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https://doi.org/10.37358/Rev.Chim.1949

OSIM Nr. R102355
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Revista de Chimie (Rev. Chim.), Year 2015, Volume 66, Issue 12,





VALERIU ARDELEANU, MICHAELA DOBRE, ELIA MONICA GEORGESCU
Deep Facial Wrinkle Treatment Outcome
After First Injection of Reticulated Hyaluronic Acid

Abstract:

Skin aging is a complex multifactorial biological process that affects different skin components. Even if the skin aging mechanism is not fully elucidated yet, it is shown that with time, the epidermis loses the hyaluronic acid (HA), resulting in decreased skin tonicity and hydration level. HA properties - as glycosaminoglycan, present in all conjunctive and epithelial tissues and as biological skin moisturizer that attracts and retains averagely 70% of its weight in water - lead to its usage as dermocosmetic. When talking about wrinkles incidence, they can appear in all persons, depending on age, genes, environmental and dietary factors, etc. The present study is about the use of reticulated HA of non-animal origin in treating deep wrinkles, assessing its effects in time, as well as the side-effects. The study was conducted in aBeauty Clinique centres in Romania, on 164 subjects. Treatment outcomes were evaluated according to biological factors, habits or lifestyle as risk factors, tolerability, effectiveness, lastingness, adverse reactions and complications, and HA dosage. Keywords: skin, aging, wrinkles, fillers, hyaluronic acid


Issue: 2015, Volume 66, Issue 12
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