OANA PARTENI, CEZAR-DORU RADU, AUGUSTIN MURESAN, ANDREI VICTOR SANDU, LOTI-CORNELIA OPROIU, LUMINITA CIOBANU, IOAN GABRIEL SANDU<br>Textile Performances of Some Biomaterials with Controlled <br>Release of a Drug for Cutaneous Therapies

OANA PARTENI, CEZAR-DORU RADU, AUGUSTIN MURESAN, ANDREI VICTOR SANDU, LOTI-CORNELIA OPROIU, LUMINITA CIOBANU, IOAN GABRIEL SANDU
Textile Performances of Some Biomaterials with Controlled
Release of a Drug for Cutaneous Therapies

Abstract:

The paper is focused on the aspects of moisture, air, water vapor and heat transfer from human body to the environment, in the case of a textile material (100 % cotton knitting fabric with interlock structure), on which a layer of hydrogel or cyclodextrin derivative (mono chloro tryazinil-b-cyclodextrin) has been deposited, or a multilayer arrangement was executed with chitosan (CS) and sodium alginate (Alg) layers, alternately deposited. On the textile surface, one of the following medicines: hydrocortisone acetate (HCr), tacrolimus (TAC) and honokiol (HNK) has been inserted. The active principles are used in coetaneous therapies. One evaluates the comfort elements concerning textile wearing in assembly garments, whose main role is to release a drug from a textile surface to dermis. Tests have been performed on thickness, thermal conductivity, water adsorption, air and vapor permitivity of a basic textile material after chemical treatments meant to insert the hydrogel and cyclodextrin derivative. One obtained a relationship and a general overview between chemical treatments and the textile answer to comfort requirements of a garment, which is a therapeutic support for coetaneous pathologies. Keywords: comfort, thermal conductivity, air and vapor permitivity

Issue: 2015, Volume 66, Issue 11

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