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https://doi.org/10.37358/Rev.Chim.1949

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Revista de Chimie (Rev. Chim.), Year 2008, Volume 59, Issue 11,

https://doi.org/10.37358/RC.08.11.2008

Maria Tomoaia-Cotisel, Aurora Mocanu

Phase Transitions in Phospholipid Monolayers Studied by Atomic Force Microscopy and Langmuir-Blodgett Technique

Abstract:

The phase behaviour and surface structure of dipalmitoyl phosphatidyl choline (DPPC) monolayers at the air/water interface, in the absence and the presence of procaine, have been investigated by Langmuir-Blodgett (LB) technique and atomic force microscopy. The LB films were transferred on mica, at a controlled surface pressure, characteristic for the expanded liquid to condensed liquid phase transition of pure DPPC monolayers. The results indicate that procaine penetrates into and specifically interacts with phospholipid monolayers stabilizing the lipid membrane interface.

Keywords:
DPPC; procaine; LB monolayers; AFM

Issue: 2008, Volume 59, Issue 11
Pages:
Publication date: 2008/10/9
https://doi.org/10.37358/RC.08.11.2008
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