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REVISTA DE CHIMIE
Cite as: Rev. Chim.
https://doi.org/10.37358/Rev.Chim.1949

OSIM Nr. R102355
ISSN Online 2668-8212
ISSN Print: 1582-9049
ISSN-L: 1582-9049

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Revista de Chimie (Rev. Chim.), Year 2015, Volume 66, Issue 9,





IULIANA ISVORANU, ILEANA PERIDE, DANIELA RADULESCU, ANDREI NICULAE, RUXANDRA DIANA SINESCU, IONEL ALEXANDRU CHECHERITA
Inflammatory Effects of Dialysis Solutions on Peritoneal
Membrane in Peritoneal Dialysis Patients

Abstract:

In long-term peritoneal dialysis, peritoneal membrane suffers structural and functional changes, being exposed to various proinflammatory insults, which ultimately lead to sclerosis and ultrafiltration failure and require transferring the patients on hemodialysis. Inflammatory status of uremia, recurrent peritonitis episodes, presence of the dialysis catheter and repeatable contact with non-physiological dialysis solutions are all involved in the alterations of peritoneal membrane. This article reviews the harmful effects of the currently used dialysis solutions on the structure and functionality of the peritoneal membrane and presents also the future promises for better alternatives. Keywords: peritoneal dialysis, dialysis solutions, inflammation, membrane failure

Issue: 2015, Volume 66, Issue 9
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