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https://doi.org/10.37358/Rev.Chim.1949

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Revista de Chimie (Rev. Chim.), Year 2016, Volume 67, Issue 1,



Cezar-Doru Radu, Oana Parteni, Ioan Gabriel Sandu, Gabriela Lisa, Corneliu Munteanu, Vasile Valeriu Lupu

Specific Characterization of a Multilayer Biomaterial Controlled Release of Tacrolimus

Abstract:

The article presents thermogravimetric (DTG and DSC) and dyeing data (color strength index, K/S and color difference, DE) as well as SEM micropictures of the layers of a biomaterial composed of chitosan (CS) and sodium alginate (Alg) films, alternatively deposited onto a cotton woven fabric. The biomaterial having CS as the last applied layer was dyed with an acid dyestuff, and the one having Alg as the last applied layer was dyed with a basic dyestuff, respectively. Between the last layers of CS and Alg, an amount of tacrolimus (Ta), a drug used for the treatment of psoriasis, was also applied.
Keywords:
multilayer; chitosan; sodium alginate; tacrolimus; thermogravimetric behavior; dyeing tests

Issue: 2016, Volume 67, Issue 1
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