochemical Effect of Smoking on the Response to Chemotherapy". Revista de Chimie, vol. 70, no. 8, pp. 2879-2882, 2019. [online]. https://doi.org/10.37358/RC.19.8.7448


Text
Oana Miron, Adina Magdalena Turcanu, Bogdan Mihnea Ciuntu, Vladimir Poroch, Daniel Timofte,
The Biochemical Effect of Smoking on the Response to Chemotherapy,
Revista de Chimie,
Volume 70, Issue 8,
2019,
Pages 2879-2882,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.8.7448.
(https://revistadechimie.ro/Articles.asp?ID=7448)
Keywords: cancer; chemotherapy; tobacco; smoking; side effects; biochemical mechanisms; cancer treatment


RIS
TY - JOUR
T1 - The Biochemical Effect of Smoking on the Response to Chemotherapy
A1 - Miron, Oana
A2 - Turcanu, Adina Magdalena
A3 - Ciuntu, Bogdan Mihnea
A4 - Poroch, Vladimir
A5 - Timofte, Daniel
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 8
SP - 2879
EP - 2882
UR - https://doi.org/10.37358/RC.19.8.7448
KW - cancer
KW - chemotherapy
KW - tobacco
KW - smoking
KW - side effects
KW - biochemical mechanisms
KW - cancer treatment
ER -


BibTex
@article{RevCh2019P2879,
author = {Miron Oana and Turcanu Adina Magdalena and Ciuntu Bogdan Mihnea and Poroch Vladimir and Timofte Daniel},
title = {The Biochemical Effect of Smoking on the Response to Chemotherapy},
journal = {Revista de Chimie},
volume = {70},
number = {8},
pages = {2879-2882},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.8.7448},
url = {https://revistadechimie.ro/Articles.asp?ID=7448}
}
 
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