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Cite as: Rev. Chim.
https://doi.org/10.37358/Rev.Chim.1949

OSIM Nr. R102355
ISSN Online 2668-8212
ISSN Print: 1582-9049
ISSN-L: 1582-9049

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Revista de Chimie (Rev. Chim.), Year 2015, Volume 66, Issue 7,





CORINA DANCIU, MARIUS BIRIS, BOGLÁRKA BALÁZS, ERZSÉBET CSÁNYI,IOANA ZINUCA PAVEL, GEORGETA POP, CODRUTA SOICA, LAVINIA CEUTA, LUCIAN NITA,CLAUDIU MORGOVAN, DANA STOIAN
Pro-apoptotic Effect of Soy Total Extract Incorporated
in Lyotropic Liquid Crystals Formulation

Abstract:

The paper aims to test the pro apoptotic capacity of soy total extract on the B164A5 mouse melanoma cells alone and after incorporation in the modern formulation lyotropic liquid crystals. DAPI dye and Annexin-FITC-7AAD double staining show that soy extract present both early and late apoptotic properties against B164A5 murine melanoma cell line. Furthermore , incorporation of soy extract in the modern formulation does not affect in a negative manner this property. As explained in the paper the benefits of such an approach, this preliminary study represent an obvious proof that incorporation of soy extract in this new formulation is a good option for furtherer in vivo studies on animal model of melanoma. Keywords: soy extract, lyotropic liquid crystals, murine melanoma, apoptosis


Issue: 2015, Volume 66, Issue 7
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