Bogdan Tita, Geza Bandur, Dumitru Tita<br>Novel Cu(II) Complex with Non-steroidal Anti-inflammatory Drugs<br>Synthesis, characterization and thermal investigation <br>of the complex with ibuprofen

Bogdan Tita, Geza Bandur, Dumitru Tita
Novel Cu(II) Complex with Non-steroidal Anti-inflammatory Drugs
Synthesis, characterization and thermal investigation
of the complex with ibuprofen

Abstract:

Copper (II) complex with the non-steroidal anti-inflammatory drug (NSAID) ibuprofen has been synthesised and characterized. The complex was characterized by elemental analysis, FT-IR spectroscopy, X-ray powder diffraction and thermal analysis. By the mentioned methods, but especially elemental and thermal analysis was determined the following empirical formula: [Cu(IB)2]2. The FT-IR spectroscopy and X-ray powder diffraction show that the crystal structure of [Cu(IB)2]2 consist of a binuclear quadruply-bridged neutral molecule. The four carboxylate groups from four ligands are in the familiar bidentate bridging mode. The thermal investigation was performed by simultaneous TG/DTG/DTA methods, under non-isothermal conditions and in a dynamic air atmosphere. According to the thermal curves, especially TG curves, the complex is not containing water of co-ordination or crystallization. The process of thermal decomposition is a complex one and the final product, formed at 1034 C, was metallic copper. Keywords: anti-inflammatory drug, ibuprofen, elemental analysis, FT-IR spectroscopy, X-ray analysis, thermal analysis

Issue: 2013, Volume 64, Issue 6

Pages:

Download Pdf Article

This article is published under the Creative Commons Attribution 4.0 International License

<<<< back

PUBLISHING SECTION

Author Guidelines

* Paper Drafting

* Paper Template

* Ethical Statement

* Paper Submission

Ghidul Autorului (ro)

Open Access & Archiving Policy

Search Authors

LATEST NEWS
	NUMAR OMAGIAL PETRU PONI.. detalii
	Revista de Chimie - 70 de ani de aparitie neintrerupta.. detalii
	English-Romanian Dictionary for Mechanical Engineering (download pdf)