Viorel Ordeanu,  Diana M. Popescu, Gabriela V. Dumitrescu, Simona N. Bicheru, Emilia BArbulescu, Marius NecSulescu, Lucia E. Ionescu<br>Synthesis and Testing of New Decontaminant “bio-chem” <br>Based on Quaternary Ammonium Compounds

Viorel Ordeanu, Diana M. Popescu, Gabriela V. Dumitrescu, Simona N. Bicheru, Emilia BArbulescu, Marius NecSulescu, Lucia E. Ionescu
Synthesis and Testing of New Decontaminant “bio-chem”
Based on Quaternary Ammonium Compounds

Abstract:

Decontamination after biological attacks and / or chemical terrorist attacks or industrial accidents with “bio-chem” agents must be fast and efficient in order to reduce the number of victims and to erase the traces of the event. The decontamination of living or non-living biological agents and toxic chemicals can be achieved by hydrolysis in the different experimental conditions, in particular in an alkaline medium, reaction with amines or ammonia, alcohols and phenols, etc.. and transformation into less toxic degradation products. Intentional or unintentional “bio-chem” contamination, is a real risk, to which must have effective management to prevent and combat. Decontamination is an essential measure to protect the personnel and the environment. The synthesis and testing of new “bio-chem” decontaminant agents, based on quaternary ammonium salts, completes the arsenal of protection from chemical and biological agents. The synthesized substances that were tested by us for “bio-chem” decontamination are effective due to their specific action, less toxicity, easy to prepare and use and low costs. The most efficient substances that were selected can be produced and used for decontamination, in accordance with the law. Keywords: “bio-chem” contamination, decontamination, disinfectants, quaternary ammonium salts, synthetic chemical, microbiological testing

Issue: 2015, Volume 66, Issue 4

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