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Revista de Chimie (Rev. Chim.), Year 2009, Volume 60, Issue 11,





Cristiana Radulescu, Claudia Stihi
Biological Activity of New Heterocyclic Systems Containing
Thiazolic Ring

Abstract:

In this study several tests were performed to determine the toxicity and biological activity of some new compact condensed systems with thiazolic ring, obtained by original syntheses which are published in many articles. The presence of N-C-S linkage in the heterocyclic systems, as thiazolic ring, has been determined antimicrobial and antifungal activity. So, these new heterocyclic systems, obtained for the first time by authors, have been screened in vitro for antimicrobial activity determination against various strains of bacteria and fungi. Most of the compounds have shown significant antifungal activity while few have shown excellent antimicrobial activity. An attempt is made to study the compounds and biological activity relationship. Keywords: compact condensed system, thiazolic ring, acute toxicity, antimicrobial activity, antifungal activity


Issue: 2009, Volume 60, Issue 11
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