Diagnostic Value of Chemical and Hematological Markers in Children Acute Abdominal Pain

Gurau, Gabriela; Dinu, Ciprian Adrian; Earar, Kamel; Voicu, Dragos Cristian; Botezatu, Dan

Gabriela Gurau, Ciprian Adrian Dinu, Kamel Earar, Dragos Cristian Voicu, Dan Botezatu

Diagnostic Value of Chemical and Hematological Markers in Children Acute Abdominal Pain

Abstract:

Acute appendicitis, acute appendicitis with peritoneal abscess, acute gastroenteritis, lymphadenitis and gastroduodenitis raises serious health problems in children. The purpose of this study consisted in screening of hematological and biochemical markers to establish their significance especially in the case of abdominal diseases with nonspecific or severe symptoms. Data were collected prospectively from 10750 hospitalized children, of which 2538 with abdominal pain, boys 39%, girls 61%, coming from different social backgrounds: 57.8% urban, and 42.2% rural areas. Children with symptoms of acute appendicitis (52.7%) prevailed. Hematological and biochemical parameters of blood were determined by spectrophotometric, potentiometric, immunological and electrical impedance methods. Results. The majority of children with acute abdominal pain investigate (2358) had white blood cells, sedimentation rate of erythrocytes, neutrophils and lymphocytes percentages and C-reactive protein level exceeded the maximum limit of reference. C-reactive protein values were higher in children with clinical suspicion of acute appendicitis and mesenteric lymphadenitis, this marker is the first that react in cases of inflammations and infections. Inflammatory markers analyzed separately taking have no diagnostic value. The levels of white blood cells, sedimentation rate of erythrocytes and C-reactive protein increased together with neutrophil/lymphocyte high ratio, helpful pediatrician to establish an accurate diagnosis in a shorter time for the correct management of acute abdominal diseases.

Keywords:
acute abdominal disease; C-reactive protein; blood cells; natremia; potassemia

Issue: 2016, Volume 67, Issue 3

Pages:

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This article is published under the Creative Commons Attribution 4.0 International License

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